Regulatory T cells (Tregs) are a critical component of the immune system for regulating inflammatory responses. In the context of immune-mediated diseases, such as cancer or graft-versus-host disease (GvHD), Tregs can either drive or suppress disease pathogenesis. This two-sided role for Tregs and their impact on such a broad spectrum of diseases makes them an important focus of study in immuno-oncology and autoimmunity. Preclinical models of these... Read More