Taconic Biosciences News

Taconic Biosciences News is your source for current and relevant news on how animal models are being used to drive drug discovery. Use the links below to explore exciting announcements from Taconic via Press Releases, Taconic’s press coverage in Publications and Media, and critical scientific insights within Industry News.

Something old, something new... a marriage of technologies for Immuno-oncology In Vivo studies

Dr. Philip Dubé is the author of this Drug Discovery World article due to his expertise with animal models and immuno-oncology research: "Discovering & validating novel therapeutic targets to add to the immuno-oncology arsenal requires refined preclinical models that meet needs for suitability, scalability & clinical relevancy throughout the phases of target discovery & drug validation. The use of animal models in oncology has undergone a revolution...

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Oriental Medicine Samhwangsasim-tang Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Th1 Cell Responses and Upregulating Treg Cell Responses

Frontiers in Pharmacology examines Oriental medicine Samhwangsasim-tang (SHSST) and — by employing mice sourced from Taconic's Cambridge City, IN location — assesses the value SHSST may have regarding the treatment of chronic inflammatory diseases such as multiple sclerosis (MS): "In this study, we investigated whether SHSST has a beneficial effect in treating myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (EAE). Onset-treatment with SHSST was found to alleviate neurological...

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Predict Drug Toxicity without Guesswork

Dr. Michael Seiler discusses Taconic's rasH2 model and how selecting the correct model will allow for faster study duration and accuracy: "The road from a drug's conception in the laboratory to its arrival in the pharmacy is long and arduous. It can also take over 12 years and cost over $350 million before a drug finds a place on pharmacy shelves. The initial laboratory testing itself is...

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Why A Central Square Stool Bank Is Paying $40 Per Poop Donation

WGBH News discusses fecal transplants and how this relatively new medical procedure is being used to treat Clostridium difficile or C. diff: "A new storefront is opening steps from Cambridge City Hall. But instead of trying to sell you something, its mission is to buy something you produce: your poop. OpenBiome is the world's largest stool bank. It's just like a blood bank but for fecal matter....

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Special Report on Neuroscience: Image-ine that

DDNews spotlights Taconic's Dr. Paul Volden regarding how animal models can provide important insights into neurological disorders: "The leather chair squeaks as the psychiatrist adjusts her position, her legs slowly going numb as she waits for her patient to open up. An hour into their session and the patient has yet to say a word. "I understand that you have been isolating yourself from your family," the...

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Service Providers Aim for Cancer Moonshot at AACR 2017

Science Exchange highlights Taconic as a leader in the development of predictive animal models at AACR 2017: "Greetings from the AACR Annual Meeting! This year, we heard Joe Biden's report on the progress of the Beau Biden Cancer Moonshot Initiative, compared immuno-oncology combination therapies, and mulled over the use of CRISPR screening to finding epigenetically controlled loci. We also checked out the groundbreaking research being done by...

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April Edition: Cancer Research Industry News

Cancer Research Industry News discusses the benefits of using humanized mice with Taconic's Dr. Michael Seiler: "Q: Can you give us an overview of the humanized mice product offering at Taconic? A: The humanized mouse program at Taconic generates three models all based on the super immune deficient CIEA NOG mouse platform. To generate short term models of immune system function, we engraft human PBMC (peripheral blood...

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Choosing CRISPR-based screens in cancer

Nature features critical commentary on CRISPR from Taconic's Dr. John Couse: "Many possibilities for parsing cancer emerge when labs combine gene editing and screens. And RNAi retains its spot in the menu of options." Read* the complete article at: Nature.com *Registration required to view complete article...

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Taconic Biosciences Launches ExpressMODEL™, A New Accelerated Model Generation Service

Hudson, NY — March 31, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, has launched ExpressMODEL™, an innovative and streamlined model generation service that reduces the timeline to first generation and experimental cohort by up to four months. This novel model generation method significantly reduces the time required to create an experimental rodent cohort, enabling critical drug discovery testing to...

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Taconic Announces Sponsorship of 2017 Translational Microbiome Conference

Leading Discussions on Key Animal Model Considerations for Studying the Microbiome Hudson, NY — March 13, 2017 - Taconic Biosciences, the only commercial provider of germ free rodent models, announced that it will sponsor the Translational Microbiome Conference to be held in Boston April 11-13, 2017. This three-day conference will focus on the potential for translational intervention in microbiome research and the challenges associated with successful microbiome...

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