Sirt5

Gene Family:

Enzyme

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_178848

Mutation Type:

Trapped

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/11217851 http://www.ncbi.nlm.nih.gov/pubmed/12466851 http://www.ncbi.nlm.nih.gov/pubmed/17923681 http://www.ncbi.nlm.nih.gov/pubmed/18054327

 

The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyr^c-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyr^c-Brd background.