Dr. Kenneth Albrecht penned this article in Genetic Engineering & Biotechnology News, specifically about expediting the creation of mouse models:
"Pressure to accelerate drug discovery is high, and can be impacted by how mouse models are generated and bred. This tutorial reviews the use of two techniques that, when combined, reduce the time needed to reach the experimental cohort stage when CRISPR/Cas9-mediated gene editing in embryos is not the best option.
Mouse models are often customized to suit study objectives and improve translatability of results." Read the complete article at: Genengnews.com
"Pressure to accelerate drug discovery is high, and can be impacted by how mouse models are generated and bred. This tutorial reviews the use of two techniques that, when combined, reduce the time needed to reach the experimental cohort stage when CRISPR/Cas9-mediated gene editing in embryos is not the best option. Mouse models are often customized to suit study objectives and improve translatability of results."