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NIH Nude

SPONTANEOUS MUTANT T-CELL DEFICIENT RATS

Model Number	Zygosity	Nomenclature
NIHRNU-F	Homozygous	NTac:NIH-Whn
NIHRNU-M	Homozygous	NTac:NIH-Whn
NIHRNU-F	Heterozygous	NTac:NIH-Whn
NIHRNU-M	Heterozygous	NTac:NIH-Whn

Model Description

Exhibits deficient T cell activity with lymph nodes and Peyers patches showing lymphocyte depletion in T-lymphocyte dependent regions
In this outbred immunodeficient model the vibrissae are present in the homozygous nude rat but bent with some short hairs on the head and occasionally on the rest of the body
At later ages some hair growth occurs but rats become hairless again within a few weeks
Skin of homozygous rat is generally pigmented, but occasionally an albino rat is seen

Origin: The NIH nude Spontaneous mutant model was developed by NIH in 1979-1980 by intercrossing eight strains of rats. Taconic received stock from NIH Animal Genetic Resource in 1981. The rats were derived by hysterectomy in 1987 and again in 1998. Animals are randomly bred at Taconic without selection for coat color or pigmentation.

Color: Various

Genetics:

Animal Diet: NIH #31M Rodent Diet

Growth Chart

Price Table

NIHRNU (in U.S. Dollars)

Quantity	Age (weeks)	Male	Female
1-49	4	$135.20	$140.40
1-49	5 to 8	$161.60	$167.40
1-49	9 to 12	$191.10	$197.90
50+	4	$124.40	$129.10
50+	5 to 8	$148.70	$154.00
50+	9 to 12	$175.90	$182.10

Untimed Pregnant	$666.20
Female with Natural Litter	$1,080.00
Retired Breeder, females will be heterozygous and males will be homozygous	$173.50
Animals over 12 weeks of age, call for pricing.