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Tomaszewski MR, et al. Mouse over for full list |
(2023) | Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment. | J Lipid Res 64(8):100408 | Neuroscience, Metabolic Syndrome | ||
Urva S, et al. Mouse over for full list |
(2020) | The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP-1 receptor agonists. | Diabetes Obes Metab 22(10):1886-1891 | |||
Quante M, et al. Mouse over for full list |
(2021) | Restored TDCA and valine levels imitate the effects of bariatric surgery. | Elife 10 | |||
Bartesaghi S, et al. Mouse over for full list |
(2022) | Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice. | Mol Ther Nucleic Acids 28:500-513 | Therapeutic Efficacy Evaluation, Metabolic Syndrome, NAFLD/NASH | ||
Schwartzkopf CD, et al. Mouse over for full list |
(2022) | Beneficial Metabolic Effects of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in a Mouse Diet-Induced Obesity Model. | Front Pharmacol 13:852080 | |||
Madhavan A, et al. Mouse over for full list |
(2022) | Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity. | Nat Commun 13(1):608 | Metabolism, Diabetes (Type 2), Metabolic Syndrome, NAFLD/NASH | ||
Fergusson G, et al. Mouse over for full list |
(2014) | Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice. | Mol Metab 3(9):848-54 | Metabolic Syndrome | ||
Fisher-Wellman KH, et al. Mouse over for full list |
(2016) | A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice. | Diabetes 65(11):3249-3261 | |||
Blumenfeld NR, et al. Mouse over for full list |
(2018) | A direct tissue-grafting approach to increasing endogenous brown fat. | Sci Rep 8(1):7957 | Stem Cells/Regenerative Medicine/Tissue Engineering, Metabolic Syndrome | ||
Wang Z, et al. Mouse over for full list |
(2019) | Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade. | Nat. Med. 25(1):141-151 | Oncology | ||
Mullican SE, et al. Mouse over for full list |
(2017) | GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. | Nat. Med. | Metabolism | ||
Holst B, et al. Mouse over for full list |
(2013) | PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance. | PLoS Biol. 11(4):e1001542 | |||
Camacho S, et al. Mouse over for full list |
(2015) | Anti-obesity and anti-hyperglycemic effects of cinnamaldehyde via altered ghrelin secretion and functional impact on food intake and gastric emptying. | Sci Rep 5:7919 | |||
Penke M, et al. Mouse over for full list |
(2015) | Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet. | Mol. Cell. Endocrinol. 412:65-72 | |||
Chen Y, et al. Mouse over for full list |
(2016) | A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes. | Pharmacol Res Perspect 4(6):e00278 | Diabetes (Type 2) | ||
Shin Wen, et al. Mouse over for full list |
(2013) | Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice | Journal of lipids | |||
L.M. Vaanholt, et al. Mouse over for full list |
(2015) | Factors influencing individual variability in high fat diet-induced weight gain in out-bred MF1 mice | Physiology & Behavior Volume 144, 15 May 2015, Pages 146�155 | |||
Fontaine DA, et al. Mouse over for full list |
(2016) | Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse Consortium. | Diabetes 65(1):25-33 | |||
Montgomery MK, et al. Mouse over for full list |
(2013) | Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding. | Diabetologia 56(5):1129-39 | |||
Pettersson US, et al. Mouse over for full list |
(2012) | Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue. | PLoS ONE 7(9):e46057 | |||
Vickers SP, et al. Mouse over for full list |
(2011) | The utility of animal models to evaluate novel anti-obesity agents. | Br. J. Pharmacol. 164(4):1248-62 | |||
Hariri N, et al. Mouse over for full list |
(2010) | High-fat diet-induced obesity in animal models. | Nutr Res Rev 23(2):270-99 | |||
Bradley RL, et al. Mouse over for full list |
(2008) | Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice. | Am. J. Physiol. Endocrinol. Metab. 295(3):E586-94 | |||
Anderson SR, et al. Mouse over for full list |
(2008) | Diet-induced obesity alters protein synthesis: tissue-specific effects in fasted versus fed mice. | Metab. Clin. Exp. 57(3):347-54 | |||
Buettner R, et al. Mouse over for full list |
(2007) | High-fat diets: modeling the metabolic disorders of human obesity in rodents. | Obesity (Silver Spring) 15(4):798-808 | |||
Sumiyoshi M, et al. Mouse over for full list |
(2006) | Chronic intake of high-fat and high-sucrose diets differentially affects glucose intolerance in mice. | J. Nutr. 136(3):582-7 | |||
Hambly C, et al. Mouse over for full list |
(2005) | Mice with low metabolic rates are not susceptible to weight gain when fed a high-fat diet. | Obes. Res. 13(3):556-66 | Metabolic Syndrome | ||
Hu CC, et al. Mouse over for full list |
(2004) | Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice. | Obes. Res. 12(8):1264-70 | |||
Wei P, et al. Mouse over for full list |
(2004) | Glomerular structural and functional changes in a high-fat diet mouse model of early-stage Type 2 diabetes. | Diabetologia 47(9):1541-9 | Diabetes (Type 2) | ||
Xu H, et al. Mouse over for full list |
(2003) | Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. | J. Clin. Invest. 112(12):1821-30 | Inflammation | ||
Harris RB, et al. Mouse over for full list |
(2003) | Leptin resistance in mice is determined by gender and duration of exposure to high-fat diet. | Physiol. Behav. 78(4-5):543-55 | |||
Steppan CM, et al. Mouse over for full list |
(2001) | The hormone resistin links obesity to diabetes. | Nature 409(6818):307-12 | |||
M Van Heek, et al. Mouse over for full list |
(1997) | Diet-induced obese mice develop peripheral, but not central, resistance to leptin. | J Clin Invest. 1997 Feb 1; 99(3): 385�390 | |||
Steven P Vickers, et al. Mouse over for full list |
(2011) | The utility of animal models to evaluate novel anti-obesity agents | Br J Pharmacol. 2011 Oct; 164(4): 1248�1262 | |||
Jina Hong, et al. Mouse over for full list |
(2009) | Differential susceptibility to obesity between male, female and ovariectomized female mice | Nutr J. 2009; 8: 11 | |||
Alesia Walker, et al. Mouse over for full list |
(2014) | Distinct signatures of host�microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet | The ISME Journal (2014) 8, 2380�2396 | |||
Angela M. Gajda, et al. Mouse over for full list |
(2007) | Diet-Induced Metabolic Syndrome in Rodent Models | Animal Lab News | |||
Walker A, et al. Mouse over for full list |
(2014) | Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet. | ISME J 8(12):2380-96 | Infectious Disease, Microbiome | ||
Rajpal DK, et al. Mouse over for full list |
(2015) | Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models. | PLoS ONE 10(12):e0145499 | Diabetes (Type 1), Infectious Disease, Microbiome, Diabetes (Type 2) | ||
Heiker JT, et al. Mouse over for full list |
(2014) | Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains. | Physiol. Genomics 46(11):377-84 | |||
Campbell SC, et al. Mouse over for full list |
(2016) | The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice. | PLoS ONE 11(3):e0150502 | Infectious Disease, Microbiome | ||
Almind K, et al. Mouse over for full list |
(2004) | Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. | Diabetes 53(12):3274-85 | Cardiovascular, Metabolism |
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