Taconic Biosciences News

Taconic Biosciences News is your source for current and relevant news on how animal models are being used to drive drug discovery. Use the links below to explore exciting announcements from Taconic via Press Releases, Taconic’s press coverage in Publications and Media, and critical scientific insights within Industry News.

CRISPR, the Next Generation

Biocompare quotes Taconic Biosciences' Dr. John Couse who details how Easi-CRISPR technology has "brought greater efficiencies, ease, and speed to the generation of a number of model types:" "In just six years, the word CRISPR has gone from meaning a drawer in your refrigerator to the hottest field in biological science. Even people who've never so much as glanced at a copy of Scientific American have probably...

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Taconic Biosciences Launches European Production of Diet Induced Obesity Model

Rensselaer, NY — June 12, 2018 - Taconic Biosciences, a global leader in providing genetically engineered mouse model and service solutions, has launched local production of the Taconic diet induced obesity (DIO) model in Europe. DIO mice are used to study metabolic disease and obesity because they exhibit elevated glucose, insulin, cholesterol, leptin, and corticosterone, thus mimicking many aspects and complications of human metabolic disease. The Diet...

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Special Report on Cancer: Aiming for avatars

Dr. Azusa Tanaka of Taconic Biosciences describes the importance of researchers choosing between orthotopic and heterotopic models, that [in the example of a brain tumor] "researchers need to consider how challenging such microsurgeries would be in terms of both technical expertise and time, particularly when the goal is large drug screens:" "The model host is also a significant factor as researchers look to build their PDX models,...

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Scientist.com and Taconic Biosciences Offer Online Access to Next Generation Easi-CRISPR Technology

Researchers can now access Taconic Easi-CRISPR rodent models on the Scientist.com online marketplace San Diego, CA — May 21, 2018 - Scientist.com, the life science industry's leading online marketplace for outsourced research, announced today that it has partnered with Taconic Biosciences, a global leader in providing genetically engineered rodent model and service solutions. Pharmaceutical and biotech users of the Scientist.com marketplace can now purchase rodent models generated...

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Natural born KILLERS - how natural killer cell therapy will transform immunotherapy

Taconic Biosciences' Dr. Azusa Tanaka and Dr. Michael Seiler penned this Drug Discovery World article regarding NK (natural killer) cell therapy and how this will transform immunotherapy: "Regulatory approval of CAR-T cell therapies in 2017 placed the spotlight on immunotherapy approaches that use live cells to attack tumours - a major shift in oncology treatment. Yet even this groundbreaking therapy has limitations, such as when patients already...

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Taconic Biosciences Licenses Easi-CRISPR Technology from the University of Nebraska

Rensselaer, NY — April 20, 2018 - Taconic Biosciences, a global leader in providing genetically engineered mouse model and service solutions, has been granted a license to the Easi-CRISPR technology from the University of Nebraska. Easi-CRISPR was developed in the laboratories of Drs. Masato Ohtsuka (Tokai University in Japan), and Channabasavaiah Gurumurthy (University of Nebraska). The terms of the agreement include a world-wide, non-exclusive license to the...

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Taconic Biosciences Launches New Inflammatory Bowel Disease Models

Rensselaer, NY — April 19, 2018 - Taconic Biosciences, a global leader in providing genetically engineered mouse model and service solutions, announces the launch of several new inflammatory bowel disease (IBD) animal models. As a fully-licensed provider of CRISPR/Cas9 gene editing technology, Taconic scientists knocked out the mouse Il10 gene to generate a spontaneous colitis mouse models. The new knockout models were created on Taconic's B6 (C57BL/6NTac)...

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GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway

In Scientific Reports volume 8, Article number: 5750(2018), S Kelinsimon et al. from Universitätsmedizin, Berlin, Germany analyzed modulatory effects on the cell cycle by viscumTT in three osteosarcoma cell lines in vivo with eight-week-old female CIEA NOG mouse® (NOD.Cg-Prkdcscid Il2rgtm1Sug/JicTac) from Taconic Biosciences. In several pediatric tumor entities, ViscumTT has shown synergistic induction of apoptosis. In this paper, they report reduction of tumor volume and confirmed the...

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GEN Roundup: Animal Models Primed for Evolutionary Burst

Dr. Michael Seiler of Taconic Biosciences discusses animal models that will advance research, drug testing, and clinical studies in this Genetic Engineering & Biotechnology News article: "Dramatic environmental change imposes new challenges. It also creates new opportunities, opening niches and potentially triggering a period of adaptive radiation, a rapid diversification of new forms. Although adaptive radiation is usually understood to be a process that occurs in nature,...

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The silent microbiome crisis

The Washington Post focuses on the concern of many scientists that "Microbes are disappearing from our bodies," and discusses potential contributing factors: "It is a crisis some scientists believe has similar proportions to climate change, but it gets much less coverage: Microbes are disappearing from our bodies. You may have heard that trillions of microbes -- bacteria, fungi, viruses, protists -- live on every surface of your...

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