Gerald W. Bothe, PhD
Download the presentation slides
Knowledge of the genetic background is crucial for the interpretation of experiments involving animals.
For example, a transgene can be lethal in one mouse line, but not lethal in another line.
The tools for the analysis of the genetic background of mice have improved significantly over the last few years and now include a variety of SNP panels.
This webinar described how to use them in a situation such as importation of a line, backcrossing, and routine maintenance of a line.
More about Gerald W. Bothe, PhD
Post-doctoral fellowship at New York University, where he developed gene-targeted, Cre-recombinase expressing mouse lines.
Worked at Lexicon Genetics in the field of gene targeting.