About the webinar:
Diet-induced mouse models are important tools for metabolic disease research, and experimental outcomes can be greatly affected by housing and husbandry elements. This is true whether you’re purchasing preconditioned mice or conditioning them in-house. To ensure your experiments run successfully, it’s important to manage factors such as acclimation time, enrichment, cage density and diet.
Mice that are fed a high fat diet for prolonged periods can develop aggression and suffer from adverse outcomes such as fight wounds and alopecia. In this webinar, we focus on models of obesity and NASH that are induced by exposure to a high-fat diet. We’ll use the Taconic Diet Induced Obese B6 and Diet Induced NASH B6 as key examples. This webinar empowers you with the critical information you need to plan and successfully execute studies using DIO and NASH mice.
Watch this webinar to learn about:
- Acclimation, housing and husbandry recommendations for use with Taconic DIO B6 and Diet Induced NASH B6 models
- How diet selection affects high fat diet-induced metabolic disease models
- The impact of transit on obese mouse models and how to ensure proper acclimation time
- The impact of sex, strain, substrain, and thermoneutral housing on high fat diet-induced metabolic disease models
- How to successfully maintain animals for prolonged periods and reduce adverse outcomes
- How to account for biological variability
