hIL-2 NOG Publications

hIL-2 NOG Model Page

Filter publications by application: All Antibody-Dependent-Cellular Cytotoxicity (ADCC) Gene/Cell therapy Humanized Immuno-Oncology Immunology Immunotherapy Leukemia Melanoma NK Oncology T And/Or B Cell Function Transplantation Research And Graft Versus Host Disease (GVHD)
Filter publications by model type: All Humanization Random integration transgene

Author(s)

(Date)

Paper Title

Citation

Model Type

Applications

Full Text

Ny L, et al.
Mouse over for full list
Ny L, Rizzo LY, Belgrano V, Karlsson J, Jespersen H, Carstam L, Bagge RO, Nilsson LM, Nilsson JA
(2020) Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse models. Ann Oncol 31(2):266-273
Helleday T
Mouse over for full list
Helleday T
(2020) Using personalized immune-humanized xenograft mouse models to predict immune checkpoint responses in malignant melanoma: potential and hurdles. Ann. Oncol. 31(2):167-168
Forsberg EM, et al.
Mouse over for full list
Forsberg EM, Lindberg MF, Jespersen H, Alsén S, Olofsson Bagge R, Donia M, Svane IM, Nilsson O, Ny L, Nilsson LM, Nilsson JA
(2019) HER2 CAR-T cells eradicate uveal melanoma and T cell therapy-resistant human melanoma in interleukin-2 (IL-2) transgenic NOD/SCID IL-2 receptor knockout mice. Cancer Res.
Einarsdottir BO, et al.
Mouse over for full list
Einarsdottir BO, Karlsson J, Söderberg EMV, Lindberg MF, Funck-Brentano E, Jespersen H, Brynjolfsson SF, Bagge RO, Carstam L, Scobie M, Koolmeister T, Wallner O, Stierner U, Berglund UW, Ny L, Nilsson LM, Larsson E, Helleday T, Nilsson JA
(2018) A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma. Cell Death Dis 9(8):810
Humanization, Random integration transgene
T And/Or B Cell Function, Oncology, Melanoma, Humanized
Paul Volden, et al.
Mouse over for full list
Paul Volden, Azusa Tanaka, Dimitri Gimnopoulos, Magdalena Paterka, Iduna Fichtner
(2018) Cytokine-transgenic NOG mice engrafted with human peripheral blood cells support natural killer cell expansion   American Association for Cancer Research 2018 Conference
Humanization, Random integration transgene
Immunology, NK, Antibody-Dependent-Cellular Cytotoxicity (ADCC), Transplantation Research And Graft Versus Host Disease (GVHD), Immunotherapy, Immuno-Oncology, Gene/Cell therapy
Jespersen H, et al.
Mouse over for full list
Jespersen H, Lindberg MF, Donia M, Söderberg EMV, Andersen R, Keller U, Ny L, Svane IM, Nilsson LM, Nilsson JA
(2017) Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model. Nat Commun 8(1):707
Humanization
Immunology, Oncology, Humanized
Ito R, et al.
Mouse over for full list
Ito R, Katano I, Kawai K, Yagoto M, Takahashi T, Ka Y, Ogura T, Takahashi R, Ito M
(2016) A novel xenogeneic graft-versus-host disease model for investigating the pathological role of human CD4+ or CD8+ T cells using immunodeficient NOG mice. Am. J. Transplant.
Katano I, et al.
Mouse over for full list
Katano I, Takahashi T, Ito R, Kamisako T, Mizusawa T, Ka Y, Ogura T, Suemizu H, Kawakami Y, Ito M
(2015) Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse. J. Immunol. 194(7):3513-25
Fukuchi Y, et al.
Mouse over for full list
Fukuchi Y, Miyakawa Y, Kobayashi K, Kuramochi T, Shimamura K, Tamaoki N, Nomura T, Ueyama Y, Ito M
(1998) Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice. Leuk. Res. 22(9):837-43
Oncology, Leukemia, Humanized
Mamoru Ito, et al.
Mouse over for full list
Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi, Kazutomo Suzue, Mariko Kawahata, Kyoji Hioki, Yoshito Ueyama, Yoshio Koyanagi, Kazuo Sugamura, Kohichiro Tsuji, Toshio Heike, Tatsutoshi Nakahata
(2002) NOD/SCID/γ nullc mouse: an excellent recipient mouse model for engraftment of human cells Blood 2002 100:3175-3182
Humanized
Close

Welcome! Tell us a little about yourself