Model DB References

Aasum E, Hafstad AD, Severson DL, Larsen TS. (2003) Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. Diabetes. Feb;52(2):434-41.

Begin-Heick N, Coleman DL. (1988) Effect of the genetic background and specific mutation on adenylate cyclase activity in obesity syndromes; Mol Cell Endocrinol. Oct;59(3):171-8.

Coleman DL, Kuzava JE, Leiter EH., (1990) Effect of diet on incidence of diabetes in nonobese diabetic mice; Diabetes.Apr;39(4):432-6.

Clodfelder-Miller B, De Sarno P, Zmijewska AA, Song L, Jope RS. (2005) Physiological and Pathological Changes in Glucose Regulate Brain Akt and Glycogen Synthase Kinase-3; J Biol Chem, 280(48):39723-31.

Halseth AE, Ensor NJ, White TA, Ross SA, Gulve EA.(2002) Acute and chronic treatment of ob/ob and db/db mice with AICAR decreases blood glucose concentrations; Biochem Biophys Res Commun. Jun 21;294(4):798-805.

Madiehe AM, Mitchell TD, Harris RB. (2003) Hyperleptinemia and reduced TNF-alpha secretion cause resistance of db/db mice to endotoxin; Am J Physiol Regul Integr Comp Physiol. Mar;284(3):R763-70.

Mastropaolo MD, Evans NP, Byrnes MK, Stevens AM, Robertson JL, Melville SB. (2005) Synergy in Polymicrobial Infections in a Mouse Model of Type 2 Diabetes; Infect Immun, 73(9):6055-63.

Nagakura T, Yasuda N, Yamazaki K, Ikuta H, Tanaka I. (2003) Enteroinsular axis of db/db mice and efficacy of dipeptidyl peptidase IV inhibition; Metabolism. Jan;52(1):81-6.

Nonomura T, Tsuchida A, Ono-Kishino M, Nakagawa T, Taiji M, Noguchi H. (2001) Brain-derived neurotrophic factor regulates energy expenditure through the central nervous system in obese diabetic mice; Int J Exp Diabetes Res.;2(3):201-9.

Saaristo A, Tammela T, Frkkil A, K?rkk?inen M, Suominen E, Yla-Herttuala S, Alitalo K. (2006) Vascular Endothelial Growth Factor-C Accelerates Diabetic Wound Healing. American Journal of Pathology, 169(3):1080-7.

Susztak K, Ciccone E, McCue P, Sharma K, B?ttinger EP. (2005) Multiple Metabolic Hits Converge on CD36 as Novel Mediator of Tubular Epithelial Apoptosis in Diabetic Nephropathy; PloS Med, 2(2):e45.

Timmers K, Coleman DL, Voyles NR, Powell AM, Rokaeus A, Recant L. (1990) Neuropeptide content in pancreas and pituitary of obese and diabetes mutant mice: strain and sex differences; Metabolism. Apr;39(4):378-83.

Timmers KI, Palkovits M, Coleman DL. (1990) Unique alterations of neuropeptide content in median eminence, amygdala, and dorsal vagal complex of 3- and 6-week-old diabetes mutant mice; Metabolism Nov;39(11):1158-66.

Yamashita H, Shao J, Qiao L, Pagliassotti M, Friedman JE. (2003) Effect of spontaneous gestational diabetes on fetal and postnatal hepatic insulin resistance in Lepr(db/+) mice; Pediatr Res. Mar;53(3):411-8.

Yoon JW, Leiter EH, Coleman DL, Kim MK, Pak CY, McArthur RG, Roncari DA. (1988) Genetic control of organ-reactive autoantibody production in mice by obesity (ob) diabetes (db) genes; Diabetes. Sep;37(9):1287-93.