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The Ultimate Xenograft Host Comparison Guide

February 25, 2016, 11 a.m. ET
March 1, 2016, 8 a.m. ET

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  • Aging and the Immune Response to Influenza Infection

    In a recent presentation at Taconic Biosciences, Dr. Laura Haynes, Professor at the Center on Aging, Department of Immunology at the UCONN School of Medicine, discussed how aging affects immunological responses. Her lab utilizes an influenza virus infection mouse model. Aging and Immunology Aging... Read more

  • Discover huNOG-EXL: Extending the Limits of Engrafted Human Immune System Models

    Taconic Biosciences' Dr. Michael Seiler, Associate Director, Genetically Engineered Models Design and Precision Research Models, presented an e-seminar featuring some of the latest applications of Taconic's newest extended lineage NOG model, huNOG-EXL, designed for applications in allergy, inflammation and immuno-oncology research. Learn more about... Read more

  • The NOG platform expands - new human cytokine transgenics

    Dozens of papers have demonstrated the utility of the CIEA NOG mouse® for human immune system engraftment. Several systems are commonly used for human immune engraftment, each with their own advantages and disadvantages. Human hematopoietic stem cells can be engrafted to generate huNOG mice, which... Read more

  • Book Review: Humanized Mice for HIV Research

    HIV researchers have been challenged in finding a suitable small animal model, as rodents such as mice and rats cannot be infected by HIV. Existing animal models such as chimpanzees are not ideal as they are expensive, more challenging to work with and have a... Read more

  • What do President Jimmy Carter and Taconic's huNOG mice have in common?

    In a press conference on August 20, 2015, former US President Jimmy Carter announced that he was diagnosed with stage four, metastatic melanoma. During the press conference President Carter revealed that the cancer had spread to his liver and brain, and while inoperable, he... Read more

  • Additional Mouse Models Added To The Cancer Research Technology Repository

    Taconic Biosciences has recently added an additional 6 mouse lines to the Cancer Research Technology (CRT) Repository as part of the Emerging Models collection. The CRT repository provides academic and non-profit researchers with worldwide access to multiple genetically engineered mouse models that may be... Read more

  • What do CRISPR, the number 62 and pigs have in common?

    The American Transplant Foundation reports that there are currently 123,000 people in the United States on a waiting list for an organ transplant. On average, 21 people die every day from the lack of available organs for transplant. Extending that number out to the worldwide... Read more

  • scid mutants or Rag2 knockouts - Which immunodeficient model is best for your study?

    Mice with compromised immune systems are invaluable research tools. Starting with the discovery of athymic nude mice in the 1960's, the portfolio of immunodeficient rodents has grown significantly. Although these models are used quite widely, not all researchers understand their intrinsic characteristics and how those... Read more