NOG-EXL (hGM-CSF/hIL-3 NOG) Publications

NOG-EXL (hGM-CSF/hIL-3 NOG) Model Page

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Maser IP, et al.
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Maser IP, Hoves S, Bayer C, Heidkamp G, Nimmerjahn F, Eckmann J, Ries CH
(2020) The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models. Front Immunol 11:2082
Verma B, et al.
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Verma B, Wesa A
(2020) Establishment of Humanized Mice from Peripheral Blood Mononuclear Cells or Cord Blood CD34+ Hematopoietic Stem Cells for Immune-Oncology Studies Evaluating New Therapeutic Agents. Curr Protoc Pharmacol 89(1):e77
Cidado J, et al.
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Cidado J, Boiko S, Proia T, Ferguson D, Criscione SW, San Martin M, Pop-Damkov P, Su N, Roamio Franklin VN, Sekhar Reddy Chilamakuri C, D'Santos CS, Shao W, Saeh JC, Koch R, Weinstock DM, Zinda M, Fawell SE, Drew L
(2019) AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells. Clin. Cancer Res.
Ghosh S, et al.
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Ghosh S, Sharma G, Travers J, Kumar S, Choi J, Jun HT, Kehry M, Ramaswamy S, Jenkins D
(2019) TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade and . Mol. Cancer Ther. 18(3):632-641
Wang Z, et al.
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Wang Z, Sun K, Xiao Y, Feng B, Mikule K, Ma X, Feng N, Vellano CP, Federico L, Marszalek JR, Mills GB, Hanke J, Ramaswamy S, Wang J
(2019) Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. Sci Rep 9(1):1853
Weaver JL, et al.
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Weaver JL, Zadrozny LM, Gabrielson K, Semple KM, Shea KI, Howard KE
(2019) BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains. Toxicol. Sci.
Perdomo-Celis F, et al.
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Perdomo-Celis F, Medina-Moreno S, Davis H, Bryant J, Zapata JC
(2019) HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice. Pathogens 8(1)
Ito R, et al.
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Ito R, Maruoka S, Soda K, Katano I, Kawai K, Yagoto M, Hanazawa A, Takahashi T, Ogura T, Goto M, Takahashi R, Toyoshima S, Okayama Y, Izuhara K, Gon Y, Hashimoto S, Ito M, Nunomura S
(2018) A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis. JCI Insight 3(21)
Ito R, et al.
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Ito R, Nagai D, Igo N, Okuda Y, Sekine K, Ichimura E, Katano I, Mizushima T, Goto M, Ohnishi Y, Ito M, Okamoto K
(2017) A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice. Toxicol. Lett. 281:152-157
Ito R, et al.
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Ito R, Takahashi T, Katano I, Kawai K, Kamisako T, Ogura T, Ida-Tanaka M, Suemizu H, Nunomura S, Ra C, Mori A, Aiso S, Ito M
(2013) Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. J. Immunol. 191(6):2890-9
Immunology, Inflammation, Hypersensitivities, Humanized
Fukuchi Y, et al.
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Fukuchi Y, Miyakawa Y, Kobayashi K, Kuramochi T, Shimamura K, Tamaoki N, Nomura T, Ueyama Y, Ito M
(1998) Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice. Leuk. Res. 22(9):837-43
Oncology, Leukemia, Humanized
Mamoru Ito, et al.
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Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi, Kazutomo Suzue, Mariko Kawahata, Kyoji Hioki, Yoshito Ueyama, Yoshio Koyanagi, Kazuo Sugamura, Kohichiro Tsuji, Toshio Heike, Tatsutoshi Nakahata
(2002) NOD/SCID/γ nullc mouse: an excellent recipient mouse model for engraftment of human cells Blood 2002 100:3175-3182
Humanized