Taconic Biosciences News

Hudson, NY — August 8, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it has signed a collaborative agreement with Cergentis B.V. ("Cergentis") to leverage the company's Targeted Locus Amplification (TLA) technology to provide transgene mapping services to its customers. While transgenic mice generated via random pro-nuclear injection (PNI) continue to be a critical tool in biomedical research, a...

Frontiers in Neurology discusses research performed at the University of Florida utilizing Taconic mice: "Janus kinase 3 (JAK3) is associated with the common gamma chain of several interleukin (IL) receptors essential to inflammatory signaling. To study the potential role of JAK3 in stroke-induced neuroinflammation, we subjected mice to permanent middle cerebral artery occlusion and investigated the effects of JAK3 inhibition with decernotinib (VX-509) on infarct size, behavior,...

Researchers hopeful this new model will address incurable and painful disease Hudson, NY — July 5, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it has signed a collaborative agreement with Pharmatest Services, Ltd. ("Pharmatest") to leverage the company's oncology and skeletal disease preclinical efficacy services using Taconic's humanized mouse models. Bone metastasis develops when cancer spreads from elsewhere...

Genetic Engineering & Biotechnology news interviews Taconic's Dr. Adriano Flora on how "model providers can create a model of human disease to test the efficacy of the gene therapy in vivo": "What do you do when you have a chronic or even crippling disease that you happened to get just because you inherited it? As little as three decades ago, you would have been stuck with the...

Taconic Biosciences is recognized as a participating company in the Rare Genomics Institute's BeHeard Competition: Teresa Luperchio, from Johns Hopkins University, will receive animal model design services from Taconic focused on Kabuki Syndrome See all of the contest winners and updates at: RareGenomics.org...

The Translational Scientist converses with Taconic's Portfolio Director Dr. John Couse about pre-clinical mouse models, specifically "how the shifting techniques and technologies in bioscience affect — and are affected by — mouse models": "The pre-clinical mouse model is an essential part of many translational medicine journeys, providing preliminary efficacy results that often determine if treatments are able to make the leap into clinical trials. With the growing...

Outsourcing-Pharma features Taconic's Dr. Gretchen Kusek who discusses Taconic mice bred specifically for a mission to the International Space Station: "Forty mice were launched into space last week aboard the SpaceX Dragon, which will deliver the genetically engineered research models to the International Space Station for study in microgravity. The mission — "Rodent Research-5" — is the result of a collaboration between the University of California, Los...

Hudson, NY — June 1, 2017 - When the SpaceX Dragon spacecraft launches today bound for the International Space Station, they will be joined by 40 special mice, bred specifically for this mission by Taconic Biosciences, a global leader in genetically engineered mouse models and associated services. The project is a collaboration between the University of California, Los Angeles (UCLA), the Center for the Advancement of Science...

The Scientist explores the relationship between the microbiome and athleticism: "Genomicist Lauren Petersen has been racing mountain bikes since she was 14 years old. But throughout her teens she battled chronic Lyme disease, suffering recurring bouts of illness that sometimes kept her off her wheels. "I'd feel like crap for a month or two, and then the antibiotics would make me feel like crap, and then I'd...

Hudson, NY — May 30, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it has signed a license agreement with ERS Genomics ("ERS") to utilize the company's CRISPR-Cas9 technology to generate unique murine models. Under the agreement, Taconic receives a worldwide non-exclusive license to the CRISPR-Cas9 patents often referred to as the "UC Berkeley patent." ERS Genomics founder, Emmanuelle...