The KO Repository models exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of
order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Models are stored primarily as cryopreserved sperm on a
mixed 129S5 x C57BL/6J-
Tyrc-Brd background. Models are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some models are stored as
cryopreserved embryos and when revitalized will result in a 129S5 x C57BL/6J-
Tyrc-Brd background.
For standard orders clients will receive:
- A minimum of four (4) mutant mice, heterozygous for the selected mutation on a mixed 129S5;B6 background.
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Validated genotyping protocols
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Animal health data
Let Taconic be your source for expertise in generating, breeding, testing, and delivering genetically engineered models.