Black 6 (B6NTac) Related Publications


Chen RZ, Huang RR, Shen CP, MacNeil DJ, Fong TM. (2004) Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice. Brain Res. 999(2):227-30.

Christensen MH, Ishibashi M, Nielsen ML, Leonard CS, Kohlmeier KA. (2014) Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction. Neuropharmacology. 85:263-83.

Heinla I, Leidmaa E, Visnapuu T, Philips MA, Vasar E. (2014) Enrichment and individual housing reinforce the differences in aggressiveness and amphetamine response in 129S6/SvEv and C57BL/6 strains. Behav Brain Res. 267:66-73.

Lim JP, Zou ME, Janak PH, Messing RO. (2012) Responses to ethanol in C57BL/6 versus C57BL/6 × 129 hybrid mice. Brain Behav. 2(1):22-31.

Mangubat M, Lutfy K, Lee ML, Pulido L, Stout D, Davis R, Shin CS, Shahbazian M, Seasholtz S, Sinha-Hikim A, Sinha-Hikim I, O'Dell LE, Lyzlov A, Liu Y, Friedman TC. (2012) Effect of nicotine on body composition in mice. J Endocrinol. 212(3):317-26.

Ren X, Lutfy K, Mangubat M, Ferrini MG, Lee ML, Liu Y, Friedman TC. (2013) Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake. J Obes. 2013:764742.


Bothe GW, Bolivar VJ, Vedder MJ, Geistfeld JG. (2005) Behavioral differences among fourteen inbred mouse strains commonly used as disease models. Comp Med. 55(4):326-34.

Bourdi M, Davies JS, Pohl LR. (2011) Mispairing C57BL/6 substrains of genetically engineered mice and wild-type controls can lead to confounding results as it did in studies of JNK2 in acetaminophen and concanavalin A liver injury. Chem Res Toxicol. 24(6):794-6.

Bryant CD, Zhang NN, Sokoloff G, Fanselow MS, Ennes HS, Palmer AA, McRoberts JA. (2008) Behavioral differences among C57BL/6 substrains: implications for transgenic and knockout studies. J Neurogenet. 22(4):315-31.

Malá H, Chen Y, Worm VH, Kure J, Kaae BH, Madsen U, Badolo L, Pickering DS, Mogensen J. (2012) Cognitive enhancing effects of an AMPA receptor positive modulator on place learning in mice. Behav Brain Res. 226(1):18-25.

Sturm M, Becker A, Schroeder A, Bilkei-Gorzo A, Zimmer A. (2015) Effect of chronic corticosterone application on depression-like behavior in C57BL/6N and C57BL/6J mice. Genes Brain Behav. 14(3):292-300.


Hayes CL, Natividad JM, Jury J, Martin R, Langella P, Verdu EF. (2014) Efficacy of Bifidobacterium breve NCC2950 against DSS-induced colitis is dependent on bacterial preparation and timing of administration. Benef Microbes. 5(1):79-88.

Matsuo S, Yang WL, Aziz M, Kameoka S, Wang P. (2014) Fatty acid synthase inhibitor C75 ameliorates experimental colitis. Mol Med. 20:1-9.

Experimental Autoimmune Encephalomyelitis (EAE)

Isaksson M, Lundgren BA, Ahlgren KM, Kämpe O, Lobell A. (2012) Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE. Eur J Immunol. 42(10):2555-63.

Mony JT, Khorooshi R, Owens T. (2014) Chemokine receptor expression by inflammatory T cells in EAE. Front Cell Neurosci. 8:187.

Mony JT, Khorooshi R, Owens T. (2014) MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE. Mult Scler. 20(10):1312-21.

Tsiftsoglou SA, Sim RB. (2004) Human complement factor I does not require cofactors for cleavage of synthetic substrates. J Immunol. 173(1):367-75.


Billaud M, Lohman AW, Straub AC, Parpaite T, Johnstone SR, Isakson BE. (2012) Characterization of the thoracodorsal artery: morphology and reactivity. Microcirculation. 19(4):360-72.

Boutin SR, Shen Z, Roesch PL, Stiefel SM, Sanderson AE, Multari HM, Pridhoko EA, Smith JC, Taylor NS, Lohmiller JJ, Dewhirst FE, Klein HJ, Fox JG. (2010) Helicobacter pullorum outbreak in C57BL/6NTac and C3H/HeNTac barrier-maintained mice. J Clin Microbiol. 48(5):1908-10.

Chen H, Wu S, Lu R, Zhang YG, Zheng Y, Sun J. (2014) Pulmonary permeability assessed by fluorescent-labeled dextran instilled intranasally into mice with LPS-induced acute lung injury. PLoS One. 9(7):e101925.

Christy AC, Byrnes KR, Settle TL. (2014) Evaluation of medicated gel as a supplement to providing acetaminophen in the drinking water of C57BL/6 mice after surgery. J Am Assoc Lab Anim Sci.53(2):180-4.

Ecoiffier T, Yuen D, Chen L. (2010) Differential distribution of blood and lymphatic vessels in the murine cornea. Invest Ophthalmol Vis Sci. 51(5):2436-40.

Egan CM, Sridhar S, Wigler M, Hall IM. (2007) Recurrent DNA copy number variation in the laboratory mouse. Nat Genet. 39(11):1384-9.

Feng B, Kiyatkin ME, La JH, Ge P, Solinga R, Silos-Santiago I, Gebhart GF. (2013) Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents. J Neurosci. 33(23):9831-9.

Feng B, La JH, Schwartz ES, Tanaka T, McMurray TP, Gebhart GF. (2012) Long-term sensitization of mechanosensitive and -insensitive afferents in mice with persistent colorectal hypersensitivity. Am J Physiol Gastrointest Liver Physiol. 302(7):G676-83.

Feng B, La JH, Tanaka T, Schwartz ES, McMurray TP, Gebhart GF. (2012) Altered colorectal afferent function associated with TNBS-induced visceral hypersensitivity in mice. Am J Physiol Gastrointest Liver Physiol. 303(7):G817-24.

Ferrari G, Hajrasouliha AR, Sadrai Z, Ueno H, Chauhan SK, Dana R. (2013) Nerves and neovessels inhibit each other in the cornea. Invest Ophthalmol Vis Sci. 54(1):813-20.

Forman MB, Gillespie DG, Cheng D, Jackson EK. (2014) A novel adenosine precursor 2',3'-cyclic adenosine monophosphate inhibits formation of post-surgical adhesions. Dig Dis Sci. 59(9):2118-25.

Hajrasouliha AR, Funaki T, Sadrai Z, Hattori T, Chauhan SK, Dana R. (2012) Vascular endothelial growth factor-C promotes alloimmunity by amplifying antigen-presenting cell maturation and lymphangiogenesis. Invest Ophthalmol Vis Sci. 53(3):1244-50.

Hajrasouliha AR, Sadrai Z, Lee HK, Chauhan SK, Dana R. (2013) Expression of the chemokine decoy receptor D6 mediates dendritic cell function and promotes corneal allograft rejection. Mol Vis. 19:2517-25.

Heiker JT, Klöting N, Kovacs P, Kuettner EB, Sträter N, Schultz S, Kern M, Stumvoll M, Blüher M, Beck-Sickinger AG. (2013) Vaspin inhibits kallikrein 7 by serpin mechanism. Cell Mol Life Sci. 70(14):2569-83.

Holschneider DP, Wang Z, Pang RD. (2014) Functional connectivity-based parcellation and connectome of cortical midline structures in the mouse: a perfusion autoradiography study. Front Neuroinform. 8:61.

Huang TT, Naeemuddin M, Elchuri S, Yamaguchi M, Kozy HM, Carlson EJ, Epstein CJ. (2006) Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Hum Mol Genet. 15(7):1187-94.

Ivannikov MV, Sugimori M, Llinás RR. (2013) Synaptic vesicle exocytosis in hippocampal synaptosomes correlates directly with total mitochondrial volume. J Mol Neurosci. 49(1):223-30.

Kaczocha M, Rebecchi MJ, Ralph BP, Teng YH, Berger WT, Galbavy W, Elmes MW, Glaser ST, Wang L, Rizzo RC, Deutsch DG, Ojima I. (2014) Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. PLoS One. 9(4):e94200.

Kalash R, Berhane H, Goff J, Houghton F, Epperly MW, Dixon T, Zhang X, Sprachman MM, Wipf P, Franicola D, Wang H, Greenberger JS. (2013) Effects of thoracic irradiation on pulmonary endothelial compared to alveolar type-II cells in fibrosis-prone C57BL/6NTac mice. In Vivo. 27(3):291-7.

Kalash R, Berhane H, Yang Y, Epperly MW, Wang H, Dixon T, Rhieu B, Greenberger JS, Huq MS.(2014) Improved survival of mice after total body irradiation with 10 MV photon, 2400 MU/min SRS beam. In Vivo. 28(1):1-12.

Kawas LH, McCoy AT, Yamamoto BJ, Wright JW, Harding JW. (2012) Development of angiotensin IV analogs as hepatocyte growth factor/Met modifiers. J Pharmacol Exp Ther. 340(3):539-48.

Kharitonenkov A, Beals JM, Micanovic R, Strifler BA, Rathnachalam R, Wroblewski VJ, Li S, Koester A, Ford AM, Coskun T, Dunbar JD, Cheng CC, Frye CC, Bumol TF, Moller DE.(2013) Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. PLoS One. 8(3):e58575.

Kim H, Bernard ME, Flickinger J, Epperly MW, Wang H, Dixon TM, Shields D, Houghton F, Zhang X, Greenberger JS. (2011) The autophagy-inducing drug carbamazepine is a radiation protector and mitigator. Int J Radiat Biol. 87(10):1052-60.

Købler C, Saber AT, Jacobsen NR, Wallin H, Vogel U, Qvortrup K, Mølhave K. (2014) FIB-SEM imaging of carbon nanotubes in mouse lung tissue. Anal Bioanal Chem. 406(16):3863-73.

Kodandaramaiah SB, Franzesi GT, Chow BY, Boyden ES, Forest CR. (2012) Automated whole-cell patch-clamp electrophysiology of neurons in vivo. Nat Methods. 9(6):585-7.

Kohman RE, Han X, Bleier BS. (2014) Heterotopic mucosal engrafting procedure for direct drug delivery to the brain in mice. J Vis Exp. (89).

Krahe TE, Seabrook TA, Chen CK, Fox MA, Guido W. (2012) Modulation of CREB in the dorsal lateral geniculate nucleus of dark-reared mice. Neural Plast. 2012:426437.

Lan H, Lin HV, Wang CF, Wright MJ, Xu S, Kang L, Juhl K, Hedrick JA, Kowalski TJ. (2012) Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways. Br J Pharmacol. 165(8):2799-807.

Lebsack TW, Fa V, Woods CC, Gruener R, Manziello AM, Pecaut MJ, Gridley DS, Stodieck LS, Ferguson VL, Deluca D. (2010) Microarray analysis of spaceflown murine thymus tissue reveals changes in gene expression regulating stress and glucocorticoid receptors. J Cell Biochem. 110(2):372-81.

Lee HC, Wondimu A, Liu Y, Ma JS, Radoja S, Ladisch S. (2012) Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis. J Immunol. 189(7):3521-7.

Lee SN, Peng B, Desjardins R, Pintar JE, Day R, Lindberg I. (2007) Strain-specific steroidal control of pituitary function. J Endocrinol. 192(3):515-25.

Leib DA, Machalek MA, Williams BR, Silverman RH, Virgin HW. (2000) Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene. Proc Natl Acad Sci USA. 97(11):6097-101.

Lin SA, Patel M, Suresch D, Connolly B, Bao B, Groves K, Rajopadhye M, Peterson JD, Klimas M, Sur C, Bednar B. (2012) Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and α(v)β(3) Integrin. Int J Mol Imaging. 2012:189254.

Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R. (2004) Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc Natl Acad Sci USA. 101(26):9534-9.

Liu G, Li Z, Wei Y, Lin Y, Yang C, Liu T. (2014) Direct detection of FoxP3 expression in thymic double-negative CD4-CD8- cells by flow cytometry. Sci Rep. 4:5781.

Liverani E, Rico MC, Garcia AE, Kilpatrick LE, Kunapuli SP. (2013) Prasugrel metabolites inhibit neutrophil functions. J Pharmacol Exp Ther. 344(1):231-43.

Lloyd SA, Bandstra ER, Willey JS, Riffle SE, Tirado-Lee L, Nelson GA, Pecaut MJ, Bateman TA. (2012) Effect of proton irradiation followed by hindlimb unloading on bone in mature mice: a model of long-duration spaceflight. Bone. 51(4):756-64.

McBrearty BA1, Clark LD, Zhang XM, Blankenhorn EP, Heber-Katz E. (1998) Genetic analysis of a mammalian wound-healing trait. Proc Natl Acad Sci USA. 95(20):11792-7.

McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE. (2014) Alpha-1 acid glycoprotein reduces hepatic leukocyte recruitment in murine models of either early endotoxemia or early sepsis. Microcirculation. 21(1):74-83.

McKinney BC, Schneider JS, Schafer GL, Lowing JL, Mohan S, Zhao MX, Heng MY, Albin RL, Seasholtz AF, Akil H, Murphy GG. (2008) Decreased locomotor activity in mice expressing tTA under control of the CaMKII alpha promoter. Genes Brain Behav. 7(2):203-13.

McLaren DG, Cardasis HL, Stout SJ, Wang SP, Mendoza V, Castro-Perez JM, Miller PL, Murphy BA, Cumiskey AM, Cleary MA, Johns DG, Previs SF, Roddy TP. (2013) Use of [13C18] oleic acid and mass isotopomer distribution analysis to study synthesis of plasma triglycerides in vivo: analytical and experimental considerations. Anal Chem. 85(13):6287-94.

Mennes E, Dungan CM, Frendo-Cumbo S, Williamson DL, Wright DC. (2013) Aging-associated reductions in lipolytic and mitochondrial proteins in mouse adipose tissue are not rescued by metformin treatment. J Gerontol A Biol Sci Med Sci. 69(9):1060-8.

Muise ES, Souza S, Chi A, Tan Y, Zhao X, Liu F, Dallas-Yang Q, Wu M, Sarr T, Zhu L, Guo H, Li Z, Li W, Hu W, Jiang G, Paweletz CP, Hendrickson RC, Thompson JR, Mu J, Berger JP, Mehmet H. (2013) Downstream signaling pathways in mouse adipose tissues following acute in vivo administration of fibroblast growth factor 21. PLoS One. 8(9):e73011.

Muise ES, Zhu Y, Verras A, Karanam BV, Gorski J, Weingarth D, Lin HV, Hwa J, Thompson JR, Hu G, Liu J, He S, DeVita RJ, Shen DM, Pinto S. (2014) Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors. PLoS One. 9(2):e88908.

Nguyen D, Samson SL, Reddy VT, Gonzalez EV, Sekhar RV. (2013) Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione. Aging Cell. 12(3):415-25.

Nyman LR, Cox KB, Hoppel CL, Kerner J, Barnoski BL, Hamm DA, Tian L, Schoeb TR, Wood PA. (2005) Homozygous carnitine palmitoyltransferase 1a (liver isoform) deficiency is lethal in the mouse. Mol Genet Metab. 86(1-2):179-87.

Platt KM, Charnigo RJ, Kincer JF, Dickens BJ, Pearson KJ. (2013) Controlled exercise is a safe pregnancy intervention in mice. J Am Assoc Lab Anim Sci. 52(5):524-30.

Poor SH, Qiu Y, Fassbender ES, Shen S, Woolfenden A, Delpero A, Kim Y, Buchanan N, Gebuhr TC, Hanks SM, Meredith EL, Jaffee BD, Dryja TP. (2014) Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation. Invest Ophthalmol Vis Sci. 55(10):6525-34.

Radetsky LC, Rea MS, Bierman A, Figueiro MG. (2013) Circadian Disruption: comparing humans with mice. Chronobiol Int. 30(8):1066-71.

Rodríguez-Piñeiro AM, Bergström JH, Ermund A, Gustafsson JK, Schütte A, Johansson ME, Hansson GC. (2013) Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins. Am J Physiol Gastrointest Liver Physiol. 305(5):G348-56.

Ryder E, Doe B, Gleeson D, Houghton R, Dalvi P, Grau E, Habib B, Miklejewska E, Newman S, Sethi D, Sinclair C, Vyas S, Wardle-Jones H; Sanger Mouse Genetics Project, Bottomley J, Bussell J, Galli A, Salisbury J, Ramirez-Solis R.(2014) Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase. Transgenic Res. 23(1):177-85.

Sanderson AE, Multari HM, Lohmiller JJ, Boutin SR. (2010) Effect of cage-change frequency on rodent breeding performance. Lab Anim (NY). 39(6):177-82.

Soni C, Wong EB, Domeier PP, Khan TN, Satoh T, Akira S, Rahman ZS. (2014) B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers. J Immunol. 193(9):4400-14.

Tranberg B, Hansen AK, Lykkesfeldt J. (2014) High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice. Eur J Nutr. 53(6):1441-4.

Turk ML, Cacioppo LD, Ge Z, Shen Z, Whary MT, Parry N, Boutin SR, Klein HJ, Fox JG. (2012) Persistent Helicobacter pullorum colonization in C57BL/6NTac mice: a new mouse model for an emerging zoonosis. J Med Microbiol. 61(Pt 5):720-8.

Matsuo S, Yang WL, Aziz M, Jacob A, Wang P. (2013) Cyclic arginine-glycine-aspartate attenuates acute lung injury in mice after intestinal ischemia/reperfusion. Crit Care. 17(1):R19.

Gridley DS, Slater JM, Luo-Owen X, Rizvi A, Chapes SK, Stodieck LS, Ferguson VL, Pecaut MJ. (2009) Spaceflight effects on T lymphocyte distribution, function and gene expression. J Appl Physiol (1985). 106(1):194-202.

Zurita E, Chagoyen M, Cantero M, Alonso R, González-Neira A, López-Jiménez A, López-Moreno JA, Landel CP, Benítez J, Pazos F, Montoliu L. (2010) Genetic polymorphisms among C57BL/6 mouse inbred strains. Transgenic Res. 20(3):481-9.

Anosova NG, Illigens B, Boisgérault F, Fedoseyeva EV, Young MJ, Benichou G. (2001) Antigenicity and immunogenicity of allogeneic retinal transplants. J Clin Invest. 108(8):1175-83.

Cunnusamy K, Niederkorn JY. (2013) IFN-γ blocks CD4+CD25+ Tregs and abolishes immune privilege of minor histocompatibility mismatched corneal allografts. Am J Transplant. 13(12):3076-84.

Hattori T, Saban DR, Emami-Naeini P, Chauhan SK, Funaki T, Ueno H, Dana R. (2012) Donor-derived, tolerogenic dendritic cells suppress immune rejection in the indirect allosensitization-dominant setting of corneal transplantation. J Leukoc Biol. 91(4):621-7.


Schnabolk G, Stauffer K, O'Quinn E, Coughlin B, Kunchithapautham K, Rohrer B. (2014) A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization. Exp Eye Res. 129:18-23.

Simon MM, Greenaway S, White JK, Fuchs H, Gailus-Durner V, Wells S, et al. (2013) A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol. 14(7):R82.

Almodovar AJ, Luther RJ, Stonebrook CL, Wood PA. (2013) Genomic structure and genetic drift in C57BL/6 congenic metabolic mutant mice. Mol Genet Metab. 110(3):396-400.

Bothe GW, Bolivar VJ, Vedder MJ, Geistfeld JG. (2004) Genetic and behavioral differences among five inbred mouse strains commonly used in the production of transgenic and knockout mice. Genes Brain Behav. 3(3):149-57.

Jiu-Zhen Jin and Jixiang Ding. (2015) Strain-Dependent Gene Expression during Mouse Embryonic Palate Development. J Dev Biol. 3(1), 2-10 doi:10.3390/jdb3010002.

Mattapallil MJ, Wawrousek EF, Chan CC, Zhao H, Roychoudhury J, Ferguson TA, Caspi RR. (2012) The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes. Invest Ophthalmol Vis Sci. 53(6):2921-7.

Mekada K, Abe K, Murakami A, Nakamura S, Nakata H, Moriwaki K, Obata Y, Yoshiki A. (2009) Genetic differences among C57BL/6 substrains. Exp Anim. 58(2):141-9.


Baqai FP, Gridley DS, Slater JM, Luo-Owen X, Stodieck LS, Ferguson V, Chapes SK, Pecaut MJ. (2009) Effects of spaceflight on innate immune function and antioxidant gene expression. J Appl Physiol (1985). 106(6):1935-42.

Brodfuehrer J, Rankin A, Edmonds J, Keegan S, Andreyeva T, Lawrence-Henderson R, Ozer J, Gao H, Bloom L, Boisvert A, Lam K, Lee J, LaBranche T, Syed J, Miao W, Singh P. (2014) Quantitative analysis of target coverage and germinal center response by a CXCL13 neutralizing antibody in a T-dependent mouse immunization model. Pharm Res. 31(3):635-48.

Erlebacher A, Lukens AK, Glimcher LH. (2002) Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo. Proc Natl Acad Sci U S A. 99(26):16940-5.

Gray PM, Forrest G, Wisniewski T, Porter G, Freed DC, DeMartino JA, Zaller DM, Guo Z, Leone J, Fu TM, Vora KA. (2012) Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities. Cell Immunol. 278(1-2):113-9.

Spindler TJ, Tseng AW, Zhou X, Adams GB. (2014) Adipocytic cells augment the support of primitive hematopoietic cells in vitro but have no effect in the bone marrow niche under homeostatic conditions. Stem Cells Dev. 23(4):434-41.

Delaney JR, Sykulev Y, Eisen HN, Tonegawa S. (1998) Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection. Proc Natl Acad Sci USA. 95(9):5235-40.

Dolina JS, Sung SS, Novobrantseva TI, Nguyen TM, Hahn YS. (2013) Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity. Mol Ther Nucleic Acids. 2:e72.

Geem D, Medina-Contreras O, McBride M, Newberry RD, Koni PA, Denning TL. (2014) Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes. J Immunol. 193(1):431-8.

Gerber DJ, Pereira P, Huang SY, Pelletier C, Tonegawa S. (1996) Expression of alpha v and beta 3 integrin chains on murine lymphocytes. Proc Natl Acad Sci USA. 93(25):14698-703.

Guo Z, Tilburgs T, Wong B, Strominger JL. (2014) Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication. Proc Natl Acad Sci USA. 111(39):14199-204.

Hargadon KM, Forrest OA, Reddy PR. (2012) Suppression of the maturation and activation of the dendritic cell line DC2.4 by melanoma-derived factors. Cell Immunol. 272(2):275-82.

Huang Z, Zhao C, Chen Y, Cowell JA, Wei G, Kultti A, Huang L, Thompson CB, Rosengren S, Frost GI, Shepard HM. (2014) Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation. J Immunol. 192(11):5285-95.

Hudalla GA, Modica JA, Tian YF, Rudra JS, Chong AS, Sun T, Mrksich M, Collier JH. (2013) A self-adjuvanting supramolecular vaccine carrying a folded protein antigen. Adv Healthc Mater. 2(8):1114-9.

Joseph A, Neff K, Richard J, Gao L, Bangari D, Joly M, Culm-Merdek K, Garman R, Williams J, Richards S, Ruzek M. (2012) Transient low-dose methotrexate induces tolerance to murine anti-thymocyte globulin and together they promote long-term allograft survival. J Immunol. 189(2):732-43.

Källberg E, Ivars F, Leanderson T. (2014) Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity. Scand J Immunol. 79(4):237-43.

Källberg E, Stenström M, Liberg D, Ivars F, Leanderson T. (2012) CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden. BMC Immunol. 13:69.

Kim do Y, Hao J, Liu R, Turner G, Shi FD, Rho JM. (2012) Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis. PLoS One. 7(5):e35476.

Kleiveland CR, Hult LT, Spetalen S, Kaldhusdal M, Christofferesen TE, Bengtsson O, Romarheim OH, Jacobsen M, Lea T. (2013) The noncommensal bacterium Methylococcus capsulatus (Bath) ameliorates dextran sulfate (Sodium Salt)-Induced Ulcerative Colitis by influencing mechanisms essential for maintenance of the colonic barrier function. Appl Environ Microbiol. 79(1):48-56.

Liang SC, Moskalenko M, Van Roey M, Jooss K. (2013) Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy. Clin Immunol. 148(2):287-98.

Ma S, Richardson JA, Bitmansour A, Solberg TD, Pidikiti R, Song K, Stojadinovic S, Vitetta ES, Meyer JJ. (2013) Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation. PLoS One. 8(2):e56607.

Nakao S, Zandi S, Faez S, Kohno R, Hafezi-Moghadam A. (2012) Discontinuous LYVE-1 expression in corneal limbal lymphatics: dual function as microvalves and immunological hot spots. FASEB J. 26(2):808-17.

Niederkorn JY, Chen PW, Mellon J, Stevens C, Mayhew E. (2010) Allergic conjunctivitis exacerbates corneal allograft rejection by activating Th1 and th2 alloimmune responses. J Immunol. 184(11):6076-83.

Peine KJ, Guerau-de-Arellano M, Lee P, Kanthamneni N, Severin M, Probst GD, Peng H, Yang Y, Vangundy Z, Papenfuss TL, Lovett-Racke AE, Bachelder EM, Ainslie KM. (2014) Treatment of experimental autoimmune encephalomyelitis by codelivery of disease associated Peptide and dexamethasone in acetalated dextran microparticles. Mol Pharm. 11(3):828-35.

Reilly EC, Thompson EA, Aspeslagh S, Wands JR, Elewaut D, Brossay L. (2012) Activated iNKT cells promote memory CD8+ T cell differentiation during viral infection. PLoS One. 7(5):e37991.

Santulli-Marotto S, Boakye K, Lacy E, Wu SJ, Luongo J, Kavalkovich K, Coelho A, Hogaboam CM, Ryan M. (2013) Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung. PLoS One. 8(12):e81465.

Schmidt JD, Johansen JD, Nielsen MM, Zimersson E, Svedman C, Bruze M, Engkilde K, Poulsen SS, Geisler C, Bonefeld CM. (2014) Immune responses to hair dyes containing toluene-2,5-diamine. Br J Dermatol. 170(2):352-9.

Shand JC, Qin H, Nasholm N, Capitini CM, Fry TJ. (2014) Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells. Biol Blood Marrow Transplant. 20(1):26-36.

Simard AR, Gan Y, St-Pierre S, Kousari A, Patel V, Whiteaker P, Morley BJ, Lukas RJ, Shi FD (2013) Differential modulation of EAE by α9*- and β2*-nicotinic acetylcholine receptors. Immunol Cell Biol. 91(3):195-200.

Tang Z, Yin JX, Han P, Gan Y, Coons SW, Wang C, Maalouf M, Shi J. (2013) Pertussis toxin attenuates experimental autoimmune encephalomyelitis by upregulating neuronal vascular endothelial growth factor. Neuroreport. 24(9):469-75.

Voynova EN, Skinner J, Bolland S. (2015) Expansion of an atypical NK cell subset in mouse models of systemic lupus erythematosus. J Immunol. 194(4):1503-13.

Yewdall AW, Drutman SB, Jinwala F, Bahjat KS, Bhardwaj N. (2010) CD8+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells. PLoS One. 5(6):e11144.

Yin JX, Tang Z, Gan Y, Li L, Shi F, Coons S, Shi J. (2014) Pertussis toxin modulates microglia and T cell profile to protect experimental autoimmune encephalomyelitis. Neuropharmacology. 18:1-5.

Zhao CB, Coons SW, Cui M, Shi FD, Vollmer TL, Ma CY, Kuniyoshi SM, Shi J. (2014) A new EAE model of brain demyelination induced by intracerebroventricular pertussis toxin. Biochem Biophys Res Commun. 370(1):16-21.

Infectious Disease

Puchta A, Verschoor CP, Thurn T, Bowdish DM. (2014) Characterization of inflammatory responses during intranasal colonization with Streptococcus pneumoniae. J Vis Exp. (83):e50490.

Chen W, Bennink JR, Morton PA, Yewdell JW. (2002) Mice deficient in perforin, CD4+ T cells, or CD28-mediated signaling maintain the typical immunodominance hierarchies of CD8+ T-cell responses to influenza virus. J Virol. 76(20):10332-7.

Flach CF, Mozer M, Sundquist M, Holmgren J, Raghavan S. (2012) Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice. Vaccine. 30(9):1636-43.

Hempel C, Hoyer N, Kildemoes A, Jendresen CB, Kurtzhals JA. (2014) Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 5:291.

Hempel C, Hyttel P, Kurtzhals JA. (2014) Endothelial glycocalyx on brain endothelial cells is lost in experimental cerebral malaria. J Cereb Blood Flow Metab. 34(7):1107-10.

Hempel C, Hyttel P, Staalsø T, Nyengaard JR, Kurtzhals JA. (2012) Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria. Malar J. 11:216.

Igietseme JU, Ukwade C, Ouburg S, Omosun Y, Joseph K. (2015) Profile of Anti-Chlamydia Immune Responses in Complicated (Infertile) and Non-complicated (Fertile) Genital Infections. J Clin Immunol Immunother. 2: 006.

Ihrig M, Whary MT, Dangler CA, Fox JG. (2005) Gastric helicobacter infection induces a Th2 phenotype but does not elevate serum cholesterol in mice lacking inducible nitric oxide synthase. Infect Immun. 73(3):1664-70.

Langlois RA, Albrecht RA, Kimble B, Sutton T, Shapiro JS, Finch C, Angel M, Chua MA, Gonzalez-Reiche AS, Xu K, Perez D, García-Sastre A, tenOever BR. (2013) MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies. Nat Biotechnol. 31(9):844-7.

Navabi N, Johansson ME, Raghavan S, Lindén SK. (2013) Helicobacter pylori infection impairs the mucin production rate and turnover in the murine gastric mucosa. Infect Immun. 81(3):829-37.

Pak-Wittel MA, Yang L, Sojka DK, Rivenbark JG, Yokoyama WM. (2013) Interferon-γ mediates chemokine-dependent recruitment of natural killer cells during viral infection. Proc Natl Acad Sci USA. 110(1):E50-9.

Robinson KM, McHugh KJ, Mandalapu S, Clay ME, Lee B, Scheller EV, Enelow RI, Chan YR, Kolls JK, Alcorn JF. (2013) Influenza A virus exacerbates Staphylococcus aureus pneumonia in mice by attenuating antimicrobial peptide production. J Infect Dis. 209(6):865-75.

Metabolic and Cardiovascular

Almind K, Kahn CR. (2004) Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes. 53(12):3274-85.

Bay P, Rowlandson S, Kraft J, Peshavaria M, Jetton T. (2014) Plant-Derived Bioactive Lipids Impacts Glucose Homeostasis and Energy Metabolism in Mice. UVM Honors College Senior Theses. Paper 36.

Bianchi E, Carrington PE, Ingallinella P, Finotto M, Santoprete A, Petrov A, Eiermann G, Kosinski J, Marsh DJ, Pocai A, SinhaRoy R, Pessi A. (2013) A PEGylated analog of the gut hormone oxyntomodulin with long-lasting antihyperglycemic, insulinotropic and anorexigenic activity. Bioorg Med Chem. 21(22):7064-73.

Billaud M, Johnstone SR, Isakson BE. (2012) Loss of compliance in small arteries, but not in conduit arteries, after 6 weeks exposure to high fat diet. J Cardiovasc Transl Res. 5(3):256-63.

Campbell SC, Wisniewski PJ, Noji M, McGuinness LR, Häggblom MM, Lightfoot SA, Joseph LB, Kerkhof LJ. (2016) The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice. PLoS One. 11(3):e0150502.

Chen Z, Wang SP, Krsmanovic ML, Castro-Perez J, Gagen K, Mendoza V, Rosa R, Shah V, He T, Stout SJ, Geoghagen NS, Lee SH, McLaren DG, Wang L, Roddy TP, Plump AS, Hubbard BK, Sinz CJ, Johns DG. (2012) Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters. Metabolism. 61(4):470-81.

Clements ME, Chaber CJ, Ledbetter SR, Zuk A. (2013) Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury. PLoS One. 8(8):e70464.

Clemmensen C, Madsen AN, Smajilovic S, Holst B, Bräuner-Osborne H. (2012) L-Arginine improves multiple physiological parameters in mice exposed to diet-induced metabolic disturbances. Amino Acids. 43(3):1265-75.

Deshpande D, Kethireddy S, Gattacceca F, Amiji M. (2014) Comparative pharmacokinetics and tissue distribution analysis of systemically administered 17-β-estradiol and its metabolites in vivo delivered using a cationic nanoemulsion or a peptide-modified nanoemulsion system for targeting atherosclerosis. J Control Release. 180:117-24.

Franzén S, Friederich-Persson M, Fasching A, Hansell P, Nangaku M, Palm F. (2014) Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 306(10):F1171-8.

Freeman HC, Hugill A, Dear NT, Ashcroft FM, Cox RD. (2006) Deletion of nicotinamide nucleotide transhydrogenase: a new quantitive trait locus accounting for glucose intolerance in C57BL/6J mice. Diabetes. 55(7):2153-6.

Freeman H, Cox RD. (2006) Type-2 diabetes: a cocktail of genetic discovery. Hum Mol Genet. 15 Spec No 2:R202-9.

Friedman TC, Sinha-Hikim I, Parveen M, Najjar SM, Liu Y, Mangubat M, Shin CS, Lyzlov A, Ivey R, Shaheen M, French SW, Sinha-Hikim AP (2012) Additive effects of nicotine and high-fat diet on hepatic steatosis in male mice. Endocrinology. 153(12):5809-20.

Garcia-Menendez L, Karamanlidis G, Kolwicz S, Tian R. (2013) Substrain specific response to cardiac pressure overload in C57BL/6 mice. Am J Physiol Heart Circ Physiol. 305(3):H397-402.

Gareski T, Will S, Kubasiak D, Unger TJ, Li X, Panza D, Qadri A, Bedard P, Ranganath S, Gimeno R, Hahm S, Perreault M. (2009) The Severity of Insulin Resistance in C57BL/6 Mice Depends on Genetic Background and Dietary Fat Source. Wyeth, Cambridge, MA. American Diabetes Association 2009 Abstract Number: 1713-P

Giller K, Huebbe P, Hennig S, Dose J, Pallauf K, Doering F, Rimbach G. (2013) Beneficial effects of a 6-month dietary restriction are time-dependently abolished within 2 weeks or 6 months of refeeding-genome-wide transcriptome analysis in mouse liver. Free Radic Biol Med. 61:170-8.

Heiker JT, Kunath A, Kosacka J, Flehmig G, Knigge A, Kern M, Stumvoll M, Kovacs P, Blüher M, Klöting N. (2014) Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains. Physiol Genomics. 46(11):377-84.

Kahle M, Horsch M, Fridrich B, Seelig A, Schultheiß J, Leonhardt J, Irmler M, Beckers J, Rathkolb B, Wolf E, Franke N, Gailus-Durner V, Fuchs H, de Angelis MH, Neschen S. (2013) Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis. Mol Metab. 2(4):435-46.

Kalliokoski O, Jacobsen KR, Teilmann AC, Hau J, Abelson KS. (2012) Quantitative effects of diet on fecal corticosterone metabolites in two strains of laboratory mice. In Vivo. 26(2):213-21.

Kern M, Knigge A, Heiker JT, Kosacka J, Stumvoll M, Kovacs P, Blüher M, Klöting N. (2012) C57BL/6JRj mice are protected against diet induced obesity (DIO). Biochem Biophys Res Commun. 417(2):717-20.

Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, Kumar R, Grinberg AV, Liharska K, Ucran JA, Howard E, Spiegelman BM, Seehra J, Lachey J. (2012) A novel therapeutic approach to treating obesity through modulation of TGFβ signaling. Endocrinology. 153(7):3133-46.

Kucharczyk J, Nestoridi E, Kvas S, Andrews R, Stylopoulos N (2013) Probing the mechanisms of the metabolic effects of weight loss surgery in humans using a novel mouse model system. J Surg Res. 179(1):e91-8.

Lankas GR, Leiting B, Roy RS, Eiermann GJ, Beconi MG, Biftu T, Chan CC, Edmondson S, Feeney WP, He H, Ippolito DE, Kim D, Lyons KA, Ok HO, Patel RA, Petrov AN, Pryor KA, Qian X, Reigle L, Woods A, Wu JK, Zaller D, Zhang X, Zhu L, Weber AE, Thornberry NA. (2005) Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9. Diabetes. 54(10):2988-94.

Lillefosse HH, Clausen MR, Yde CC, Ditlev DB, Zhang X, Du ZY, Bertram HC, Madsen L, Kristiansen K, Liaset B. (2014) Urinary loss of tricarboxylic acid cycle intermediates as revealed by metabolomics studies: an underlying mechanism to reduce lipid accretion by whey protein ingestion? J Proteome Res. 13(5):2560-70.

Mori MA, Liu M, Bezy O, Almind K, Shapiro H, Kasif S, Kahn CR. (2010) A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease. Diabetes. 59(11):2960-71.

Nestoridi E, Kvas S, Kucharczyk J, Stylopoulos N. (2012) Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice. Endocrinology. 153(5):2234-44.

Podrini C, Cambridge EL, Lelliott CJ, Carragher DM, Estabel J, Gerdin AK, Karp NA, Scudamore CL; Sanger Mouse Genetics Project, Ramirez-Solis R, White JK. (2013) High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice. Mamm Genome. 24(5-6):240-51.

Rajpal DK, Klein JL, Mayhew D, Boucheron J, Spivak AT, Kumar V, Ingraham K, Paulik M, Chen L, Van Horn S, Thomas E, Sathe G, Livi GP, Holmes DJ, Brown JR. (2015) Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models. PLoS One. 10(12):e0145499.

Rinnankoski-Tuikka R, Hulmi JJ, Torvinen S, Silvennoinen M, Lehti M, Kivelä R, Reunanen H, Kujala UM, Kainulainen H. (2014) Lipid droplet-associated proteins in high-fat fed mice with the effects of voluntary running and diet change. Metabolism. 63(8):1031-40.

Rune I, Hansen CH, Ellekilde M, Nielsen DS, Skovgaard K, Rolin BC, Lykkesfeldt J, Josefsen K, Tranberg B, Kihl P, Hansen AK. (2013) Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent. J Diabetes Res. 2013:319321.

Walker A, Pfitzner B, Neschen S, Kahle M, Harir M, Lucio M, Moritz F, Tziotis D, Witting M, Rothballer M, Engel M, Schmid M, Endesfelder D, Klingenspor M, Rattei T, Castell WZ, de Angelis MH, Hartmann A, Schmitt-Kopplin P. (2014) Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet. ISME J. 8(12):2380-96.

Wen S, Jadhav KS, Williamson DL, Rideout TC. (2013) Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice. J Lipids. 2013:908048.


Campbell SC, Wisniewski PJ, Noji M, McGuinness LR, Häggblom MM, Lightfoot SA, Joseph LB, Kerkhof LJ. (2016) The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice. PLoS One. 11(3):e0150502.

Celaj S, Gleeson MW, Deng J, O'Toole GA, Hampton TH, Toft MF, Morrison HG, Sogin ML, Putra J, Suriawinata AA, Gorham JD. (2014) The microbiota regulates susceptibility to Fas-mediated acute hepatic injury. Lab Invest. 94(9):938-49.

Harley IT, Giles DA, Pfluger PT, Burgess SL, Walters S, Hembree J, Raver C, Rewerts CL, Downey J, Flick LM, Stankiewicz TE, McAlees JW, Wills-Karp M, Balfour Sartor R, Divanovic S, Tschöp MH, Karp CL. (2013) Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice. Mol Metab. 2(3):171-83.

Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, Wei D, Goldfarb KC, Santee CA, Lynch SV, Tanoue T, Imaoka A, Itoh K, Takeda K, Umesaki Y, Honda K, Littman DR. (2009) Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 139(3):485-98.

Ivanov II, Frutos Rde L, Manel N, Yoshinaga K, Rifkin DB, Sartor RB, Finlay BB, Littman DR. (2008) Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe. 4(4):337-49.

Kasahara DI, Mathews JA, Brand JD, Shore SA, Cho Y. (2014) The Effects Of A Depleted Gut Microbiome On Ozone Induced Airway Hyperresponsiveness And Inflammation In Mice. Am J Respir Crit Care Med. 189:A6390.

Lee SM, Donaldson GP, Mikulski Z, Boyajian S, Ley K, Mazmanian SK. (2013) Bacterial colonization factors control specificity and stability of the gut microbiota. Nature. 501(7467):426-9.

Longman RS, Yang Y, Diehl GE, Kim SV, Littman DR. (2013) Microbiota: host interactions in mucosal homeostasis and systemic autoimmunity. Cold Spring Harb Symp Quant Biol. 78:193-201.

Park AJ, Collins J, Blennerhassett PA, Ghia JE, Verdu EF, Bercik P, Collins SM. (2013) Altered colonic function and microbiota profile in a mouse model of chronic depression. Neurogastroenterol Motil. 25(9):733-e575.

Peloquin JM, Nguyen DD. (2013) The microbiota and inflammatory bowel disease: insights from animal models. Anaerobe. 24:102-6.

Pragman AA, Kim HB, Reilly CS, Wendt C, Isaacson RE. (2012) The lung microbiome in moderate and severe chronic obstructive pulmonary disease. PLoS One. 7(10):e47305.

Rajpal DK, Klein JL, Mayhew D, Boucheron J, Spivak AT, Kumar V, Ingraham K, Paulik M, Chen L, Van Horn S, Thomas E, Sathe G, Livi GP, Holmes DJ, Brown JR. (2015) Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models. PLoS One. 10(12):e0145499.

Rolig AS, Cech C, Ahler E, Carter JE, Ottemann KM. (2013) The degree of Helicobacter pylori-triggered inflammation is manipulated by preinfection host microbiota. Infect Immun. 81(5):1382-9.

Schott B, Martin RA, Ather JL, Poynter ME. (2014) Segmented Filamentous Bacteria Colonization Does Not Alter Responses to Allergic Airway Sensitization and Challenge. Annals of the American Thoracic Society. 1 (2014):78-79.

Sivan A, Corrales L, and Gajewski T. (2014) Evidence implicating the commensal microbiota in shaping anti-tumor immunity in melanoma. J Immunother Cancer. 2(Suppl 3):O11.

Yang Y, Torchinsky MB, Gobert M, Xiong H, Xu M, Linehan JL, Alonzo F, Ng C, Chen A, Lin X, Sczesnak A, Liao JJ, Torres VJ, Jenkins MK, Lafaille JJ, Littman DR. (2014) Focused specificity of intestinal TH17 cells towards commensal bacterial antigens. Nature. 510(7503):152-6.

Zvanych R, Lukenda N, Kim JJ, Li X, Petrof EO, Khan WI, Magarvey NA. (2014) Small molecule immunomodulins from cultures of the human microbiome member Lactobacillus plantarum. J Antibiot (Tokyo). 67(1):85-8.

Model Creation

Kirchain SM, Hayward AM, Mkandawire JM, Qi P, Burds AA. (2008) Comparison of tetraploid blastocyst microinjection of outbred Crl:CD1(ICR), hybrid B6D2F1/Tac, and inbred C57BL/6NTac embryos for generation of mice derived from embryonic stem cells. Comp Med. 58(2):145-50.

Liu L, Nutter LM, Law N, McKerlie C. (2009) Sperm freezing and in vitro fertilization in three substrains of C57BL/6 mice. J Am Assoc Lab Anim Sci. 48(1):39-43.


Nomura Y, Fujii F, Sato C, Nemoto M, Tamura M. (2000) Exchange transfusion with fluorocarbon for studying synaptically evoked optical signal in rat cortex. Brain Res Brain Res Protoc. 5(1):10-5.

Bailey RM, Howard J, Knight J, Sahara N, Dickson DW, Lewis J. (2014) Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model. Mol Neurodegener. 9:8.

Chandran P, Upadhyay J, Markosyan S, Lisowski A, Buck W, Chin CL, Fox G, Luo F, Day M. (2012) Magnetic resonance imaging and histological evidence for the blockade of cuprizone-induced demyelination in C57BL/6 mice. Neuroscience. 202:446-53.

Devi L, Ohno M. (2013) Effects of levetiracetam, an antiepileptic drug, on memory impairments associated with aging and Alzheimer's disease in mice. Neurobiol Learn Mem. 102:7-11.

Heyward FD, Walton RG, Carle MS, Coleman MA, Garvey WT, Sweatt JD. (2012) Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression. Neurobiol Learn Mem. 98(1):25-32.

Lin Z, Dodd CA, Filipov NM. (2013) Short-term atrazine exposure causes behavioral deficits and disrupts monoaminergic systems in male C57BL/6 mice. Neurotoxicol Teratol. 39:26-35.

Loane DJ, Stoica BA, Tchantchou F, Kumar A, Barrett JP, Akintola T, Xue F, Conn PJ, Faden AI. (2014) Novel mGluR5 positive allosteric modulator improves functional recovery, attenuates neurodegeneration, and alters microglial polarization after experimental traumatic brain injury. Neurotherapeutics. 11(4):857-69

Moore SJ, Deshpande K, Stinnett GS, Seasholtz AF, Murphy GG. (2013) Conversion of short-term to long-term memory in the novel object recognition paradigm. Neurobiol Learn Mem. 105:174-85.

Parameshwaran K, Irwin MH, Steliou K, Pinkert CA. (2012) Protection by an antioxidant of rotenone-induced neuromotor decline, reactive oxygen species generation and cellular stress in mouse brain. Pharmacol Biochem Behav. 101(3):487-92.

Peters M, Bletsch M, Stanley J, Wheeler D, Scott R, Tully T. (2014) The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. Neuropsychopharmacology. 39(13):2938-48.

Russo I, Caracciolo L, Tweedie D, Choi SH, Greig NH, Barlati S, Bosetti F. (2012) 3,6'-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit. J Neurochem. 122(6):1181-92.

Schizas N, Andersson B, Hilborn J, Hailer NP. (2014) Interleukin-1 receptor antagonist promotes survival of ventral horn neurons and suppresses microglial activation in mouse spinal cord slice cultures. J Neurosci Res. 92(11):1457-65.


Gao Y, Whitaker-Dowling P, Barmada MA, Basse PH, Bergman I. (2014) Viral infection of implanted meningeal tumors induces antitumor memory T-cells to travel to the brain and eliminate established tumors. Neuro Oncol. 17(4):536-44.

Huijbers EJ, Femel J, Andersson K, Björkelund H, Hellman L, Olsson AK. (2012) The non-toxic and biodegradable adjuvant Montanide ISA 720/CpG can replace Freund's in a cancer vaccine targeting ED-B--a prerequisite for clinical development. Vaccine. 30(2):225-30.

Jiang ZK, Johnson M, Moughon DL, Kuo J, Sato M, Wu L. (2013) Rapamycin enhances adenovirus-mediated cancer imaging and therapy in pre-immunized murine hosts. PLoS One. 8(9):e73650.

Liang X, De Vera ME, Buchser WJ, Romo de Vivar Chavez A, Loughran P, Beer Stolz D, Basse P, Wang T, Van Houten B, Zeh HJ 3rd, Lotze MT. (2012) Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression. Cancer Res. 72(11):2791-801.

Nilsson LM, Forshell TZ, Rimpi S, Kreutzer C, Pretsch W, Bornkamm GW, Nilsson JA. (2012) Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis. PLoS Genet. 8(3):e1002573.

Qu X, Felder MA, Perez Horta Z, Sondel PM, Rakhmilevich AL. (2013) Antitumor effects of anti-CD40/CpG immunotherapy combined with gemcitabine or 5-fluorouracil chemotherapy in the B16 melanoma model. Int Immunopharmacol. 17(4):1141-7.

Rakowski LA, Garagiola DD, Li CM, Decker M, Caruso S, Jones M, Kuick R, Cierpicki T, Maillard I, Chiang MY. (2013) Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias. Cancer Res. 73(2):930-41.

Schürch C, Riether C, Amrein MA, Ochsenbein AF. (2013) Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ. J Exp Med. 210(3):605-21.

Sevko AL, Barysik N, Perez L, Shurin MR, Gerein V. (2007) Differences in dendritic cell activation and distribution after intravenous, intraperitoneal, and subcutaneous injection of lymphoma cells in mice. Adv Exp Med Biol. 601:257-64.

Wentworth L, Meyers JV, Alam S, Russ AJ, Suresh M, Cho CS. (2013) Memory T cells are uniquely resistant to melanoma-induced suppression. Cancer Immunol Immunother. 62(1):149-59.


Garciafigueroa DY, Klei LR, Ambrosio F, Barchowsky A. (2013) Arsenic-stimulated lipolysis and adipose remodeling is mediated by G-protein-coupled receptors. Toxicol Sci. 134(2):335-44.

National Toxicology Program. (2012) Toxicology study of senna (CAS No. 8013-11-4) in C57BL/6NTAC Mice and toxicology and carcinogenesis study of senna in genetically modified C3B6.129F1/Tac-Trp53tm1Brd haploinsufficient mice (Feed Studies). Natl Toxicol Program Genet Modif Model Rep. (15):1-114.

Husain M, Saber AT, Guo C, Jacobsen NR, Jensen KA, Yauk CL, Williams A, Vogel U, Wallin H, Halappanavar S. (2013) Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation. Toxicol Appl Pharmacol. 269(3):250-62.

Lin Z, Dodd CA, Xiao S, Krishna S, Ye X, Filipov NM. (2014) Gestational and lactational exposure to atrazine via the drinking water causes specific behavioral deficits and selectively alters monoaminergic systems in C57BL/6 mouse dams, juvenile and adult offspring. Toxicol Sci. 141(1):90-102.

Moirangthem V, Katz WS, Su W, Choi EY, Dingle RW, Zeigler GM, Everson WV, Jennings CD, Gong M, Swanson HI. (2013) Impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cutaneous wound healing. Exp Toxicol Pathol. 65(1-2):61-7.