Cacna1g

Gene Family:

Channel

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_009783

Mutation Type:

Targeted

Species:

Mouse

The knockout models are designed to be null alleles. Due to compensatory genetic mechanisms, knockout status cannot be guaranteed and will have to be confirmed by the customer. Some validation data may be already available – please inquire for more details.

Please contact Taconic to discuss your usage needs.

The CIEA NOG mouse® is produced and distributed under license rights to the following patents and trademarks:

Japanese Patent No. 3,753,321

US Patent No. 7,145,055; 5,464,764; 5,487,992; 5,627,059; 5,631,153; 5,789,215; 6,204,061; 6,653,113; 6,689,610
EU Patent No. 1,338,198

Japanese Trademark Reg. No. 4,823,423

US Trademark Reg. No. 3,118,040

EU Trademark Reg. No. 3,736,758

The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyr^c-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyr^c-Brd background.