Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Hassani-Nezhad-Gashti F, et al. Mouse over for full list Hassani-Nezhad-Gashti F, Rysä J, Kummu O, Näpänkangas J, Buler M, Karpale M, Hukkanen J, Hakkola J |
(2018) | Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver. | Biochem Pharmacol 148:253-264 | |||
| Caparrós-Martín JA, et al. Mouse over for full list Caparrós-Martín JA, Lareu RR, Ramsay JP, Peplies J, Reen FJ, Headlam HA, Ward NC, Croft KD, Newsholme P, Hughes JD, O'Gara F |
(2017) | Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism. | Microbiome 5(1):95 | |||
| Wahlang B, et al. Mouse over for full list Wahlang B, Alexander NC, Li X, Rouchka EC, Kirpich IA, Cave MC |
(2021) | Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis. | Toxicol Rep 8:536-547 | |||
| Wang Z, et al. Mouse over for full list Wang Z, Wu Q, Li X, Klaunig JE |
(2020) | Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse. | Arch Toxicol 94(8):2873-2884 | |||
| Wang Z, et al. Mouse over for full list Wang Z, Li X, Wu Q, Lamb JC, Klaunig JE |
(2017) | Toxaphene-induced mouse liver tumorigenesis is mediated by the constitutive androstane receptor. | J Appl Toxicol 37(8):967-975 | |||
| Scheer N, et al. Mouse over for full list Scheer N, Ross J, Rode A, Zevnik B, Niehaves S, Faust N, Wolf CR |
(2008) | A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. | J. Clin. Invest. 118(9):3228-39 |
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