TKO™ Rat Repository Models

Laboratory rats with a single gene trap insertion created using mobile DNA technology.

The TKO™ Rat Repository of ~90 knockout* rat lines provides commercial researchers worldwide with unparalleled access to fully-licensed, newly available knockout rat models. Our repository offers the scientific community immediate access to highly valuable research tools that rapidly accelerate the drug discovery and development processes.

*Please note: all TKO™ Rat lines are predicted to be knockouts, but complete knockout has not been confirmed by Western blot in most cases.

The following list gives gene name, catalog number and research application (where known).

Abat - Catalog # TK0001 - CNS & Neurological Disorders
 

Agbl4 - Catalog # TK0003
 

Auts2 - Catalog # TK0005
 

AW915325 - Catalog # TK0006
 

Bbx - Catalog # TK0007
 

BE329202 - Catalog # TK0008
 

BF522453 - Catalog # TK0009
 

BI284934 - Catalog # TK0010
 

Ccdc85a - Catalog # TK0012
 

Cd226 - Catalog # TK0013 - Immune & Cardiovascular Disorders
 

Chsy1 - Catalog # TK0016
 

Csmd3 - Catalog # TK0017
 

Cyp7b1 - Catalog # TK0018 - CNS, Metabolic, ADME, & Toxicology Disorders
 

Cyyr1 - Catalog # TK0019
 

Dcc - Catalog # TK0020 - Cancer & Gastrointestinal Disorders
 

Diaph3 - Catalog # TK0021
 

Dnah11 - Catalog # TK0022 - Respiratory Disorders
 

Elmod3 - Catalog # TK0071
 

EST FM117003 - Catalog # TK0030
 

Exoc4 - Catalog # TK0024
 

Fam19a2 - Catalog # TK0045
 

Fam5c - Catalog # TK0011
 

Galntl6 - Catalog # TK0025
 

Gng12 - Catalog # TK0026
 

Gramd1b - Catalog # TK0027
 

Grk1 - Catalog # TK0028 - CNS & Cardiovascular Disorders
 

Immp1l - Catalog # TK0029
 

Inadl - Catalog # TK0031
 

Inpp4b - Catalog # TK0032 - Endocrine & Metabolic Disorders
 

Intu - Catalog # TK0033
 

Kcnab1 - Catalog # TK0034
 

Kcnh7 - Catalog # TK0035 - CNS & Inflammatory Disorders
 

Kcnip4 - Catalog # TK0036 - CNS & Neurological Disorders
 

Kif16b - Catalog # TK0037
 

Klra2 - Catalog # TK0038
 

Lama2 - Catalog #TK0039 - CNS & Neurological Disorders
 

Leprel2 - Catalog # TK0040
 

Lims1 - Catalog # TK0041 - CNS & Cancer
 

Lmln - Catalog # TK0042
 

LOC290071 - Catalog # TK0043
 

LOC685444 - Catalog # TK0046
 

Lphn3 - Catalog # TK0047
 

Lrrc4c - Catalog # TK0048
 

Lrrc7 - Catalog # TK0049 - Metabolic & Urogenital Disorders
 

Lzic - Catalog # TK0050
 

Mgat4c - Catalog # TK0051
 

Mmel1 - Catalog # TK0052
 

Myo1d - Catalog # TK0055
 

Myo9a - Catalog # TK0056
 

Napb - Catalog # TK0044
 

Nsun4 - Catalog # TK0058
 

Orc3I - Catalog # TK0059 - CNS & Neurological Disorders
 

Pebp4 - Catalog # TK0061 - Cancer
 

Plcb3 - Catalog # TK0062 - CNS, Cardiovascular & Metabolic Disorders
 

Plce1 - Catalog # TK0063 - CNS & Urogenital Disorders
 

Pld5 - Catalog # TK0064
 

Ppapdc1a - Catalog # TK0065
 

Ppfia2 - Catalog # TK0066 - Cancer
 

Ptpra - Catalog # TK0067 - Inflammatory
 

Pvrl1 - Catalog # TK0068
 

Rap1gds1 - Catalog # TK0069
 

Rapgef4 - Catalog # TK0070 - CNS, Endocrine & Metabolic Disorders
 

RGD1309969 - Catalog # TK0072
 

RGD131073 - Catalog # TK0073
 

RGD131073 - Catalog # TK0074
 

RGD1563503 - Catalog # TK0015
 

RGD1565323 - Catalog # TK0054
 

Robo1 - Catalog # TK0075
 

Rph3a - Catalog # TK0076 - CNS & Neurological Disorders
 

Rtn4 - Catalog # TK0077
 

Sf4 - Catalog # TK0078
 

Slc16a12 - Catalog # TK0079 - CNS & neurological, ADME, toxicology & ocular disorders
 

Slc7a11 - Catalog # TK0080 - Respiratory, Urogenital, ADME & Toxicology Disorders
 

Snx25 - Catalog # TK0081 - Cancer
 

Spata13 - Catalog # TK0082 - Cancer and Gastrointestinal Disorders
 

Spta1 - Catalog # TK0083
 

Sptlc3 - Catalog # TK0084
 

Stxbp5I - Catalog # TK0085
 

Syne1 - Catalog # TK0086 - CNS & Neurological Disorders
 

Tmem22 - Catalog # TK0087
 

Tmtc2 - Catalog # TK0088
 

Trdn - Catalog # TK0089 - Cardiovascular & Inflammatory Disorders
 

Ubqln4 - Catalog # TK0090 - CNS & Neurological Disorders
 

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