Taconic Biosciences' Dr. Megan MacBride penned this article for AALAS to discuss how to properly care for humanized mice such as allowing time to acclimate, limit handling, among other suggestions worth heeding:
"When lab mice are received at a research facility, investigators typically are eager to enroll them in a study as soon as possible. That's understandable, given the pressure to speed drug discovery and accelerate time-to-market with new therapies. Yet lab mice need to acclimate to their new environment properly, or they risk being subjected to stresses that can impact their health and welfare as well as the study outcome. This is especially true of humanized mouse models, which need special housing and husbandry."
Read* the complete article at: AALAS.org
"When lab mice are received at a research facility, investigators typically are eager to enroll them in a study as soon as possible. That's understandable, given the pressure to speed drug discovery and accelerate time-to-market with new therapies. Yet lab mice need to acclimate to their new environment properly, or they risk being subjected to stresses that can impact their health and welfare as well as the study outcome. This is especially true of humanized mouse models, which need special housing and husbandry."