Metabolic Disease INSIGHTS

C57BL/6 DIO 101: Best Practices for Diet Induced Obesity in Mice

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A DIO (diet induced obese) mouse is a C57BL/6 - "Black 6" - mouse which has been made obese through conditioning with a special diet. These diets tend to be high in fat, however there are sometimes other modifications made such as added sugar and there are varying types of fat used to create the diet. Obese Black 6 mice can be used to effectively model pre-diabetic...  Read More