DBA/1 Inbred Mouse Model
Alert: This model will no longer be available for sale by weight effective November 1, 2019.

  • Model #
  • Genotype
  • Nomenclature
  • DBA1BO-F
    DBA/1JBomTac
  • DBA1BO-M
    DBA/1JBomTac
  • Suitable general-purpose research model for immunology and inflammation research
  • Widely used as a model of autoimmunity, especially collagen-induced arthritis
  • High incidence of mammary tumors

Origin:

The DBA inbred model was developed by Dr. C. C. Little of the Jackson Laboratory in 1909. The DBA/1 substrain was generated in 1929. M&B A/S (now Taconic Europe) received stock from Jackson Laboratory in 1993. The mice were derived by embryo transfer in 2005 at Taconic US.

Genetics:

  • Strain Profile: Anpepb, Car2a, Es1b, Es3c, Esdb, Gpi1a, Got2b, Hbbd, Idh1b, Mod1a, Mup1a, Pgm1b, Trfb
  • Immunology: H2q
  • Other: Cd5a, Cd8aa, Cd8bb, Hc1, Thy-1b

Coat Color Loci:

a, Tyrp1b, Myo5ad

Color:

Dilute Brown Non-Agouti

Species:

Mouse


Taconic cannot routinely accept orders by weight for this model due to colony size. Please inquire for options if weight is critical for your experiment.

n = 250 per sex at MPF health standard from all global colonies.
High and Low represent mean +/- 2 standard deviations.
Based on sample size the charts above represent ~90% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves.
Growth charts are provided only as a guide.

Customize this chart by clicking the legend elements, then explore download options by hovering your cursor over the down arrow to the right of the chart title.
Average litter size: 8
Lifespan: Lifespan of males is (430 days) but life span of females is long (750 days).

Collagen Induced Arthritis in DBA1 Mice