Positive results in preclinical research don't always equate to success in the clinic. To bridge the translation gap, animal model providers are continually enhancing and evolving their model portfolios. In an interview with Genetic Engineering & Biotechnology News, Taconic Biosciences' Dr. Terina Martinez discusses one of the company's newest offerings: a humanized immune system model that alleviates graft vs host disease and possesses mutations that make it a good receptor for human immune system engraftment. She also shares other Taconic developments that are helping investigators advance their research:
“For applications that require models that have components of the human immune system, Taconic expanded its existing humanized immune system model portfolio with the introduction of the B2m-NOG mouse. The model is based on the super-immunocompromised NOG model originally developed by the Central Institute for Experimental Animals in Japan.”
Read more at: genengnews.com