Scarb1

Gene Family:

Membrane

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_016741

Mutation Type:

Targeted

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/8798380 http://www.ncbi.nlm.nih.gov/pubmed/8753864 http://www.ncbi.nlm.nih.gov/pubmed/8969220 http://www.ncbi.nlm.nih.gov/pubmed/7520436 http://www.ncbi.nlm.nih.gov/pubmed/9148942 http://www.ncbi.nlm.nih.gov/pubmed/9163428 http://www.ncbi.nlm.nih.gov/pubmed/10438476 http://www.ncbi.nlm.nih.gov/pubmed/9407090 http://www.ncbi.nlm.nih.gov/pubmed/9539787 http://www.ncbi.nlm.nih.gov/pubmed/9974430 http://www.ncbi.nlm.nih.gov/pubmed/10066776 http://www.ncbi.nlm.nih.gov/pubmed/10224152 http://www.ncbi.nlm.nih.gov/pubmed/10478838 http://www.ncbi.nlm.nih.gov/pubmed/10518574 http://www.ncbi.nlm.nih.gov/pubmed/10725249 http://www.ncbi.nlm.nih.gov/pubmed/10712397 http://www.ncbi.nlm.nih.gov/pubmed/10772649 http://www.ncbi.nlm.nih.gov/pubmed/10764675 http://www.ncbi.nlm.nih.gov/pubmed/10751392 http://www.ncbi.nlm.nih.gov/pubmed/10884299 http://www.ncbi.nlm.nih.gov/pubmed/11217851 http://www.ncbi.nlm.nih.gov/pubmed/11108726 http://www.ncbi.nlm.nih.gov/pubmed/11208732 http://www.ncbi.nlm.nih.gov/pubmed/11714849 http://www.ncbi.nlm.nih.gov/pubmed/11733567 http://www.ncbi.nlm.nih.gov/pubmed/11861300 http://www.ncbi.nlm.nih.gov/pubmed/11923102 http://www.ncbi.nlm.nih.gov/pubmed/12006675 http://www.ncbi.nlm.nih.gov/pubmed/12466851 http://www.ncbi.nlm.nih.gov/pubmed/12771386 http://www.ncbi.nlm.nih.gov/pubmed/12639961 http://www.ncbi.nlm.nih.gov/pubmed/12805272 http://www.ncbi.nlm.nih.gov/pubmed/14643015 http://www.ncbi.nlm.nih.gov/pubmed/14729860 http://www.ncbi.nlm.nih.gov/pubmed/14726490 http://www.ncbi.nlm.nih.gov/pubmed/14993241 http://www.ncbi.nlm.nih.gov/pubmed/14528013 http://www.ncbi.nlm.nih.gov/pubmed/15331403 http://www.ncbi.nlm.nih.gov/pubmed/15265030 http://www.ncbi.nlm.nih.gov/pubmed/15533830 http://www.ncbi.nlm.nih.gov/pubmed/15314100 http://www.ncbi.nlm.nih.gov/pubmed/15866482 http://www.ncbi.nlm.nih.gov/pubmed/16200214 http://www.ncbi.nlm.nih.gov/pubmed/16263415 http://www.ncbi.nlm.nih.gov/pubmed/10430941 http://www.ncbi.nlm.nih.gov/pubmed/16498401 http://www.ncbi.nlm.nih.gov/pubmed/16600185 http://www.ncbi.nlm.nih.gov/pubmed/16461760 http://www.ncbi.nlm.nih.gov/pubmed/11861414 http://www.ncbi.nlm.nih.gov/pubmed/15692099 http://www.ncbi.nlm.nih.gov/pubmed/16421100 http://www.ncbi.nlm.nih.gov/pubmed/12117558 http://www.ncbi.nlm.nih.gov/pubmed/15967843 http://www.ncbi.nlm.nih.gov/pubmed/16964311 http://www.ncbi.nlm.nih.gov/pubmed/10559220 http://www.ncbi.nlm.nih.gov/pubmed/16867981 http://www.ncbi.nlm.nih.gov/pubmed/16339487 http://www.ncbi.nlm.nih.gov/pubmed/16574909 http://www.ncbi.nlm.nih.gov/pubmed/17399905 http://www.ncbi.nlm.nih.gov/pubmed/17272829 http://www.ncbi.nlm.nih.gov/pubmed/17389516 http://www.ncbi.nlm.nih.gov/pubmed/17657311 http://www.ncbi.nlm.nih.gov/pubmed/14970197 http://www.ncbi.nlm.nih.gov/pubmed/16624615 http://www.ncbi.nlm.nih.gov/pubmed/17442616 http://www.ncbi.nlm.nih.gov/pubmed/17761631 http://www.ncbi.nlm.nih.gov/pubmed/16269665 http://www.ncbi.nlm.nih.gov/pubmed/17960026 http://www.ncbi.nlm.nih.gov/pubmed/17954936 http://www.ncbi.nlm.nih.gov/pubmed/18064300 http://www.ncbi.nlm.nih.gov/pubmed/18093975 http://www.ncbi.nlm.nih.gov/pubmed/18175806 http://www.ncbi.nlm.nih.gov/pubmed/17717299 http://www.ncbi.nlm.nih.gov/pubmed/18342019 http://www.ncbi.nlm.nih.gov/pubmed/8560269 http://www.ncbi.nlm.nih.gov/pubmed/9254074 http://www.ncbi.nlm.nih.gov/pubmed/9356497 http://www.ncbi.nlm.nih.gov/pubmed/10482304 http://www.ncbi.nlm.nih.gov/pubmed/10680042 http://www.ncbi.nlm.nih.gov/pubmed/9421400 http://www.ncbi.nlm.nih.gov/pubmed/11181745 http://www.ncbi.nlm.nih.gov/pubmed/11278646 http://www.ncbi.nlm.nih.gov/pubmed/11880569 http://www.ncbi.nlm.nih.gov/pubmed/11907136 http://www.ncbi.nlm.nih.gov/pubmed/12439624 http://www.ncbi.nlm.nih.gov/pubmed/15105424 http://www.ncbi.nlm.nih.gov/pubmed/15654132 http://www.ncbi.nlm.nih.gov/pubmed/16141072 http://www.ncbi.nlm.nih.gov/pubmed/15749707 http://www.ncbi.nlm.nih.gov/pubmed/14581413 http://www.ncbi.nlm.nih.gov/pubmed/11116096 http://www.ncbi.nlm.nih.gov/pubmed/17071747 http://www.ncbi.nlm.nih.gov/pubmed/16971476 http://www.ncbi.nlm.nih.gov/pubmed/17148552 http://www.ncbi.nlm.nih.gov/pubmed/17299204 http://www.ncbi.nlm.nih.gov/pubmed/16397139 http://www.ncbi.nlm.nih.gov/pubmed/17272756 http://www.ncbi.nlm.nih.gov/pubmed/18204096 http://www.ncbi.nlm.nih.gov/pubmed/18332148 http://www.ncbi.nlm.nih.gov/pubmed/18245842 http://www.ncbi.nlm.nih.gov/pubmed/18340042 http://www.ncbi.nlm.nih.gov/pubmed/15944188 http://www.ncbi.nlm.nih.gov/pubmed/9383292 http://www.ncbi.nlm.nih.gov/pubmed/15539616

 

The knockout models are designed to be null alleles. Due to compensatory genetic mechanisms, knockout status cannot be guaranteed and will have to be confirmed by the customer. Some validation data may be already available – please inquire for more details.

The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyr^c-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyr^c-Brd background.