Constitutive Knockout

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF3246
Gene Description: peroxiredoxin 1

Synonyms: macrophage 23kDa stress protein, macrophase stress protein 22kDa, MSP23, OSF-3, osteoblast specific factor 3, PAG, Paga, prx1, PrxI, Prx I, Tdpx2, TDX2, thioredoxin dependent peroxide reductase 2, Trx dependent peroxide reductase 2

Gene Family:


Genetic Background:


Gene Accession Number:


Mutation Type:




The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) Mutant Mice, heterozygous for the Selected Mutation, including at least one (1) breeding pair on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data
Business TypePrice per LinePrice per Line for Comprehensive Phenotype Data
For Profit (Commercial)$20,000*
Basic Phenotype Package: $5,000 (€4,200)
*A 10% discount will be applied if the model is bred and managed by Taconic's team of breeding experts.
*A 10% discount will be applied to the purchase of more than one line per fiscal year.