Advancing Microbiome Research: Microbiome & Disease

Thursday, November 3, 2016
Potomac, MD

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Immuno-Oncology in Humanized Mice: cell line growth and patient-derived xenograft models successfully engrafted in the huNOG

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  • Society for Neuroscience 2016 Abstracts - By the Numbers

    In a little less than a month, 30,000 scientists will gather in San Diego for Society for Neuroscience 2016 Annual Meeting. Over 15,000 abstracts have been accepted for presentations in symposia, mini-symposia, and posters. There will be more than 100 satellite events being held in... Read more

  • FAQ: Animal Models for Microbiome Research

    The microbiome is emerging as an important factor in disease development, progression and prevention. Researchers are trying to harness the microbiome and its role in immune response for therapeutic purposes. Gnotobiotic and germ-free mice will play a pivotal role for researchers. To better serve the... Read more

  • Fourth Quarter Microbiome Conferences Roundup

    Are you looking for a good scientific microbiome research symposium? Over the next three months, you have six exciting microbiome conferences from which to choose. Symposium Date Location World Congress on Targeting Microbiota 2016 10/17/16 to 10/19/16 Paris, France Gut Microbiome 2016 - An International... Read more

  • When Are Nude Rats Better?

    Researchers have a wide range of immunodeficient mouse models from which to choose a suitable experimental host, including nudes, scids, Rag2 knockouts, and super immunodeficient models such as the CIEA NOG mouse®. Each model offers different strengths and weaknesses, but one commonality is that they... Read more

  • Variations within Outbred Strains: Know Your Strains and Stocks

    The Sprague Dawley® (SD) rat is one of the most popular outbred stocks, with application across many therapeutic areas as well as ADMET studies. The SD is an outbred stock, meaning that there is genetic variation within the stock, and each individual varies in genetic... Read more

  • Improving Lives by Modeling Rare Genetic Disorders

    Relief for patients with rare genetic disorders are often out of reach, due to the expense of developing genetically engineered animal models. That's why the Rare Genomics Institute, Taconic Biosciences, and Jonah's Just Begun came together to develop and characterize a model of Sanfilippo Syndrome.... Read more

  • What's in a Name? Origins of the CIEA NOG mouse®

    The CIEA NOG mouse® is often referred to as an ideal mouse for engraftment of foreign (especially human) cells. The high rates of engraftment make NOG mice a preferred choice for patient-derived xenografts and humanized immune system mice studies. What special properties make the NOG... Read more

  • Modeling Proprioception

    NPR recently published "How A 'Sixth Sense' Helps Simone Biles Fly, And The Rest Of Us Walk", that explored proprioception - the sense of the relative position of neighboring parts of the body - with a story on children with a rare mutation in a... Read more