Taconic Biosciences News

Taconic Biosciences News is your source for current and relevant news on how animal models are being used to drive drug discovery. Use the links below to explore exciting announcements from Taconic via Press Releases, Taconic’s press coverage in Publications and Media, and critical scientific insights within Industry News.

Gene Therapy: A New Twist on an Old Helix

Genetic Engineering & Biotechnology news interviews Taconic's Dr. Adriano Flora on how "model providers can create a model of human disease to test the efficacy of the gene therapy in vivo": "What do you do when you have a chronic or even crippling disease that you happened to get just because you inherited it? As little as three decades ago, you would have been stuck with the...

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BACE inhibition-dependent repair of Alzheimer's pathophysiology

This PNAS article demonstrates "that BACE inhibition is beneficial to all levels of impairment in an AD mouse model": "Amyloid-β (Aβ) is thought to play an essential pathogenic role in Alzheimer´s disease (AD). A key enzyme involved in the generation of Aβ is the β-secretase BACE, for which powerful inhibitors have been developed and are currently in use in human clinical trials. However, although BACE inhibition can...

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BeHEARD: 2016/2017 Competition Results

Taconic Biosciences is recognized as a participating company in the Rare Genomics Institute's BeHeard Competition: Teresa Luperchio, from Johns Hopkins University, will receive animal model design services from Taconic focused on Kabuki Syndrome See all of the contest winners and updates at: RareGenomics.org...

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Pulling Back the Pre-Clinical Curtain

The Translational Scientist converses with Taconic's Portfolio Director Dr. John Couse about pre-clinical mouse models, specifically "how the shifting techniques and technologies in bioscience affect — and are affected by — mouse models": "The pre-clinical mouse model is an essential part of many translational medicine journeys, providing preliminary efficacy results that often determine if treatments are able to make the leap into clinical trials. With the growing...

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Mice in microgravity: how rodent research in space accelerates study timelines

Outsourcing-Pharma features Taconic's Dr. Gretchen Kusek who discusses Taconic mice bred specifically for a mission to the International Space Station: "Forty mice were launched into space last week aboard the SpaceX Dragon, which will deliver the genetically engineered research models to the International Space Station for study in microgravity. The mission — "Rodent Research-5" — is the result of a collaboration between the University of California, Los...

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Mice in Space: Taconic Mice Included on Launch to International Space Station

Hudson, NY — June 1, 2017 - When the SpaceX Dragon spacecraft launches today bound for the International Space Station, they will be joined by 40 special mice, bred specifically for this mission by Taconic Biosciences, a global leader in genetically engineered mouse models and associated services. The project is a collaboration between the University of California, Los Angeles (UCLA), the Center for the Advancement of Science...

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Athletes' Microbiomes Differ from Nonathletes

The Scientist explores the relationship between the microbiome and athleticism: "Genomicist Lauren Petersen has been racing mountain bikes since she was 14 years old. But throughout her teens she battled chronic Lyme disease, suffering recurring bouts of illness that sometimes kept her off her wheels. "I'd feel like crap for a month or two, and then the antibiotics would make me feel like crap, and then I'd...

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Taconic Biosciences Secures CRISPR License from ERS Genomics

Hudson, NY — May 30, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it has signed a license agreement with ERS Genomics ("ERS") to utilize the company's CRISPR-Cas9 technology to generate unique murine models. Under the agreement, Taconic receives a worldwide non-exclusive license to the CRISPR-Cas9 patents often referred to as the "UC Berkeley patent." ERS Genomics founder, Emmanuelle...

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Genetic drift: the ghost in the genome

Lab Animal quotes Dr. Ana Perez with regards to a process that vendors perform, after there have been a number of generations of rodent research models, to delay genetic drift: "Spontaneous mutations can lead scientists down the wrong path, but awareness in academia and new measures by industry are helping to keep genetic drift at bay. Harvard immunologist Shiv Pillai was puzzled. His team was studying how...

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Pharmatest Launches Novel Humanised Mouse Model of Tumor Growth in Bone

Taconic is featured in this press release from Pharmatest Services,Ltd., as both have collaborated "to develop a novel humanised mouse model of tumor growth in bone that can be used for testing immunotherapies": "Testing compound efficacy in bone microenvironment should substantially decrease the very high number of cancer drugs currently failing in clinical trials due to poor efficacy. Pharmatest Services is a contract research organisation that offers...

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