Colony Management Solutions INSIGHTS

Easier Said than Bred: 4 Considerations for Breeding Laboratory Mice

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Have you ever had a mouse infestation in your house? This is a pesky problem that can prove difficult to resolve. After all, they breed like... well, mice. So why is it so difficult to breed laboratory mice? Laboratory mice are purpose-bred for specific phenotypes or traits, not to optimize litter size. Quite often, fecundity is sacrificed to attain traits desired for laboratory mouse studies, or breeding...  Read More

Academic Research - Pool of available GEMs increases by 75 models

photo from Academic Research - Pool of available GEMs increases by 75 models

Taconic Biosciences has recently added an additional 75 mouse models to the GEM Collection Repository. The GEM Collection's nearly 300 lines provide academic and nonprofit researchers worldwide with unparalleled access to a wide range of genetically engineered mouse models. These mouse models are relevant to several disease areas, such as cardiovascular, diabetes/ endocrinology, neuroscience, oncology, respiratory, and immunology. The GEM Collection repository offers nonprofit researchers immediate access...  Read More

Additional Mouse Models Added to the Knockout Repository

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Taconic Biosciences has recently added an additional 19 mouse models to the Knockout Repository (KOR). The KOR's more than 4,100 lines provide academic and commercial researchers worldwide with unparalleled access to fully licensed knockout mouse models. This repository offers the scientific community immediate access to expertly designed, highly valuable research tools that rapidly accelerate translational research and the drug discovery and development processes. Mutations are focused on...  Read More

Taconic Biosciences Product Highlight - The Knockout Mouse Repository (KOR)

photo from Taconic Biosciences Product Highlight - The Knockout Mouse Repository (KOR)

The Taconic Biosciences Knockout Mouse Repository's more than 4,100 lines provide academic and commercial researchers worldwide with unparalleled access to fully licensed knockout mouse models. This repository offers the scientific community immediate access to expertly derived, highly valuable research tools that rapidly accelerate translational research and the drug discovery and development processes. Eliminating the time associated with the design and development of these mouse models provides a...  Read More

Why Would You Want a Black 6 Mouse That Isn't Black?

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Taconic Biosciences introduced two new B6 albino models in late 2012 and early 2013. The B6 Albino A++ (model 11227) and the B6 Albino (model 11971) were generated at Taconic’s Cologne, Germany, site via gene targeting technology. These models represent the first albino B6 models available on the C57BL/6NTac (Taconic B6) background. We all know that the B6 strain is black…so why would you want an albino...  Read More

GEMs Risk Management

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When our computers crash, we immediately panic, wondering if our data will be lost forever. We recall how often our Information Technology department reminds us to back up our data and how often we ignore this suggestion. Now, how about rodent lines? Who reminds us to back up our unique genetically engineered model (GEM) so that the model—the gene of interest, our research funding—isn’t lost forever should...  Read More

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