sPLA₂

Genetic Background:

C57BL/6

Origin:

The sPLA₂ mouse was developed by Xenogen Biosciences, now Taconic. The model was created by microinjecting the human sPLA2 gene into C57BL/6 x SJL zygotes. The line was subsequently backcrossed to C57BL/6NTac.

Color:

Black

Species:

Mouse

Initial Publication:

Grass, D.S., Felkner, R.H., Chiang, M., Wallace, R.E., Nevalainen, T.J., Bennett, C.F., Swanson, M.E. Expression of Human Group II PLA2 in Transgenic Mice Results in Epidermal Hyperplasia in the Absence of Inflammatory Infiltrate, J Clin Invest., Vol. 97, No. 10, May 1996, pp. 2233-2241.

Animal Diet:

NIH #31M Rodent Diet

To purchase this EZcohort model, sign the Terms of Sale (choose from the list below) and email it directly to legal@taconic.com:

This model is sold under terms which grant perpetual use rights.