DBA/1

Inbred

DBA/1 Inbred Mouse Model

  • Model #
  • Genotype
  • Nomenclature
  • DBA1BO-F
    DBA/1JBomTac
  • DBA1BO-M
    DBA/1JBomTac
  • Suitable general-purpose research model for immunology and inflammation research
  • Widely used as a model of autoimmunity, especially collagen-induced arthritis
  • High incidence of mammary tumors

Origin:

The DBA inbred model was developed by Dr. C. C. Little of the Jackson Laboratory in 1909. The DBA/1 substrain was generated in 1929. M&B A/S (now Taconic Europe) received stock from Jackson Laboratory in 1993. The mice were derived by embryo transfer in 2005 at Taconic US.


Genetics:

  • Strain Profile: Anpepb, Car2a, Es1b, Es3c, Esdb, Gpi1a, Got2b, Hbbd, Idh1b, Mod1a, Mup1a, Pgm1b, Trfb
  • Immunology: H2q
  • Other: Cd5a, Cd8aa, Cd8bb, Hc1, Thy-1b

Coat Color Loci:

a, Tyrp1b, Myo5ad

Color:

Dilute Brown Non-Agouti

Species:

Mouse


For some applications, weight may be critical. For orders where weight is critical, please place orders by weight, not by age. Taconic can accept orders by weight for this model. A minimum 3 gram span is required. All weights are weights at time of packing. Mice and rats can lose weight in transit. Orders for specific weight spans will be assessed a nominal fee. More detail on weight order policies is available.

n = 250 per sex at MPF health standard from all global colonies.
High and Low represent mean +/- 2 standard deviations.
Based on sample size the charts above represent ~90% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves.
Growth charts are provided only as a guide, if a specific weight criteria is needed please order animals by weight.

Customize this chart by clicking the legend elements, then explore download options by hovering your cursor over the down arrow to the right of the chart title.
Average litter size: 8
Lifespan: Lifespan of males is (430 days) but life span of females is long (750 days).

Collagen Induced Arthritis in DBA1 Mice