Taconic Biosciences News

Taconic Biosciences News is your source for current and relevant news on how animal models are being used to drive drug discovery. Use the links below to explore exciting announcements from Taconic via Press Releases, Taconic’s press coverage in Publications and Media, and critical scientific insights within Industry News.

Pharmatest Launches Novel Humanised Mouse Model of Tumor Growth in Bone

Taconic is featured in this press release from Pharmatest Services,Ltd., as both have collaborated "to develop a novel humanised mouse model of tumor growth in bone that can be used for testing immunotherapies": "Testing compound efficacy in bone microenvironment should substantially decrease the very high number of cancer drugs currently failing in clinical trials due to poor efficacy. Pharmatest Services is a contract research organisation that offers...

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Microbial Influence

GenomeWeb details how researchers are experimenting with the microbiome to influence brain development: "Researchers have linked certain brain malformations to the microbiome, the New York Times reports. A team led by the University of Pennsylvania's Mark Kahn reports in Nature that the gut microbiome appears to influence the development of cerebral cavernous malformations. While these malformations — which can lead to stroke and seizures — are due...

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Guest Commentary: CRISPR--The past, present and future

Dr. Adriano Flora, an expert in the field of murine genetic design, penned this article in DDNews: "CRISPR/Cas9 is a gene-editing technology based on the ability of introducing a double-strand break in selected regions of the genome and exploiting the DNA repair systems to modify the targeted sequence. By introducing the genetic modification directly in embryos and bypassing the embryonic stem (ES) cell manipulation steps, CRISPR/Cas9 represents...

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Taconic Biosciences Expands Microbiome Portfolio

Germ Free BALB/c Mice Facilitate Discovery of New Therapeutics Hudson, NY — May 4, 2017 - Taconic Biosciences, global leader in genetically engineered mouse models and associated services and the only commercial provider of germ-free mice, announced it has added Germ Free BALB/c mice to its microbiome portfolio. The new product expands Taconic's existing collection of germ-free animal models, which includes C57BL/6 (Black 6) and Swiss Webster...

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Taconic Biosciences Announces Expansion of Key Alzheimer Animal Model

Hudson, NY — May 3, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it will expand the offering of a key Alzheimer's Disease (AD) mouse model, APPSWE - Model 1349, to include aged animals. Taconic will now offer off-the-shelf Model 1349 animals aged up to 42 weeks, saving months off the typical timeline to access Alzheimer's models. This program...

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Researchers use gene editing to eliminate HIV infection in mice

CBS News reports that for the first time researchers have successfully eliminated the HIV virus from lab mice, by means of CRISPR gene editing technology: "Have researchers taken a step closer to developing an eventual cure for HIV? A Temple University-led team hopes so, by using a gene editing technique to successfully remove HIV infection from lab mice. The gene-editing tool called CRISPR -- which allows scientists...

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More Tooth, More Tail in CRISPR Operations

This Genetic Engineering & Biotechnology news article spotlights Taconic's Adriano Flora, PhD, an expert in custom model generation: "The tooth-to-tail ratio, or the balance of frontline troops to support echelons, can determine success or failure in any complicated operation. Originally a military notion, the tooth-to-tail ratio also applies to commercial and scientific endeavors, such as the routinization of genome editing. Ideally, genome-editing technologies such as the CRISPR/Cas9...

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Taconic Biosciences Expands Microbiome Product and Service Platform

Hudson, NY — April 26, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services and the only commercial provider of germ-free mice, announced that effective April 26, 2017 they will expand their microbiome product and services platform to include custom Fecal Microbiota Transplantation (FMT) services. To support these new FMT services, Taconic will also offer custom germ-free derivations using either client...

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Taconic Biosciences Announces Release of New Parkinson's Disease Animal Model

Hudson, NY — April 25, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced that effective April 17, 2017, in conjunction with The Michael J. Fox Foundation for Parkinson's Research (MJFF), will begin commercial distribution of a new Parkinson's disease mouse Model 13940 (C57BL/6- Lrrk2tm4.1Arte). The development of Model 13940 underscores the commitment of both Taconic and MJFF to provide...

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Something old, something new... a marriage of technologies for Immuno-oncology In Vivo studies

Dr. Philip Dubé is the author of this Drug Discovery World article due to his expertise with animal models and immuno-oncology research: "Discovering & validating novel therapeutic targets to add to the immuno-oncology arsenal requires refined preclinical models that meet needs for suitability, scalability & clinical relevancy throughout the phases of target discovery & drug validation. The use of animal models in oncology has undergone a revolution...

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