Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
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Shu L, et al. Mouse over for full list |
(2023) | Bile exosomal miR-182/183-5p increases cholangiocarcinoma stemness and progression by targeting HPGD and increasing PGE2 generation. | Hepatology | |||
Jimbo K, et al. Mouse over for full list |
(2023) | Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia. | Leukemia 37(1):122-133 | |||
Gutierrez-Barbosa H, et al. Mouse over for full list |
(2023) | A Comparison of Lymphoid and Myeloid Cells Derived from Human Hematopoietic Stem Cells Xenografted into NOD-Derived Mouse Strains. | Microorganisms 11(6) | |||
Manni S, et al. Mouse over for full list |
(2023) | Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies. | Nat Commun 14(1):3423 | T And/Or B Cell Function, Oncology, Immunotherapy, Immuno-Oncology, Gene/Cell therapy | ||
Caruso S, et al. Mouse over for full list |
(2022) | Safe and effective off-the-shelf immunotherapy based on CAR.CD123-NK cells for the treatment of acute myeloid leukaemia. | J Hematol Oncol 15(1):163 | NK, Immunotherapy, Leukemia, Immuno-Oncology, Gene/Cell therapy | ||
Yang J, et al. Mouse over for full list |
(2022) | AL008 Enhances Myeloid Antitumor Function by Inhibiting SIRP? Signaling and Activating Fc Receptors. | J Immunol | |||
Ghoneim MA, et al. Mouse over for full list |
(2022) | Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice. | Stem Cell Res Ther 13(1):350 | Diabetes (Type 1), Stem Cells/Regenerative Medicine/Tissue Engineering, Induced Pluripotent Stem Cells (iPSCs) | ||
Dal Bello R, et al. Mouse over for full list |
(2022) | A multiparametric niche-like drug screening platform in acute myeloid leukemia. | Blood Cancer J 12(6):95 | Oncology, Leukemia, Patient Derived Xenograft (PDX) | ||
Albert DH, et al. Mouse over for full list |
(2022) | Co-clinical Modeling of the Activity of the BET Inhibitor Mivebresib (ABBV-075) in AML. | In Vivo 36(4):1615-1627 | Oncology, Leukemia, Patient Derived Xenograft (PDX) | ||
Bartels L, et al. Mouse over for full list |
(2019) | A Chemo-enzymatically Linked Bispecific Antibody Retargets T Cells to a Sialylated Epitope on CD43 in Acute Myeloid Leukemia. | Cancer Res 79(13):3372-3382 | Oncology, Leukemia, Therapeutic Efficacy Evaluation, Immuno-Oncology | ||
Roux B, et al. Mouse over for full list |
(2021) | Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. | Sci Transl Med 13(587) | |||
Pardieu B, et al. Mouse over for full list |
(2022) | Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia. | Leukemia 36(6):1585-1595 | |||
Lin KH, et al. Mouse over for full list |
(2020) | Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. | Nat Genet 52(4):408-417 | |||
Lin KH, et al. Mouse over for full list |
(2022) | P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia. | Nat Cancer | |||
Little CJ, et al. Mouse over for full list |
(2022) | Robust engraftment of fetal nonhuman primate CD34-positive cells in immune-deficient mice. | J Leukoc Biol | Immunology, Hematopoietic Stem Cell Engraftment, Infectious Disease | ||
Kumar S, et al. Mouse over for full list |
(2021) | Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models. | MAbs 13(1):1954136 | Immunology | ||
Vendramin R, et al. Mouse over for full list |
(2021) | Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma. | J Exp Med 218(9) | Oncology, Melanoma, Patient Derived Xenograft (PDX), Therapeutic Efficacy Evaluation | ||
Tran NT, et al. Mouse over for full list |
(2020) | CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia. | Mol Ther 28(12):2621-2634 | |||
Dai G, et al. Mouse over for full list |
(2021) | Toward a humanized mouse model of Pneumocystis pneumonia. | JCI Insight 6(2) | Infectious Disease | ||
Ito R, et al. Mouse over for full list |
(2020) | Bovine ?-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice. | Int Immunol | Immunology | ||
Maser IP, et al. Mouse over for full list |
(2020) | The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models. | Front Immunol 11:2082 | |||
Verma B, et al. Mouse over for full list |
(2020) | Establishment of Humanized Mice from Peripheral Blood Mononuclear Cells or Cord Blood CD34+ Hematopoietic Stem Cells for Immune-Oncology Studies Evaluating New Therapeutic Agents. | Curr Protoc Pharmacol 89(1):e77 | T And/Or B Cell Function, Humanized | ||
Cidado J, et al. Mouse over for full list |
(2019) | AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells. | Clin. Cancer Res. | |||
Ghosh S, et al. Mouse over for full list |
(2019) | TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade and . | Mol. Cancer Ther. 18(3):632-641 | |||
Wang Z, et al. Mouse over for full list |
(2019) | Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. | Sci Rep 9(1):1853 | |||
Weaver JL, et al. Mouse over for full list |
(2019) | BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains. | Toxicol. Sci. | |||
Perdomo-Celis F, et al. Mouse over for full list |
(2019) | HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice. | Pathogens 8(1) | |||
Ito R, et al. Mouse over for full list |
(2018) | A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. | JCI Insight 3(21) | |||
Ito R, et al. Mouse over for full list |
(2017) | A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice. | Toxicol. Lett. 281:152-157 | |||
Ito R, et al. Mouse over for full list |
(2013) | Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. | J. Immunol. 191(6):2890-9 | Immunology, Inflammation, Hypersensitivities, Humanized | ||
Fukuchi Y, et al. Mouse over for full list |
(1998) | Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice. | Leuk. Res. 22(9):837-43 | Oncology, Leukemia, Humanized | ||
Mamoru Ito, et al. Mouse over for full list |
(2002) | NOD/SCID/? nullc mouse: an excellent recipient mouse model for engraftment of human cells | Blood 2002 100:3175-3182 | Humanized |
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