NOG-EXL (hGM-CSF/hIL-3 NOG) Publications

NOG-EXL (hGM-CSF/hIL-3 NOG) Model Page

Filter publications by application: All Hematopoietic Stem Cell Engraftment Humanized Hypersensitivities Immuno-Oncology Immunology Infectious Disease Inflammation Leukemia Melanoma Oncology Patient Derived Xenograft (PDX) T And/Or B Cell Function Therapeutic Efficacy Evaluation
Filter publications by model type: All

Author(s)

(Date)

Paper Title

Citation

Model Type

Applications

Full Text
Ghoneim MA, et al.
Mouse over for full list
Ghoneim MA, Gabr MM, Refaie AF, El-Halawani SM, Al-Issawi MM, Elbassiouny BL, Kader MAAE, Ismail AM, Zidan MF, Karras MS, Magar RW, Khater SM, Ashamallah SA, Zakaria MM, Kloc M		 (2022) Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice. Stem Cell Res Ther 13(1):350
Dal Bello R, et al.
Mouse over for full list
Dal Bello R, Pasanisi J, Joudinaud R, Duchmann M, Pardieu B, Ayaka P, Di Feo G, Sodaro G, Chauvel C, Kim R, Vasseur L, Chat L, Ling F, Pacchiardi K, Vaganay C, Berrou J, Benaksas C, Boissel N, Braun T, Preudhomme C, Dombret H, Raffoux E, Fenouille N, Clappier E, Adès L, Puissant A, Itzykson R		 (2022) A multiparametric niche-like drug screening platform in acute myeloid leukemia. Blood Cancer J 12(6):95
Oncology, Leukemia, Patient Derived Xenograft (PDX)
Albert DH, et al.
Mouse over for full list
Albert DH, Goodwin NC, Davies AM, Rowe J, Feuer G, Boyiadzis M, Dorritie KA, Mancini M, Gandour-Edwards R, Jonas BA, Borthakur G, Aldoss I, Rizzieri DA, Odenike O, Prebet T, Singh S, Popovic R, Shen YU, McDaniel KF, Kati WM, Modi DA, Motwani M, Wolff JE, Frost DJ		 (2022) Co-clinical Modeling of the Activity of the BET Inhibitor Mivebresib (ABBV-075) in AML. In Vivo 36(4):1615-1627
Oncology, Leukemia, Patient Derived Xenograft (PDX)
Bartels L, et al.
Mouse over for full list
Bartels L, de Jong G, Gillissen MA, Yasuda E, Kattler V, Bru C, Fatmawati C, van Hal-van Veen SE, Cercel MG, Moiset G, Bakker AQ, van Helden PM, Villaudy J, Hazenberg MD, Spits H, Wagner K		 (2019) A Chemo-enzymatically Linked Bispecific Antibody Retargets T Cells to a Sialylated Epitope on CD43 in Acute Myeloid Leukemia. Cancer Res 79(13):3372-3382
Oncology, Leukemia, Therapeutic Efficacy Evaluation, Immuno-Oncology
Roux B, et al.
Mouse over for full list
Roux B, Vaganay C, Vargas JD, Alexe G, Benaksas C, Pardieu B, Fenouille N, Ellegast JM, Malolepsza E, Ling F, Sodaro G, Ross L, Pikman Y, Conway AS, Tang Y, Wu T, Anderson DJ, Le Moigne R, Zhou HJ, Luciano F, Hartigan CR, Galinsky I, DeAngelo DJ, Stone RM, Auberger P, Schenone M, Carr SA, Guirouilh-Barbat J, Lopez B, Khaled M, Lage K, Hermine O, Hemann MT, Puissant A, Stegmaier K, Benajiba L		 (2021) Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Sci Transl Med 13(587)
Pardieu B, et al.
Mouse over for full list
Pardieu B, Pasanisi J, Ling F, Dal Bello R, Penneroux J, Su A, Joudinaud R, Chat L, Wu HC, Duchmann M, Sodaro G, Chauvel C, Castelli FA, Vasseur L, Pacchiardi K, Belloucif Y, Laiguillon MC, Meduri E, Vaganay C, Alexe G, Berrou J, Benaksas C, Forget A, Braun T, Gardin C, Raffoux E, Clappier E, Adès L, de Thé H, Fenaille F, Huntly BJ, Stegmaier K, Dombret H, Fenouille N, Lobry C, Puissant A, Itzykson R		 (2022) Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia. Leukemia 36(6):1585-1595
Lin KH, et al.
Mouse over for full list
Lin KH, Rutter JC, Xie A, Pardieu B, Winn ET, Bello RD, Forget A, Itzykson R, Ahn YR, Dai Z, Sobhan RT, Anderson GR, Singleton KR, Decker AE, Winter PS, Locasale JW, Crawford L, Puissant A, Wood KC		 (2020) Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. Nat Genet 52(4):408-417
Lin KH, et al.
Mouse over for full list
Lin KH, Rutter JC, Xie A, Killarney ST, Vaganay C, Benaksas C, Ling F, Sodaro G, Meslin PA, Bassil CF, Fenouille N, Hoj J, Washart R, Ang HX, Cerda-Smith C, Chaintreuil P, Jacquel A, Auberger P, Forget A, Itzykson R, Lu M, Lin J, Pierobon M, Sheng Z, Li X, Chilkoti A, Owzar K, Rizzieri DA, Pardee TS, Benajiba L, Petricoin E, Puissant A, Wood KC		 (2022) P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia. Nat Cancer
Little CJ, et al.
Mouse over for full list
Little CJ, Haynes WJ, Huang L, Daffada CM, Wolfe KB, Perrin E, Simpson JA, Kropp Schmidt JA, Hinkle HM, Keding LT, Behrens RT, Evans DT, Kaufman DB, Thomson JA, Golos TG, Brown ME		 (2022) Robust engraftment of fetal nonhuman primate CD34-positive cells in immune-deficient mice. J Leukoc Biol
Immunology, Hematopoietic Stem Cell Engraftment, Infectious Disease
Kumar S, et al.
Mouse over for full list
Kumar S, Ghosh S, Sharma G, Wang Z, Kehry MR, Marino MH, Neben TY, Lu S, Luo S, Roberts S, Ramaswamy S, Danaee H, Jenkins D		 (2021) Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models. MAbs 13(1):1954136
Vendramin R, et al.
Mouse over for full list
Vendramin R, Katopodi V, Cinque S, Konnova A, Knezevic Z, Adnane S, Verheyden Y, Karras P, Demesmaeker E, Bosisio FM, Kucera L, Rozman J, Gladwyn-Ng I, Rizzotto L, Dassi E, Millevoi S, Bechter O, Marine JC, Leucci E		 (2021) Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma. J Exp Med 218(9)
Oncology, Melanoma, Patient Derived Xenograft (PDX), Therapeutic Efficacy Evaluation
Tran NT, et al.
Mouse over for full list
Tran NT, Graf R, Wulf-Goldenberg A, Stecklum M, Strauß G, Kühn R, Kocks C, Rajewsky K, Chu VT		 (2020) CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia. Mol Ther 28(12):2621-2634
Dai G, et al.
Mouse over for full list
Dai G, Wanek A, Eddens T, Volden P, Kolls JK		 (2021) Toward a humanized mouse model of Pneumocystis pneumonia. JCI Insight 6(2)
Infectious Disease
Ito R, et al.
Mouse over for full list
Ito R, Katano I, Otsuka I, Takahashi T, Suemizu H, Ito M, Simons PJ		 (2020) Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. Int Immunol
Immunology
Maser IP, et al.
Mouse over for full list
Maser IP, Hoves S, Bayer C, Heidkamp G, Nimmerjahn F, Eckmann J, Ries CH		 (2020) The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models. Front Immunol 11:2082
Verma B, et al.
Mouse over for full list
Verma B, Wesa A		 (2020) Establishment of Humanized Mice from Peripheral Blood Mononuclear Cells or Cord Blood CD34+ Hematopoietic Stem Cells for Immune-Oncology Studies Evaluating New Therapeutic Agents. Curr Protoc Pharmacol 89(1):e77
T And/Or B Cell Function, Humanized
Cidado J, et al.
Mouse over for full list
Cidado J, Boiko S, Proia T, Ferguson D, Criscione SW, San Martin M, Pop-Damkov P, Su N, Roamio Franklin VN, Sekhar Reddy Chilamakuri C, D'Santos CS, Shao W, Saeh JC, Koch R, Weinstock DM, Zinda M, Fawell SE, Drew L		 (2019) AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells. Clin. Cancer Res.
Ghosh S, et al.
Mouse over for full list
Ghosh S, Sharma G, Travers J, Kumar S, Choi J, Jun HT, Kehry M, Ramaswamy S, Jenkins D		 (2019) TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade and . Mol. Cancer Ther. 18(3):632-641
Wang Z, et al.
Mouse over for full list
Wang Z, Sun K, Xiao Y, Feng B, Mikule K, Ma X, Feng N, Vellano CP, Federico L, Marszalek JR, Mills GB, Hanke J, Ramaswamy S, Wang J		 (2019) Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. Sci Rep 9(1):1853
Weaver JL, et al.
Mouse over for full list
Weaver JL, Zadrozny LM, Gabrielson K, Semple KM, Shea KI, Howard KE		 (2019) BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains. Toxicol. Sci.
Perdomo-Celis F, et al.
Mouse over for full list
Perdomo-Celis F, Medina-Moreno S, Davis H, Bryant J, Zapata JC		 (2019) HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice. Pathogens 8(1)
Ito R, et al.
Mouse over for full list
Ito R, Maruoka S, Soda K, Katano I, Kawai K, Yagoto M, Hanazawa A, Takahashi T, Ogura T, Goto M, Takahashi R, Toyoshima S, Okayama Y, Izuhara K, Gon Y, Hashimoto S, Ito M, Nunomura S		 (2018) A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. JCI Insight 3(21)
Ito R, et al.
Mouse over for full list
Ito R, Nagai D, Igo N, Okuda Y, Sekine K, Ichimura E, Katano I, Mizushima T, Goto M, Ohnishi Y, Ito M, Okamoto K		 (2017) A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice. Toxicol. Lett. 281:152-157
Ito R, et al.
Mouse over for full list
Ito R, Takahashi T, Katano I, Kawai K, Kamisako T, Ogura T, Ida-Tanaka M, Suemizu H, Nunomura S, Ra C, Mori A, Aiso S, Ito M		 (2013) Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. J. Immunol. 191(6):2890-9
Immunology, Inflammation, Hypersensitivities, Humanized
Fukuchi Y, et al.
Mouse over for full list
Fukuchi Y, Miyakawa Y, Kobayashi K, Kuramochi T, Shimamura K, Tamaoki N, Nomura T, Ueyama Y, Ito M		 (1998) Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice. Leuk. Res. 22(9):837-43
Oncology, Leukemia, Humanized
Mamoru Ito, et al.
Mouse over for full list
Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi, Kazutomo Suzue, Mariko Kawahata, Kyoji Hioki, Yoshito Ueyama, Yoshio Koyanagi, Kazuo Sugamura, Kohichiro Tsuji, Toshio Heike, Tatsutoshi Nakahata		 (2002) NOD/SCID/γ nullc mouse: an excellent recipient mouse model for engraftment of human cells Blood 2002 100:3175-3182
Humanized
Close

Welcome! Tell us a little about yourself