NEW MODEL: Jh mouse on B6 background Learn More

Immunology INSIGHTS

Confused About Ly5, Cd45, and Ptprc?

photo from Confused About Ly5, Cd45, and Ptprc?

Changes in gene names, along with a reversal of allele designation in 1987, have led to much confusion regarding antigen specificity of the Ptprc gene. Ptprc is the gene symbol for the protein tyrosine phosphatase, receptor type C. Komura, et al. (1975), first described a T cell antigen and classified it as Ly5.1 in C57BL/6 mice and Ly5.2 in SJL mice. To follow gene nomenclature, these designations...  Read More