Media Coverage

The COVID-19 Race: how mouse models will help researchers cross the finish line

The COVID-19 Race: how mouse models will help researchers cross the finish line

Research into COVID-19 is rapidly evolving, and Taconic Biosciences' Dr. Megan MacBride explains in a recent article in Drug Discovery News how mouse models will enable researchers to move forward with SARS-CoV-2 research. She also provides examples of several genetically-engineered mouse models that were previously developed to study SARS, a closely-related coronavirus, may be viable candidates for studying COVID-19 viral infection: "The CRISPR/Cas9 system, and variants of...  Read More

Special Report on Neuroscience: On good behavior

Special Report on Neuroscience: On good behavior

In a recent article published in Drug Discovery News, Taconic's Dr. Terina Martinez explains how behavior is influenced by multiple molecular pathways. She goes on to note that studies that aim to explore behavioral observations must be carefully designed and researchers should be very thoughtful in the interpretation of results. As a first step towards advancing neuroscience studies in humans, researchers should first conduct their studies in...  Read More

Special Report on Liver Disease: The phantom menace

Special Report on Liver Disease: The phantom menace

Non-alcoholic fatty liver disease (NAFLD) is a growing concern for clinicians and researchers, alike. One key problem with understanding how widespread this disease is, as it usually develops slowly and without symptoms. In a recent article for Drug Discovery News (DDN), Taconic's Field Applications Scientist Dr. Janell Richardson described how mouse models are helping advance research in this field. While no one model is perfect for modeling...  Read More

Minding the Microbiome of Your Mice

Minding the Microbiome of Your Mice

The microbiome is increasingly cited as a key regulator of health and disease. This article published in Lab Animal highlights the role of differing microbiomes from different animal model vendors, as well as the importance of maintaining a consistent microbiome to increase reproducibility. As mentioned, Taconic's TruBIOME solution enables researchers to develop a specific microbiota and maintain it for multiple generations of breeding. Read more here...  Read More

Delivering Next-Gen Microbiome Models

Delivering Next-Gen Microbiome Models

Pharma Tech Outlook recently featured Taconic Biosciences as a top microbiome solutions provider in 2020. Dr. Alexander Maue, a Scientific Program Manager at Taconic with extensive experience in immunology and germ-free mice, was featured in this article to comment on evolving research into the microbiome of mouse models. He specifically highlights the growing microbiota repository, which enables researchers to select a specific microbiome for association with their...  Read More

Intellia Therapeutics to Present New Preclinical Data from Its CRISPR/Cas9 Programs at the 23rd Annual Meeting of the American Society of Gene and Cell Therapy

Intellia Therapeutics to Present New Preclinical Data from Its CRISPR/Cas9 Programs at the 23rd Annual Meeting of the American Society of Gene and Cell Therapy

The 23rd Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT) will be taking place virtually from May 12-15, 2020. Intellia Therapeutics Inc., a company specializing in genome editing using CRISPR/Cas9, announced that five poster abstracts have been accepted for presentation at this meeting. One specific poster, titled "In Vivo Model Development for Genome-Edited T Cell Therapeutics", demonstrates the use of improved murine models...  Read More

Betting on the Bug: The Microbiome's Impact on Drug Efficacy

Betting on the Bug: The Microbiome's Impact on Drug Efficacy

Taconic's Dr. Alexander Maue recently authored a follow-up article for International Biopharmaceutical Industry (IBI) to his original comment on how the microbiome can improve reproducibility and translatability of animal models. In part two, he elaborates on how the microbiome can impact drug efficacy and what types of mouse models are being developed to further immuno-oncology research. Read the complete article at: biopharmaceuticalmedia.com...  Read More

Bitten By the Bug - A Flurry of Investments Fuel Microbiome Drug Discovery

Bitten By the Bug - A Flurry of Investments Fuel Microbiome Drug Discovery

Recent research into the microbiome demonstrates that the composition of gut microbiota influences the development and progression of disease. However, more research is needed to fully strengthen this connection. Taconic's Dr. Alexander Maue recently authored an article for Drug Discovery World depicting the investment landscape of biotech and pharmaceutical companies in the microbiome field. Dr. Maue describes how the number of IPOs, mergers & acquisitions, collaborations, and...  Read More

Using Sales, Inventory, and Operations Planning to Support the 3Rs

Using Sales, Inventory, and Operations Planning to Support the 3Rs

SIOP is an important process for many companies, and of prime importance for mouse model generation. Taconic's Terry Receveur was recently featured in AALAS discussing this process, and how it supports the 3Rs of animal research: Replacement, Reduction, and Refinement. The goal of SIOP is to develop a plan for sales, production, inventory, new product development, strategic initiatives, and financials. Read the complete article at: aalas.org...  Read More

Getting Precise: How Humanized Models Aid in Biologics Drug Discovery

Getting Precise: How Humanized Models Aid in Biologics Drug Discovery

In a recent article for Drug Target Review, Taconic's Dr. Paul Volden emphasizes how humanized immune system (HIS) mouse models have enabled the development of numerous immunotherapies. HIS models contain human immune cells and can offer more translatability in drug discovery and development than genetically engineered models. There are now a wide-variety of humanized mice available from animal model vendors, including the severely immunodeficient CIEA NOG mouse...  Read More