Application Areas:
sPLA2
View:
Select One
- Description
- Price & Licensing
- Overview
- Genetics
- Guides & Publications
- Transit, Housing & Welfare
- Diet
Overview
Nomenclature: B6.SJL-Tg(PLA2G2A)703 N?+16
- Carries transgene for human Group II Phospholipase A2
- Develops alopecia, epidermal hyperplasia and enlarged sebacious glands
- Exhibits an increased susceptibility to LPS induced shock and atherosclerosis
- Useful to identify and evaluate new drug candidates for treatement of human inflammatory conditions and atherosclerosis.
Origin
This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 12 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.
Taconic’s Colony Management experts can design a plan to grow your colony faster.
Genetics
Guides & Publications
Initial Publication: Grass, D.S., Felkner, R.H., Chiang, M., Wallace, R.E., Nevalainen, T.J., Bennett, C.F., Swanson, M.E. Expression of Human Group II PLA2 in Transgenic Mice Results in Epidermal Hyperplasia in the Absence of Inflammatory Infiltrate, J Clin Invest., Vol. 97, No. 10, May 1996, pp. 2233-2241.
Transit, Housing & Welfare
Need more info? Click the live chat button or Contact Us
Diet
- Pricing
- Licensing
- Select my Health Standard
- Get Custom Pricing Guide
sPLA2
Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.
This model is sold under terms which grant perpetual use rights.
This model is sold under terms which grant perpetual use rights.
Select my Health Standard
Need help choosing the right Taconic Biosciences health standard for your research?
Use the Health Standard Selector to enter your exclusion list. The tool will tell you which health standards meet your requirements.
Get custom pricing guide
Schedule A Scientific Consultation
Connect directly with a member of our Scientific Solutions team who can help you select the most appropriate model and maximize your experimental success.
