Taconic is the only commercial provider of germ-free C57BL/6 mice.
- C57BL/6, also called Black 6 or B6, is the most commonly used inbred strain. It is the preferred background strain for most genetically engineered mouse models.
- B6 is a versatile mouse strain. It is the preferred strain for diet-induced obesity studies. It is used in a number of autoimmune disease models, including experimental autoimmune encephalomyelitis (EAE) and the collagen-induced arthritis (CIA) model. For oncology, B6 has been used in syngeneic tumor models. It is also used in addiction, behavior, toxicology and many other research areas.
- The Taconic B6, C57BL/6NTac, is the substrain from which most B6 embryonic stem (ES) cells have been derived. The KOMP and MPC programs use C57BL/6NTac-derived ES cells.
- Immunology: Th1-biased
- More information and pricing is available on the Black 6 page.
: Germ Free Black 6
mice are available for immediate delivery. Study cohorts available of 100+.