Tnk1

Constitutive Knockout

Cryopreserved Model
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This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF1938
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    MGI:1930958

Gene Description: tyrosine kinase, non-receptor, 1

Synonyms: Kos1, Tnk1a, Tnk1b

Gene Family:

Kinase

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_031880

Mutation Type:

Targeted

Species:

Mouse


The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) Mutant Mice, heterozygous for the Selected Mutation, including at least one (1) breeding pair on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data

Business TypePrice per LinePrice per Line for Comprehensive Phenotype Data
For Profit (Commercial)$20,000*
€17,000*		$10,000*
€8,500*
Nonprofit$15,000*
€12,750*		$8,000*
€6,800*
Basic Phenotype Package: $5,000 (€4,200)
*A 10% discount will be applied if the model is bred and managed by Taconic's team of breeding experts.
*A 10% discount will be applied to the purchase of more than one line per fiscal year.

KOR models are invoiced upon shipment. Once orders are placed, full purchase price will be applied if order is cancelled.

Fees for Taconic Transit Cages and freight are in addition to the price above.