Humanized PXR-CAR Mouse Publications

Humanized PXR-CAR Mouse Model Page

Filter publications by application: All Oncology
Filter publications by model type: All



Paper Title


Model Type


Full Text

Braeuning A, et al.
Mouse over for full list
Braeuning A, Gavrilov A, Brown S, Wolf CR, Henderson CJ, Schwarz M
(2014) Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR. Toxicol. Sci. 140(2):259-70
Scheer N, et al.
Mouse over for full list
Scheer N, Ross J, Rode A, Zevnik B, Niehaves S, Faust N, Wolf CR
(2008) A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. J. Clin. Invest. 118(9):3228-39
Scheer N, et al.
Mouse over for full list
Scheer N, Ross J, Kapelyukh Y, Rode A, Wolf CR
(2010) In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice. Drug Metab. Dispos. 38(7):1046-53
Ross J, et al.
Mouse over for full list
Ross J, Plummer SM, Rode A, Scheer N, Bower CC, Vogel O, Henderson CJ, Wolf CR, Elcombe CR
(2010) Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo. Toxicol. Sci. 116(2):452-66

Welcome! Tell us a little about yourself