Taconic Biosciences News

Taconic Biosciences News is your source for current and relevant news on how animal models are being used to drive drug discovery. Use the links below to explore exciting announcements from Taconic via Press Releases, Taconic’s press coverage in Publications and Media, and critical scientific insights within Industry News.

Researchers use gene editing to eliminate HIV infection in mice

CBS News reports that for the first time researchers have successfully eliminated the HIV virus from lab mice, by means of CRISPR gene editing technology: "Have researchers taken a step closer to developing an eventual cure for HIV? A Temple University-led team hopes so, by using a gene editing technique to successfully remove HIV infection from lab mice. The gene-editing tool called CRISPR -- which allows scientists...

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More Tooth, More Tail in CRISPR Operations

This Genetic Engineering & Biotechnology news article spotlights Taconic Biosciences' Adriano Flora, PhD, an expert in custom model generation: "The tooth-to-tail ratio, or the balance of frontline troops to support echelons, can determine success or failure in any complicated operation. Originally a military notion, the tooth-to-tail ratio also applies to commercial and scientific endeavors, such as the routinization of genome editing. Ideally, genome-editing technologies such as the...

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Taconic Biosciences Expands Microbiome Product and Service Platform

Hudson, NY — April 26, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services and the only commercial provider of germ-free mice, announced that effective April 26, 2017 they will expand their microbiome product and services platform to include custom Fecal Microbiota Transplantation (FMT) services. To support these new FMT services, Taconic will also offer custom germ-free derivations using either client...

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Taconic Biosciences Announces Release of New Parkinson's Disease Animal Model

Hudson, NY — April 25, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced that effective April 17, 2017, in conjunction with The Michael J. Fox Foundation for Parkinson's Research (MJFF), will begin commercial distribution of a new Parkinson's disease mouse Model 13940 (C57BL/6- Lrrk2tm4.1Arte). The development of Model 13940 underscores the commitment of both Taconic and MJFF to provide...

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Something old, something new... a marriage of technologies for Immuno-oncology In Vivo studies

Dr. Philip Dubé is the author of this Drug Discovery World article due to his expertise with animal models and immuno-oncology research: "Discovering & validating novel therapeutic targets to add to the immuno-oncology arsenal requires refined preclinical models that meet needs for suitability, scalability & clinical relevancy throughout the phases of target discovery & drug validation. The use of animal models in oncology has undergone a revolution...

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Oriental Medicine Samhwangsasim-tang Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Th1 Cell Responses and Upregulating Treg Cell Responses

Frontiers in Pharmacology examines Oriental medicine Samhwangsasim-tang (SHSST) and — by employing mice sourced from Taconic's Cambridge City, IN location — assesses the value SHSST may have regarding the treatment of chronic inflammatory diseases such as multiple sclerosis (MS): "In this study, we investigated whether SHSST has a beneficial effect in treating myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis (EAE). Onset-treatment with SHSST was found to alleviate neurological...

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Predict Drug Toxicity without Guesswork

Dr. Michael Seiler discusses Taconic Biosciences' rasH2 model and how selecting the correct model will allow for faster study duration and accuracy: "The road from a drug's conception in the laboratory to its arrival in the pharmacy is long and arduous. It can also take over 12 years and cost over $350 million before a drug finds a place on pharmacy shelves. The initial laboratory testing itself...

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Why A Central Square Stool Bank Is Paying $40 Per Poop Donation

WGBH News discusses fecal transplants and how this relatively new medical procedure is being used to treat Clostridium difficile or C. diff: "A new storefront is opening steps from Cambridge City Hall. But instead of trying to sell you something, its mission is to buy something you produce: your poop. OpenBiome is the world's largest stool bank. It's just like a blood bank but for fecal matter....

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Special Report on Neuroscience: Image-ine that

DDNews spotlights Taconic Biosciences' Dr. Paul Volden regarding how animal models can provide important insights into neurological disorders: "The leather chair squeaks as the psychiatrist adjusts her position, her legs slowly going numb as she waits for her patient to open up. An hour into their session and the patient has yet to say a word. "I understand that you have been isolating yourself from your family,"...

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Service Providers Aim for Cancer Moonshot at AACR 2017

Science Exchange highlights Taconic Bioscience as a leader in the development of predictive animal models at AACR 2017: "Greetings from the AACR Annual Meeting! This year, we heard Joe Biden's report on the progress of the Beau Biden Cancer Moonshot Initiative, compared immuno-oncology combination therapies, and mulled over the use of CRISPR screening to finding epigenetically controlled loci. We also checked out the groundbreaking research being done...

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