Taconic Biosciences' Dr. Philip Dubé discusses mouse models used to study immuno-oncology in this video excerpt from the webinar, "Advanced Toolkit For Syngeneic Tumor Modeling in Mice".
There are essentially two types of models used in pre-clinical immuno-oncology research:
- Syngeneic models — a mouse tumor is implanted into a genetically identical and immuno-competent host
- Humanized models — severely immuno-deficient mice are implanted with both a human immune system and a human tumor
For more information on the Taconic Biosciences' models mentioned and their applications see:
Watch the Complete Taconic Biosciences' Webinar: