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Rapid Generation of Mouse and Rat Mutants by CRISPR/Cas in One-Cell Embryos

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  • Why would you want a Black 6 mouse that isn’t black?

    Taconic Biosciences introduced two new B6 albino models in late 2012 and early 2013. The B6 Albino A++ (model 11227) and the B6 Albino (model 11971) were generated at Taconic’s Cologne, Germany, site via gene targeting technology. These models represent the first albino B6 models available on the C57BL/6NTac... Read More

  • Promise and Potential of Humanized Mouse Models

    In a recently published article in Lab Animal Europe, Taconic Bioscience's Dr. Leon Hall, Senior Director, Global Scientific Development and Translational Discovery Services, discusses the promise and potential of humanized mouse models. The mouse remains one of the most commonly used models for biomedical... Read More

  • How Lab Animal Health Standards Are Evolving - Six Pillars That Can Help You Choose the Right Approach

    In a recently published article in GEN Exclusives, Taconic Bioscience's Dr. Jeff Lohmiller, VP of Quality Systems, describes the critical role health standards have always played in the use of research lab animals. He explains that evolving industry needs and advancements in research and the animals... Read More


    Taconic Biosciences is partnering again with the Rare Genomics Institute (RGI) to support the 2015 Rare Disease Science Challenge: Be HEARD (Helping Empower and Accelerate Research Discoveries). As a sponsor of the Rare Disease Challenge in 2014, Taconic donated custom generation of a genetically engineered... Watch a video from the 2014 winner

  • hGM-CSF/hIL3-NOG mouse Questions – We have the answers!

    Taconic recently hosted a webinar titled The hGM-CSF/hIL3-NOG mouse: Enhanced differentiation of multiple human cell lineages in humanized mice, presented by Dr. Takeshi Takahashi.  Dr. Takahashi, Chief Scientist in the Immunology Laboratory at the Central Institute for Experimental Animals (CIEA), introduced... Read more

  • Humanization 101 Questions - We Have The Answers!

    Taconic recently hosted a webinar titled Cell and Tissue Humanized Mice 101, presented by Dr. Leon Hall.  Dr. Hall, Taconic’s Sr. Director, Global Scientific Development and Translational Discovery Services, introduced key humanized mouse models and showed data from new models currently under development. ... Read more

  • Immune System Humanized Mice: Enabling a New Frontier in Drug Discovery

    The immune system is a complex orchestration of blood and tissue cells that protect us from pathogenic invaders like bacteria, and viruses.  Our knowledge of the immune system has grown exponentially over the past twenty five years, with a multitude of discoveries originating from studies in wild type... Read more

  • GEMS Risk Management

    When our computers crash, we immediately panic, wondering if our data will be lost forever. We recall how often our Information Technology department reminds us to back up our data and how often we ignore this suggestion. Now, how about rodent lines? Who reminds us to back up our unique genetically engineered... Read more

  • New Publications Suggest Gut Microbiota Play a Key Role in Disease Progression

    Two recent publications provide further evidence that the gut microbiota play a key role in disease progression, and additionally, the valuable role that germ free mice can play in helping to elucidate those key roles. In each study summarized below, mice with conventional gut flora and germ free mice... Read more

  • Taconic Brings Together the Scientific Community for Discussion of Humanized Mouse Models

    Taconic Biosciences recently organized and hosted a symposium on "The NOG platform: advanced models for immune system humanization and oncology research" in the Boston area. The half-day event gathered experts from the US and Japan to discuss the impact of the NOG mouse and related models in biomedical... Read more