APPSWE - Model 2789 Publications

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Faraco G, et al.
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Faraco G, Hochrainer K, Segarra SG, Schaeffer S, Santisteban MM, Menon A, Jiang H, Holtzman DM, Anrather J, Iadecola C
(2019) Dietary salt promotes cognitive impairment through tau phosphorylation. Nature 574(7780):686-690
Jensen MM, et al.
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Jensen MM, Arvaniti M, Mikkelsen JD, Michalski D, Pinborg LH, Härtig W, Thomsen MS
(2015) Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease. Neurobiol Aging 36(4):1629-1638
Hartz AMS, et al.
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Hartz AMS, Zhong Y, Shen AN, Abner EL, Bauer B
(2018) Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer's Disease Mouse Model. Front Aging Neurosci 10:186
Ding Y, et al.
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Ding Y, Zhong Y, Baldeshwiler A, Abner EL, Bauer B, Hartz AMS
(2021) Protecting P-glycoprotein at the blood-brain barrier from degradation in an Alzheimer's disease mouse model. Fluids Barriers CNS 18(1):10
Akkaya BG, et al.
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Akkaya BG, Zolnerciks JK, Ritchie TK, Bauer B, Hartz AM, Sullivan JA, Linton KJ
(2015) The multidrug resistance pump ABCB1 is a substrate for the ubiquitin ligase NEDD4-1. Mol Membr Biol 32(2):39-45
Mandler M, et al.
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Mandler M, Santic R, Gruber P, Cinar Y, Pichler D, Funke SA, Willbold D, Schneeberger A, Schmidt W, Mattner F
(2015) Tailoring the antibody response to aggregated Aß using novel Alzheimer-vaccines. PLoS One 10(1):e0115237
Shirey JK, et al.
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Shirey JK, Brady AE, Jones PJ, Davis AA, Bridges TM, Kennedy JP, Jadhav SB, Menon UN, Xiang Z, Watson ML, Christian EP, Doherty JJ, Quirk MC, Snyder DH, Lah JJ, Levey AI, Nicolle MM, Lindsley CW, Conn PJ
(2009) A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning. J Neurosci 29(45):14271-86
Hoe HS, et al.
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Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW
(2009) Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. J Neurosci 29(23):7459-73
Laursen B, et al.
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Laursen B, Mørk A, Plath N, Kristiansen U, Bastlund JF
(2014) Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration. Brain Res 1543:253-62
Hartz AM, et al.
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Hartz AM, Bauer B, Soldner EL, Wolf A, Boy S, Backhaus R, Mihaljevic I, Bogdahn U, Klünemann HH, Schuierer G, Schlachetzki F
(2012) Amyloid-β contributes to blood-brain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy. Stroke 43(2):514-23
Lee KJ, et al.
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Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS
(2010) Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience 169(1):344-56
Ohta H, et al.
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Ohta H, Arai S, Akita K, Ohta T, Fukuda S
(2012) Effects of NK-4 in a transgenic mouse model of Alzheimer's disease. PLoS One 7(1):e30007
Landlinger C, et al.
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Landlinger C, Oberleitner L, Gruber P, Noiges B, Yatsyk K, Santic R, Mandler M, Staffler G
(2015) Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer's disease. J Neuroinflammation 12:150
Dong YF, et al.
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Dong YF, Kataoka K, Tokutomi Y, Nako H, Nakamura T, Toyama K, Sueta D, Koibuchi N, Yamamoto E, Ogawa H, Kim-Mitsuyama S
(2011) Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease. FASEB J 25(9):2911-20
Wong LR, et al.
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Wong LR, Wong P, Ho PC
(2020) Metabolic Profiling of Female Tg2576 Mouse Brains Provides Novel Evidence Supporting Intranasal Low-Dose Pioglitazone for Long-Term Treatment at an Early Stage of Alzheimer's Disease. Biomedicines 8(12)
Rustay NR, et al.
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Rustay NR, Cronin EA, Curzon P, Markosyan S, Bitner RS, Ellis TA, Waring JF, Decker MW, Rueter LE, Browman KE
(2010) Mice expressing the Swedish APP mutation on a 129 genetic background demonstrate consistent behavioral deficits and pathological markers of Alzheimer's disease. Brain Res. 1311:136-47
Wolf A, et al.
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Wolf A, Bauer B, Abner EL, Ashkenazy-Frolinger T, Hartz AM
(2016) A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice. PLoS ONE 11(1):e0147733
Neuroscience
Goncalves MB, et al.
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Goncalves MB, Clarke E, Hobbs C, Malmqvist T, Deacon R, Jack J, Corcoran JP
(2013) Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist. Eur. J. Neurosci. 37(7):1182-92
Neuroscience, Alzheimer's
Hsiao K, et al.
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Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G
(1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274(5284):99-102
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