Cyp2f2 Knockout Mouse Publications

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Cruzan G, et al.
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Cruzan G, Bus J, Hotchkiss J, Harkema J, Banton M, Sarang S
(2012) CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors. Regul. Toxicol. Pharmacol. 62(1):214-20
Lung Cancer
Carlson GP
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Carlson GP
(2012) Modification of the metabolism and toxicity of styrene and styrene oxide in hepatic cytochrome P450 reductase deficient mice and CYP2F2 deficient mice. Toxicology 294(2-3):104-8
Li L, et al.
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Li L, Wei Y, Van Winkle L, Zhang QY, Zhou X, Hu J, Xie F, Kluetzman K, Ding X
(2011) Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa. J. Pharmacol. Exp. Ther. 339(1):62-71