Taconic Biosciences News

Taconic Biosciences News is your source for current and relevant news on how animal models are being used to drive drug discovery. Use the links below to explore exciting announcements from Taconic via Press Releases, Taconic’s press coverage in Publications and Media, and critical scientific insights within Industry News.

Taconic Biosciences' Animals Complete Most Recent Mission to the International Space Station

Rensselaer, NY — January 17, 2019 - Taconic Biosciences, a global leader in providing genetically engineered rodent model solutions, announces the completion of a recent mission to the International Space Station. This project represents a collaboration between the International Space Station (ISS) National Lab, National Aeronautics and Space Administration (NASA), Bioserve Space Technologies with support from the Leidos Corporation, and Taconic. Taconic has participated in several spaceflight...

Read More

Taconic Biosciences Announces R&D Collaboration with UNC-Chapel Hill

Rensselaer, NY — November 30, 2018 - Taconic Biosciences, a global leader in providing genetically engineered mouse model and service solutions, announces a research and development collaboration with the University of North Carolina at Chapel Hill (UNC). The collaboration commercializes animal model discoveries coming from the University, expanding Taconic's proprietary commercial products portfolio and ultimately increasing access to key resources necessary for developing treatments for human diseases....

Read More

Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis

An article recently divulged in Nature Communications highlights the importance of mouse models in studying the progression of pancreatic cancer, with xenograft studies performed on Taconic Biosciences' NCR nude mice. Specifically, analyzing tumors that have become resistant to KRAS or MEK inhibition is of key importance to developing anti-cancer drugs. By targeting a specific pathway of nucleotide biosynthesis, the researchers were able to reverse this resistance and...

Read More

Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13

Frontiers in Immunology features this study which discusses potential mechanisms by which schistosomes (Schistosoma mansoni) could control inflammation in a host. In order to evaluate the immune response after a Schistosoma mansoni infection, sections of S. mansoni-infected paraffin-embedded mouse liver tissue from female C57BL/6NTac mice from Taconic Biosciences were used for immunohistochemistry. Utilizing the mouse animal model was essential for furthering the research into inflammation caused by...

Read More

Mucociliary Clearance in Mice Measured by Tracking Trans-tracheal Fluorescence of Nasally Aerosolized Beads

Researchers from the University of North Carolina School of Medicine obtained Black 6 mice from Taconic Biosciences for this study on Mucociliary Clearance (MCC). The authors concluded that their technique of "tracking trans-tracheal fluorescence of nasally aerosolized beads" has multiple advantages over current techniques for studying MCC in mice: "Mucociliary clearance (MCC) is the first line of defense in clearing airways. In genetically engineered mice, each component...

Read More

Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

This article published in Nature Communications is a comprehensive report on the differences between invasive versus non-invasive glioblastoma cells. The authors used ICR scid mice sourced from Taconic Biosciences due to the absence of B and T cells in this model: "The intrinsic drivers of migration in glioblastoma (GBM) are poorly understood. To better capture the native molecular imprint of GBM and its developmental context, here we...

Read More

NIR-II fluorescence imaging using indocyanine green nanoparticles

Scientific Reports discusses a new imaging fluorescent imaging technique that is based on indocyanine green nanoparticles. The studies utilized Taconic Biosciences' NCRNU model for in vivo NIR-II imaging "...[which] was performed in the hind-limb area and the brain to study the visualization of vascular structures with and without bone interference": "Fluorescence imaging in the second near-infrared window (NIR-II) holds promise for real-time deep tissue imaging. In this...

Read More

Taconic Biosciences Becomes the First Animal Model Provider on General Services Administration Contract Schedule

Rensselaer, NY — September 20, 2018 - Taconic Biosciences, a global leader in providing genetically engineered rodent model solutions, announces a new relationship with Government Scientific Source (GSS). GSS is a leading dedicated distributor of laboratory equipment to federal, state, and local governments on contract with the GSA (General Services Administration). By having Taconic's products available via GSS, they can now be accessed by all federal agencies,...

Read More

CASIS Announces Request for Proposals to Access Spaceflight Biospecimens

In association with Taconic Biosciences and BioServe Space Technologies, selected concepts from this Request for Proposals will support Rodent Research Reference Mission-1, a CASIS-sponsored initiative to support biospecimen research onboard the International Space Station U.S. National Laboratory Kennedy Space Center, FL — September 11, 2018 - The Center for the Advancement of Science in Space (CASIS) today announced a Request for Proposals (RFP) for investigators seeking to...

Read More

Taconic Biosciences Partners with Science Exchange to Offer Online Access to its Products and Services

Palo Alto, CA — (BUSINESS WIRE) — August 21, 2018 - Science Exchange, the leading marketplace for outsourced R&D™, announced today a collaboration with Taconic Biosciences, one of the world's foremost providers of genetically engineered rodent models and services, to offer on-demand access to Taconic's entire portfolio of products and services to researchers worldwide. Founded in 1952, Taconic is one of the most experienced rodent model design...

Read More