Tnfrsf19

Gene Family:

Membrane

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_013869

Mutation Type:

Trapped

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/10585776 http://www.ncbi.nlm.nih.gov/pubmed/11239407 http://www.ncbi.nlm.nih.gov/pubmed/12466851 http://www.ncbi.nlm.nih.gov/pubmed/12702649 http://www.ncbi.nlm.nih.gov/pubmed/12781685 http://www.ncbi.nlm.nih.gov/pubmed/12763585 http://www.ncbi.nlm.nih.gov/pubmed/12972005 http://www.ncbi.nlm.nih.gov/pubmed/14699584 http://www.ncbi.nlm.nih.gov/pubmed/14966863 http://www.ncbi.nlm.nih.gov/pubmed/15694321 http://www.ncbi.nlm.nih.gov/pubmed/15694322 http://www.ncbi.nlm.nih.gov/pubmed/16481354 http://www.ncbi.nlm.nih.gov/pubmed/16820005 http://www.ncbi.nlm.nih.gov/pubmed/16782087 http://www.ncbi.nlm.nih.gov/pubmed/16870160 http://www.ncbi.nlm.nih.gov/pubmed/17470639 http://www.ncbi.nlm.nih.gov/pubmed/17278136 http://www.ncbi.nlm.nih.gov/pubmed/10809768 http://www.ncbi.nlm.nih.gov/pubmed/16141072 http://www.ncbi.nlm.nih.gov/pubmed/17095659 http://www.ncbi.nlm.nih.gov/pubmed/17362907 http://www.ncbi.nlm.nih.gov/pubmed/16524929 http://www.ncbi.nlm.nih.gov/pubmed/10764796

 

The knockout models are designed to be null alleles. Due to compensatory genetic mechanisms, knockout status cannot be guaranteed and will have to be confirmed by the customer. Some validation data may be already available – please inquire for more details.

The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyr^c-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyr^c-Brd background.