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Black 6

TRADITIONAL INBRED MICE

C57BL/6NTac Background

Model Number	Zygosity	Nomenclature
B6-F		C57BL/6NTac
B6-M		C57BL/6NTac

Model Description

The most widely used inbred as the genetic background for transgenic and mutant mice
Popular in research applications of oncology, immunology and toxicology
Now available at the Restricted Flora health profile in addition to the Murine Pathogen Free health Profile
Off the shelf inventory of Diet Induced Obese male B6 mice and aged male B6 mice now available.

Origin: C57BL/6 litters were received in 1991 at F151 from the NIH Animal Genetic Resource. Cesarean derived in 1991 at Taconic, a foundation colony is maintained in gnotobiotic isolators. Origin is as follows: to NIH in 1951 from Jax at F32; to Jax in 1948 from Hall.

Color: Black

Coat Color Loci: a

Genetics:

Strain Profile: Acy1^f, Alad^b, Car2^a, Cas1^g, Cd5^b, Cd72^b, Cd8a^b, Cd8b1^b, Ce2^a, Es1^a, Es3^a, Esd^a, Ggc1^b, Gpi1^b, Gus-s^b, H6pd1^b, Hba^a, Hbb^s, Hc¹, Idh1^a, Mod1^b, Mup1^b, Pep3^a, Pgm1^a, Trf^b
Immunology: H2^b, Ptprc^b, Thy1^b, H2-T18^b

Animal Diet: NIH #31M Rodent Diet

Growth Chart

Phenotyping

B6 Phenotyping procedures and report (2004)

Phenotypic Data Assays: Irwin (B6 on standard diet); Startle and Pre-pulse Inhibition (B6 on standard diet); Open Field (B6 on standard diet); Rotarod (B6 on standard diet); Hot Plate (B6 on standard diet); Body Weight (B6 on high fat diet); Blood Pressure and Heart Rate (B6 on high fat diet); Metabolism and Activity in the Comprehensive Cage Monitoring System (B6 on high fat diet); Oral Glucose Tolerance Test (B6 on high fat diet); mBSA-Induced Delayed Type Hypersensitivity (DTH) (B6 on standard diet; Ovalbumin-Induced In Vivo Antibody Production (B6 on standard diet); Hematology (B6 on standard diet); FACS Analysis of Splenocytes (B6 on standard diet); Automated Clinical Chemistry Analysis (ACCA) (B6 on standard diet)

Price Table

B6 (in U.S. Dollars)

Quantity	Age (weeks)	Male	Female
1-199	3 to 4	$17.30	$18.70
1-199	5 to 6	$20.40	$20.70
1-199	7 to 9	$22.60	$22.40
1-199	10 to 12	$31.50	$31.50
200+	3 to 4	$16.00	$17.20
200+	5 to 6	$18.90	$19.20
200+	7 to 9	$20.80	$20.60
200+	10 to 12	$29.00	$28.20