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DBA/2

TRADITIONAL INBRED MICE

Model Number	Zygosity	Nomenclature
DBA2-F		DBA/2NTac
DBA2-M		DBA/2NTac

Model Description

Used in infectious disease studies, genetic studies and testing anticonvulsants
Susceptible to induced audiogenic seizures

Origin: The DBA/2 inbred model was developed by Little in 1929-1930 by intercrossing to generate new sublines, 12 (now known as DBA/1 and 212 (now known as DBA/2). NIH received stock at F34 from Midler in 1951. Midler received stock from Little in 1938. Taconic received axenic breeders at F137 from the NIH Animal Genetic Resource in 1981. The Taconic foundation colony was at F201 in 2005.

Color: Dilute Brown Non-Agouti

Coat Color Loci: a, Tyrp1^b, Myo5a^d

Genetics:

Strain Profile: Acy1^s, Alad^a, Car2^b, Ce2^a, Es1^b, Es3^c, Esd^b, H6pd^b, Ggc^a, Gpi1^a, Gus-s^b, Hbb^d, Idh1^b, Ldr1^a, Mod1^a, Mpi1^b, Mup1^a, Pepc^b, Pgm1^b, Pnp^a, Sod1^a, Trf^b
Immunology: H2^d
Other: Cd5^a, Cd72^a, Cd8a^a, Cd8b^b, H2-T18^c, Hc^c, Igh1^a, Thy-1^b