HIV in Humanized Mice

Tuesday, September 13, 2016, 11 a.m. ET

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Advancing Microbiome Research: Microbiome & Disease

Thursday, November 3, 2016
Potomac, MD

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  • Animal Model Quality: Transportation and Environmental Factors

    What are the most important factors in assessing the quality of an animal model? In Part I, we discussed two of the four quality considerations for using laboratory mice: health and genetics. To recap: It's important to understand the different health standards when assessing an... Read more

  • A Successful Breeding Plan in Five Steps

    "It's just breeding... right?" You may want to carry out large cohort studies within the next 4-6 months, or to quickly recover a cryopreserved line from your collaborator to cross with your own knockout line. How difficult can it be? The temptation of getting there... Read more

  • Does the Microbiome Affect Behavior in Germ-free Mice?

    There is growing evidence that the microbiome, that collection of all the microorganisms which inhabit an individual, can affect cognition and behavior. This has been termed the microbiota-gut-brain axis. Germ-free mice are a critical tool in studies investigating this connection, and they have been shown... Read more

  • Quality Considerations in the Use of Animal Models

    Which elements of quality should you consider when conducting a study with animal models? Let's start with the definition of quality from Merriam-Webster: Quality [qual-i-ty] noun How good or bad something is. A characteristic or feature that someone or something has, something that can be... Read more

  • Activated Soy Affects Weight Gain and Microbiome in Obese Mice

    Researchers from the USDA, Tulane, LSU, and Microbiome Therapeutics have linked soy pod fiber to significantly reduced weight gain in obese mice. (Source: Obesity. 2016 Jan;24(1):87-95.) The study looked at activated soy pod fiber as a dietary intervention in mice fed an obesogenic diet. Two... Read more

  • Congenic Mice: What's in a Name?

    Researchers unfamiliar with mouse genetics can be confused by complex strain nomenclature, leaving them unsure how to select controls for a particular test strain. The nomenclature of congenic mice records a wealth of useful information, including both donor and recipient strains and mutations of interest.... Read more

  • Q&A: Diet Induced Obese Mice

    Taconic's Product Manager, Jennifer Phelan recently presented a webinar on diet-induced obesity (DIO) in mouse models and the production of obese mice, including important factors in housing and husbandry. Many of your questions went unanswered due to time constraints, so we present those additional questions... Read more

  • Guidelines for Use of Humanized Mice in IBD Drug Discovery

    Inflammatory Bowel Disease (IBD) is a chronic immunologically mediated disease with no known cure. Can humanized mice speed up IBD drug discovery, bringing relief to the estimated 1.4 million Americans with this difficult condition? To support IBD research, Taconic hosted a webinar by TransCure BioServices... Read more