HIV in Humanized Mice

Tuesday, September 13, 2016, 11 a.m. ET

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Intro to the Microbiome

Thursday, August 25, 2016, 11 a.m. ET

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  • Activated Soy Affects Weight Gain and Microbiome in Obese Mice

    Researchers from the USDA, Tulane, LSU, and Microbiome Therapeutics have linked soy pod fiber to significantly reduced weight gain in obese mice. (Source: Obesity. 2016 Jan;24(1):87-95.) The study looked at activated soy pod fiber as a dietary intervention in mice fed an obesogenic diet. Two... Read more

  • Congenic Mice: What's in a Name?

    Researchers unfamiliar with mouse genetics can be confused by complex strain nomenclature, leaving them unsure how to select controls for a particular test strain. The nomenclature of congenic mice records a wealth of useful information, including both donor and recipient strains and mutations of interest.... Read more

  • Q&A: Diet Induced Obese Mice

    Taconic's Product Manager, Jennifer Phelan recently presented a webinar on diet-induced obesity (DIO) in mouse models and the production of obese mice, including important factors in housing and husbandry. Many of your questions went unanswered due to time constraints, so we present those additional questions... Read more

  • Guidelines for Use of Humanized Mice in IBD Drug Discovery

    Inflammatory Bowel Disease (IBD) is a chronic immunologically mediated disease with no known cure. Can humanized mice speed up IBD drug discovery, bringing relief to the estimated 1.4 million Americans with this difficult condition? To support IBD research, Taconic hosted a webinar by TransCure BioServices... Read more

  • Cancer Drug Suggests Promising Alzheimer's Treatment

    In a 2015 report, a team of scientist from the Weizmann Institute of Science provided compelling evidence that boosting the immune response in the brain (as opposed to suppressing it) might be a promising avenue for Alzheimer's research. In an extension of its initial findings,... Read more

  • C57BL/6 DIO 101: Best Practices for Diet Induced Obesity in Mice

    A DIO (diet induced obese) mouse is a C57BL/6 - "Black 6" - mouse which has been made obese through conditioning with a special diet. These diets tend to be high in fat, however there are sometimes other modifications made such as added sugar and... Read more

  • Are Humanized Mice the Future of Oncology Models?

    Oncologists are up against the limits of cell cultures and xenografts in applied research. Are humanized mice the solution? In an article discussing the challenge of tumor heterogeneity, Drug Discovery News (DDN) laid out several factors which contribute to heterogeneity and which complicate the clinical... Read more

  • The Dirty Future of Immunology Animal Models

    When discrepancies in immune response arise between animal models and humans, some investigators are quick to question the adequacy of laboratory mice as a proxy for human subjects. Two collaborative studies, published in Nature and Cell Host & Microbe, suggest that animal model microbiome and... Read more