Author(s) |
(Date) |
Paper Title |
Citation |
Model Type |
Applications |
Full Text |
| Margeta MA, et al. Mouse over for full list |
(2022) | Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma. | Immunity | |||
| Miranda AM, et al. Mouse over for full list |
(2022) | Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice. | Transl Psychiatry 12(1):129 | |||
| Keeney JT, et al. Mouse over for full list |
(2015) | Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention. | J Alzheimers Dis 48(2):411-24 | Gene replacement |
Cardiovascular, Metabolism, Alzheimer's | |
| Wu L, et al. Mouse over for full list |
(2018) | Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention. | J. Neurosci. | |||
| Jo DH, et al. Mouse over for full list |
(2015) | Gene expression profiles of primary retinal pigment epithelial cells from apolipoprotein E knockout and human apolipoprotein E2 transgenic mice. | Genet. Mol. Res. 14(1):1855-67 | Knock out, Knock in |
Metabolism | |
| Tagalakis AD, et al. Mouse over for full list |
(2001) | Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty. | J. Biol. Chem. 276(16):13226-30 | Knock in |
Metabolism, Neuroscience, Alzheimer's | |
| Malek G, et al. Mouse over for full list |
(2005) | Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration. | Proc. Natl. Acad. Sci. U.S.A. 102(33):11900-5 | |||
| Knouff C, et al. Mouse over for full list |
(1999) | Apo E structure determines VLDL clearance and atherosclerosis risk in mice. | J. Clin. Invest. 103(11):1579-86 | |||
| Gerritsen G, et al. Mouse over for full list |
(2003) | Hyperlipidemia in APOE2 transgenic mice is ameliorated by a truncated apoE variant lacking the C-terminal domain. | J. Lipid Res. 44(2):408-14 | |||
| Sullivan PM, et al. Mouse over for full list |
(1998) | Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. | J. Clin. Invest. 102(1):130-5 |
Welcome! Tell us a little about yourself