Pdgfrb-Cre Mouse

Random Transgenic

Pdgfrb-Cre Random Transgenic Mouse Model
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CALL: 888.822.6642 + 45 70 23 04 05 (EUROPE)
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • 13075-F
    B6.129-Tg(Pdgfrb-cre)9Rha
  • 13075-M
    B6.129-Tg(Pdgfrb-cre)9Rha

  • Tissue specific cre deleter
  • Expresses cre recombinase under the control of the Pdgfrb promoter
  • Permits cre recombination in pericytes and smooth vascular muscle cells
  • May be useful for angiogenesis studies

Origin:

The Pdgfrb-Cre Mouse was developed in the laboratory of Ralf Adams at the London Research Institute. The model was generated by microinjecting a transgene containing a genomic Pdgfrb promoter fragment fused to cre recombinase and a polyA sequence, into 129/B6 zygotes. Founder lines were maintained on a mixed 129;B6 background. Taconic received embryos from CRT in 2013.

Source:

Sponsor: Cancer Research Technology

Availability:

This model is available for immediate cryorecovery. 

Species:

Mouse

Initial Publication:

Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH. (2006) Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 124(1):161-73.

Access to this model requires execution of a Limited Breeding Agreement and cryorecovery services to recover the line. Current Limited Breeding Agreement fees for this model are $3,000/€2550 per year for non-profit users and $10,000/€8500 per year for for-profit users. Cryorecovery fees are additional.