HLA-A2.1 Publications

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Kotturi MF, et al.
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Kotturi MF, Botten J, Sidney J, Bui HH, Giancola L, Maybeno M, Babin J, Oseroff C, Pasquetto V, Greenbaum JA, Peters B, Ting J, Do D, Vang L, Alexander J, Grey H, Buchmeier MJ, Sette A
(2009) A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease. PLoS Pathog. 5(12):e1000695
Infectious Disease, Vaccine Research
Tan AC, et al.
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Tan AC, La Gruta NL, Zeng W, Jackson DC
(2011) Precursor frequency and competition dictate the HLA-A2-restricted CD8+ T cell responses to influenza A infection and vaccination in HLA-A2.1 transgenic mice. J. Immunol. 187(4):1895-902
Infectious Disease, Vaccine Research
Singh RA, et al.
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Singh RA, Barry MA
(2003) Generation of multivalent genome-wide T cell responses in HLA-A*0201 transgenic mice by an HIV-1 expression library immunization (ELI) vaccine. Res Initiat Treat Action 8(2):17-9
Infectious Disease, HIV, Vaccine Research
Singh RA, et al.
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Singh RA, Wu L, Barry MA
(2002) Generation of genome-wide CD8 T cell responses in HLA-A*0201 transgenic mice by an HIV-1 ubiquitin expression library immunization vaccine. J. Immunol. 168(1):379-91
Infectious Disease, HIV, Vaccine Research
Pasquetto V, et al.
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Pasquetto V, Bui HH, Giannino R, Banh C, Mirza F, Sidney J, Oseroff C, Tscharke DC, Irvine K, Bennink JR, Peters B, Southwood S, Cerundolo V, Grey H, Yewdell JW, Sette A
(2005) HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products. J. Immunol. 175(8):5504-15
Infectious Disease
Nanjundappa RH, et al.
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Nanjundappa RH, Wang R, Xie Y, Umeshappa CS, Xiang J
(2012) Novel CD8+ T cell-based vaccine stimulates Gp120-specific CTL responses leading to therapeutic and long-term immunity in transgenic HLA-A2 mice. Vaccine 30(24):3519-25
Vaccine Research
Kang YJ, et al.
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Kang YJ, Zeng W, Song W, Reinhold B, Choi J, Brusic V, Yamashita T, Munshi A, Li C, Minvielle S, Anderson KC, Munshi N, Reinherz EL, Sasada T
(2013) Identification of human leucocyte antigen (HLA)-A*0201-restricted cytotoxic T lymphocyte epitopes derived from HLA-DOβ as a novel target for multiple myeloma. Br. J. Haematol. 163(3):343-51
Oncology, Myeloma, Vaccine Research
Casnici C, et al.
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Casnici C, Volpe G, Crotta K, Lattuada D, Saglio G, Marelli O
(2012) Immunologic evaluation of peptides derived from BCR/ABL-out-of-frame fusion protein in HLA A2.1 transgenic mice. J. Immunother. 35(4):321-8
Oncology, Vaccine Research
Botten J, et al.
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Botten J, Alexander J, Pasquetto V, Sidney J, Barrowman P, Ting J, Peters B, Southwood S, Stewart B, Rodriguez-Carreno MP, Mothe B, Whitton JL, Sette A, Buchmeier MJ
(2006) Identification of protective Lassa virus epitopes that are restricted by HLA-A2. J. Virol. 80(17):8351-61
Infectious Disease, Vaccine Research
Yoshida M, et al.
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Yoshida M, Ishioka Y, Ozawa T, Okuyama H, Iguchi M, Ota T, Ito T, Nagira M, Morita A, Tanaka H, Naito H, Kidoya H, Takakura N
(2017) Soluble HLA-associated peptide from PSF1 has a cancer vaccine potency. Sci Rep 7(1):11137
Vaccine Research
Testa JS, et al.
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Testa JS, Shetty V, Hafner J, Nickens Z, Kamal S, Sinnathamby G, Philip R
(2012) MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response. PLoS ONE 7(11):e48484
Infectious Disease, Vaccine Research
Zhai MX, et al.
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Zhai MX, Chen F, Zhao YY, Wu YH, Li GD, Gao YF, Qi YM
(2015) Novel epitopes identified from efflux pumps of Mycobacterium tuberculosis could induce cytotoxic T lymphocyte response. PeerJ 3:e1229
Infectious Disease, Tuberculosis
Weiskopf D, et al.
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Weiskopf D, Yauch LE, Angelo MA, John DV, Greenbaum JA, Sidney J, Kolla RV, De Silva AD, de Silva AM, Grey H, Peters B, Shresta S, Sette A
(2011) Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design. J. Immunol. 187(8):4268-79
Infectious Disease, Dengue, Vaccine Research
Wilson CC, et al.
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Wilson CC, McKinney D, Anders M, MaWhinney S, Forster J, Crimi C, Southwood S, Sette A, Chesnut R, Newman MJ, Livingston BD
(2003) Development of a DNA vaccine designed to induce cytotoxic T lymphocyte responses to multiple conserved epitopes in HIV-1. J. Immunol. 171(10):5611-23
Infectious Disease, HIV, Vaccine Research
Vitiello A, et al.
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Vitiello A, Marchesini D, Furze J, Sherman LA, Chesnut RW
(1991) Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex. J. Exp. Med. 173(4):1007-15
Infectious Disease
Tseng-Rogenski SS, et al.
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Tseng-Rogenski SS, Arredouani MS, Escara-Wilke JF, Neeley YC, Imperiale MJ, Sanda MG
(2009) A safety-modified SV40 Tag developed for human cancer immunotherapy. Drug Des Devel Ther 2:17-24
Oncology, Vaccine Research, Immuno-Oncology
Seavey MM, et al.
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Seavey MM, Pan ZK, Maciag PC, Wallecha A, Rivera S, Paterson Y, Shahabi V
(2009) A novel human Her-2/neu chimeric molecule expressed by Listeria monocytogenes can elicit potent HLA-A2 restricted CD8-positive T cell responses and impact the growth and spread of Her-2/neu-positive breast tumors. Clin. Cancer Res. 15(3):924-32
Oncology, Immuno-Oncology
Oseroff C, et al.
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Oseroff C, Sette A, Wentworth P, Celis E, Maewal A, Dahlberg C, Fikes J, Kubo RT, Chesnut RW, Grey HM, Alexander J
(1998) Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses. Vaccine 16(8):823-33
Infectious Disease, Hepatitis-B, Hepatitis-C, Vaccine Research
McKinney DM, et al.
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McKinney DM, Skvoretz R, Livingston BD, Wilson CC, Anders M, Chesnut RW, Sette A, Essex M, Novitsky V, Newman MJ
(2004) Recognition of variant HIV-1 epitopes from diverse viral subtypes by vaccine-induced CTL. J. Immunol. 173(3):1941-50
HIV, Vaccine Research
Men Y, et al.
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Men Y, Miconnet I, Valmori D, Rimoldi D, Cerottini JC, Romero P
(1999) Assessment of immunogenicity of human Melan-A peptide analogues in HLA-A*0201/Kb transgenic mice. J. Immunol. 162(6):3566-73
Vaccine Research
Dubey JP, et al.
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Dubey JP, Ferreira LR, Martins J, McLeod R
(2012) Oral oocyst-induced mouse model of toxoplasmosis: effect of infection with Toxoplasma gondii strains of different genotypes, dose, and mouse strains (transgenic, out-bred, in-bred) on pathogenesis and mortality. Parasitology 139(1):1-13
Infectious Disease
Depla E, et al.
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Depla E, Van der Aa A, Livingston BD, Crimi C, Allosery K, De Brabandere V, Krakover J, Murthy S, Huang M, Power S, Babé L, Dahlberg C, McKinney D, Sette A, Southwood S, Philip R, Newman MJ, Meheus L
(2008) Rational design of a multiepitope vaccine encoding T-lymphocyte epitopes for treatment of chronic hepatitis B virus infections. J. Virol. 82(1):435-50
Hepatitis-B, Vaccine Research
Cong H, et al.
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Cong H, Mui EJ, Witola WH, Sidney J, Alexander J, Sette A, Maewal A, McLeod R
(2011) Towards an immunosense vaccine to prevent toxoplasmosis: protective Toxoplasma gondii epitopes restricted by HLA-A*0201. Vaccine 29(4):754-62
Infectious Disease, Vaccine Research
Botten J, et al.
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Botten J, Whitton JL, Barrowman P, Sidney J, Whitmire JK, Alexander J, Kotturi MF, Sette A, Buchmeier MJ
(2010) A multivalent vaccination strategy for the prevention of Old World arenavirus infection in humans. J. Virol. 84(19):9947-56
Infectious Disease, Vaccine Research
Botten J, et al.
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Botten J, Whitton JL, Barrowman P, Sidney J, Whitmire JK, Alexander J, Ting JP, Bui HH, Sette A, Buchmeier MJ
(2007) HLA-A2-restricted protection against lethal lymphocytic choriomeningitis. J. Virol. 81(5):2307-17
Infectious Disease, Vaccine Research
Alexander J, et al.
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Alexander J, Oseroff C, Dahlberg C, Qin M, Ishioka G, Beebe M, Fikes J, Newman M, Chesnut RW, Morton PA, Fok K, Appella E, Sette A
(2002) A decaepitope polypeptide primes for multiple CD8+ IFN-gamma and Th lymphocyte responses: evaluation of multiepitope polypeptides as a mode for vaccine delivery. J. Immunol. 168(12):6189-98
Vaccine Research