Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Schmidt J, et al. Mouse over for full list |
(2023) | Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors. | Nat Commun 14(1):3188 | T And/Or B Cell Function, Oncology, Colon Cancer, Immunotherapy, Lung Cancer, Melanoma, Immuno-Oncology | ||
| Hall MS, et al. Mouse over for full list |
(2022) | Combination Nivolumab, CD137 Agonism, and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma | Clin Cancer Res. 2022 Dec 15;28(24):5317-5329. | T And/Or B Cell Function, Oncology, Immunotherapy, Melanoma, Patient Derived Xenograft (PDX), Immuno-Oncology, Gene/Cell therapy | ||
| Christensen PKF, et al. Mouse over for full list |
(2023) | Sustaining the T-cell activity in xenografted psoriasis skin | PLoS One. 2023 Jan 17;18(1):e0278390. | Autoimmune, T And/Or B Cell Function | ||
| Eliana Ruggiero, et al. Mouse over for full list |
(2021) | NTLA5001, a T Cell Product Candidate with CRISPR-Based Targeted Insertion of a High-Avidity, Natural, WT1-Specific TCR, Shows Efficacy in In Vivo Models of AML and ALL | ASH 2021 presentation | T And/Or B Cell Function, Oncology, Immunotherapy, Leukemia, Immuno-Oncology, Gene/Cell therapy | ||
| Forsberg EMV, et al. Mouse over for full list |
(2023) | Treatment with Anti-HER2 Chimeric Antigen Receptor Tumor-Infiltrating Lymphocytes (CAR-TILs) Is Safe and Associated with Antitumor Efficacy in Mice and Companion Dogs | Cancers 2023, 15(3), 648 | Immunotherapy, Melanoma, Immuno-Oncology, Gene/Cell therapy | ||
| Liang F, et al. Mouse over for full list |
(2022) | A Fraction of CD8+ T Cells from Colorectal Liver Metastases Preferentially Repopulate Autologous Patient-Derived Xenograft Tumors as Tissue-Resident Memory T Cells. | Cancers (Basel) 14(12) | |||
| Hofving T, et al. Mouse over for full list |
(2021) | The Microenvironment of Small Intestinal Neuroendocrine Tumours Contains Lymphocytes Capable of Recognition and Activation after Expansion. | Cancers (Basel) 13(17) | Oncology, Immuno-Oncology | ||
| Tatiana V. Kudling, et al. Mouse over for full list |
(2022) | Local delivery of interleukin 7 with an oncolytic adenovirus activates tumor-infiltrating lymphocytes and causes tumor regression | OncoImmunology, 11:1, DOI: 10.1080/2162402X.2022.2096572 | Oncology, Patient Derived Xenograft (PDX), Immuno-Oncology | ||
| Arnaud M, et al. Mouse over for full list |
(2022) | Sensitive identification of neoantigens and cognate TCRs in human solid tumors. | Nat Biotechnol | |||
| Muralidharan SV, et al. Mouse over for full list |
(2020) | Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells. | Life Sci Alliance 3(8) | |||
| �?nar �, et al. Mouse over for full list |
(2021) | High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies. | J Immunother Cancer 9(7) | |||
| Ny L, et al. Mouse over for full list |
(2020) | Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse models. | Ann Oncol 31(2):266-273 | |||
| Helleday T Mouse over for full list |
(2020) | Using personalized immune-humanized xenograft mouse models to predict immune checkpoint responses in malignant melanoma: potential and hurdles. | Ann. Oncol. 31(2):167-168 | |||
| Forsberg EM, et al. Mouse over for full list |
(2019) | HER2 CAR-T cells eradicate uveal melanoma and T cell therapy-resistant human melanoma in interleukin-2 (IL-2) transgenic NOD/SCID IL-2 receptor knockout mice. | Cancer Res. | |||
| Einarsdottir BO, et al. Mouse over for full list |
(2018) | A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma. | Cell Death Dis 9(8):810 | Humanization, Random integration transgene |
T And/Or B Cell Function, Oncology, Melanoma, Humanized | |
| Paul Volden, et al. Mouse over for full list |
(2018) | Cytokine-transgenic NOG mice engrafted with human peripheral blood cells support natural killer cell expansion � | American Association for Cancer Research 2018 Conference | Humanization, Random integration transgene |
Immunology, NK, Antibody-Dependent-Cellular Cytotoxicity (ADCC), Transplantation Research And Graft Versus Host Disease (GVHD), Immunotherapy, Immuno-Oncology, Gene/Cell therapy | |
| Jespersen H, et al. Mouse over for full list |
(2017) | Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model. | Nat Commun 8(1):707 | Humanization |
Immunology, Oncology, Humanized | |
| Ito R, et al. Mouse over for full list |
(2016) | A novel xenogeneic graft-versus-host disease model for investigating the pathological role of human CD4+ or CD8+ T cells using immunodeficient NOG mice. | Am. J. Transplant. | |||
| Katano I, et al. Mouse over for full list |
(2015) | Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse. | J. Immunol. 194(7):3513-25 |
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