Taconic Biosciences News

Outsourcing-Pharma features Taconic's Dr. Gretchen Kusek who discusses Taconic mice bred specifically for a mission to the International Space Station: "Forty mice were launched into space last week aboard the SpaceX Dragon, which will deliver the genetically engineered research models to the International Space Station for study in microgravity. The mission — "Rodent Research-5" — is the result of a collaboration between the University of California, Los...

Hudson, NY — June 1, 2017 - When the SpaceX Dragon spacecraft launches today bound for the International Space Station, they will be joined by 40 special mice, bred specifically for this mission by Taconic Biosciences, a global leader in genetically engineered mouse models and associated services. The project is a collaboration between the University of California, Los Angeles (UCLA), the Center for the Advancement of Science...

The Scientist explores the relationship between the microbiome and athleticism: "Genomicist Lauren Petersen has been racing mountain bikes since she was 14 years old. But throughout her teens she battled chronic Lyme disease, suffering recurring bouts of illness that sometimes kept her off her wheels. "I'd feel like crap for a month or two, and then the antibiotics would make me feel like crap, and then I'd...

Hudson, NY — May 30, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it has signed a license agreement with ERS Genomics ("ERS") to utilize the company's CRISPR-Cas9 technology to generate unique murine models. Under the agreement, Taconic receives a worldwide non-exclusive license to the CRISPR-Cas9 patents often referred to as the "UC Berkeley patent." ERS Genomics founder, Emmanuelle...

Lab Animal quotes Dr. Ana Perez with regards to a process that vendors perform, after there have been a number of generations of rodent research models, to delay genetic drift: "Spontaneous mutations can lead scientists down the wrong path, but awareness in academia and new measures by industry are helping to keep genetic drift at bay. Harvard immunologist Shiv Pillai was puzzled. His team was studying how...

Taconic is featured in this press release from Pharmatest Services,Ltd., as both have collaborated "to develop a novel humanised mouse model of tumor growth in bone that can be used for testing immunotherapies": "Testing compound efficacy in bone microenvironment should substantially decrease the very high number of cancer drugs currently failing in clinical trials due to poor efficacy. Pharmatest Services is a contract research organisation that offers...

GenomeWeb details how researchers are experimenting with the microbiome to influence brain development: "Researchers have linked certain brain malformations to the microbiome, the New York Times reports. A team led by the University of Pennsylvania's Mark Kahn reports in Nature that the gut microbiome appears to influence the development of cerebral cavernous malformations. While these malformations — which can lead to stroke and seizures — are due...

Dr. Adriano Flora, an expert in the field of murine genetic design, penned this article in DDNews: "CRISPR/Cas9 is a gene-editing technology based on the ability of introducing a double-strand break in selected regions of the genome and exploiting the DNA repair systems to modify the targeted sequence. By introducing the genetic modification directly in embryos and bypassing the embryonic stem (ES) cell manipulation steps, CRISPR/Cas9 represents...

Germ Free BALB/c Mice Facilitate Discovery of New Therapeutics Hudson, NY — May 4, 2017 - Taconic Biosciences, global leader in genetically engineered mouse models and associated services and the only commercial provider of germ-free mice, announced it has added Germ Free BALB/c mice to its microbiome portfolio. The new product expands Taconic's existing collection of germ-free animal models, which includes C57BL/6 (Black 6) and Swiss Webster...

Hudson, NY — May 3, 2017 - Taconic Biosciences, a global leader in genetically engineered mouse models and associated services, announced it will expand the offering of a key Alzheimer's Disease (AD) mouse model, APPSWE - Model 1349, to include aged animals. Taconic will now offer off-the-shelf Model 1349 animals aged up to 42 weeks, saving months off the typical timeline to access Alzheimer's models. This program...