Chrna5

Constitutive Knockout

Cryopreserved Model
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This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF1583
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    MGI:87889

Gene Description: cholinergic receptor, nicotinic, alpha polypeptide 5

Synonyms: Acra5, Acra-5

Gene Family:

Ion Channel

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_176844

Mutation Type:

Targeted

Species:

Mouse


The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) mutant mice, heterozygous for the selected mutation on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data

Business TypePrice per Line $/€Price per Line for Comprehensive Phenotype Data $/€
For Profit (Commercial)$20,000
€18,200		$10,000
€9,100
Nonprofit$15,000
€13,650		$8,000
€7,280
Basic Phenotype Package: $5,000/€4,550

KOR models are invoiced upon shipment. Once orders are placed, full purchase price will be applied if order is cancelled.

Fees for Taconic Transit Cages™ and freight are in addition to the price above.