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Feith DJ, et al.
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Feith DJ, Shantz LM, Pegg AE
(2001) Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis. Cancer Res. 61(16):6073-81
Ziegler SF, et al.
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Ziegler SF, Wilkinson JE, Paeper B, Brunkow ME, Ramsdell F, Jeffery EW, Hjerrild KA, Clark LB, Yasayko SA, Galas D
(2001) Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27(1):68-73
Asamoto M, et al.
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Asamoto M, Hokaiwado N, Cho YM, Takahashi S, Ikeda Y, Imaida K, Shirai T
(2001) Prostate carcinomas developing in transgenic rats with SV40 T antigen expression under probasin promoter control are strictly androgen dependent. Cancer Res. 61(12):4693-700
Tanemura K, et al.
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Tanemura K, Murayama M, Akagi T, Hashikawa T, Tominaga T, Ichikawa M, Yamaguchi H, Takashima A
(2002) Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. J. Neurosci. 22(1):133-41
Sakata Y, et al.
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Sakata Y, Kamei CN, Nakagami H, Bronson R, Liao JK, Chin MT
(2002) Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2. Proc. Natl. Acad. Sci. U.S.A. 99(25):16197-202
Wagenaar E, et al.
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Wagenaar E, Jonker JW, Beijnen JH, van der Valk MA, Scheffer GL, Scheper RJ, Elferink RP, Rosing H, Buitelaar M, Kuipers F, Schinkel AH., Plösch T
(2002) The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria Proc Natl Acad Sci USA. 99(24):15649-54.
Breast Cancer
Engle SJ, et al.
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Engle SJ, Ormsby I, Pawlowski S, Boivin GP, Croft J, Balish E, Doetschman T
(2002) Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice. Cancer Res. 62(22):6362-6
Colon Cancer
Eggan K, et al.
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Eggan K, Rode A, Jentsch I, Samuel C, Hennek T, Tintrup H, Zevnik B, Erwin J, Loring J, Jackson-Grusby L, Speicher MR, Kuehn R, Jaenisch R
(2002) Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat. Biotechnol. 20(5):455-9
Stem Cells/Regenerative Medicine/Tissue Engineering
Asamoto M, et al.
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Asamoto M, Hokaiwado N, Cho YM, Shirai T
(2002) Effects of genetic background on prostate and taste bud carcinogenesis due to SV40 T antigen expression under probasin gene promoter control. Carcinogenesis 23(3):463-7
Andreas S, et al.
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Andreas S, Schwenk F, Küter-Luks B, Faust N, Kühn R
(2002) Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells. Nucleic Acids Res. 30(11):2299-306
Anderson RE, et al.
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Anderson RE, Maude MB, McClellan M, Matthes MT, Yasumura D, LaVail MM
(2002) Low docosahexaenoic acid levels in rod outer segments of rats with P23H and S334ter rhodopsin mutations. Mol. Vis. 8:351-8
Zhang Y, et al.
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Zhang Y, Rauch U, Perez MT
(2003) Accumulation of neurocan, a brain chondroitin sulfate proteoglycan, in association with the retinal vasculature in RCS rats. Invest. Ophthalmol. Vis. Sci. 44(3):1252-61
Zhang Y, et al.
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Zhang Y, Arnér K, Ehinger B, Perez MT
(2003) Limitation of anatomical integration between subretinal transplants and the host retina. Invest. Ophthalmol. Vis. Sci. 44(1):324-31
Yu C, et al.
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Yu C, Staehling-Hampton K, Brunkow ME, Jonas M, Latham JA, Winkler DG, Sutherland MK, Geoghegan JC, Hayes T, Skonier JE, Shpektor D, Kovacevich BR, Appleby M
(2003) Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J. 22(23):6267-76
Tietge UJ, et al.
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Tietge UJ, Maugeais C, Cain W, Rader DJ
(2003) Acute inflammation increases selective uptake of HDL cholesteryl esters into adrenals of mice overexpressing human sPLA2. Am. J. Physiol. Endocrinol. Metab. 285(2):E403-11
Stricklett PK, et al.
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Stricklett PK, Taylor D, Nelson RD, Kohan DE
(2003) Thick ascending limb-specific expression of Cre recombinase. Am. J. Physiol. Renal Physiol. 285(1):F33-9
Seibler J, et al.
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Seibler J, Zevnik B, Küter-Luks B, Andreas S, Kern H, Hennek T, Rode A, Heimann C, Faust N, Kauselmann G, Schoor M, Jaenisch R, Rajewsky K, Kühn R, Schwenk F
(2003) Rapid generation of inducible mouse mutants. Nucleic Acids Res. 31(4):e12
Schwenk F, et al.
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Schwenk F, Zevnik B, Brüning J, Röhl M, Willuweit A, Rode A, Hennek T, Kauselmann G, Jaenisch R, Kühn R
(2003) Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics. Mol. Cell. Biol. 23(11):3982-9
Sagdullaev BT, et al.
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Sagdullaev BT, Aramant RB, Seiler MJ, Woch G, McCall MA
(2003) Retinal transplantation-induced recovery of retinotectal visual function in a rodent model of retinitis pigmentosa. Invest. Ophthalmol. Vis. Sci. 44(4):1686-95
Phan TG, et al.
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Phan TG, Amesbury M, Gardam S, Crosbie J, Hasbold J, Hodgkin PD, Basten A, Brink R
(2003) B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J. Exp. Med. 197(7):845-60
Lozano J, et al.
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Lozano J, Xing R, Cai Z, Jensen HL, Trempus C, Mark W, Cannon R, Kolesnick R
(2003) Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice. Cancer Res. 63(14):4232-8
Lee JH, et al.
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Lee JH, Lau KF, Perkinton MS, Standen CL, Shemilt SJ, Mercken L, Cooper JD, McLoughlin DM, Miller CC
(2003) The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice. J. Biol. Chem. 278(47):47025-9
Alzheimer's
Kühn R, et al.
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Kühn R, Schwenk F
(2003) Conditional knockout mice. Methods Mol. Biol. 209:159-85
Wagenaar E, et al.
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Wagenaar E, Jonker JW, Van Eijl S, Schinkel AH.
(2003) Deficiency in the Organic Cation Transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in Mice Abolishes Renal Secretion of Organic Cations Mol Cell Biol. 23(21):7902-7908.
Czipri M, et al.
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Czipri M, Otto JM, Cs-Szabó G, Kamath RV, Vermes C, Firneisz G, Kolman KJ, Watanabe H, Li Y, Roughley PJ, Yamada Y, Olsen BR, Glant TT
(2003) Genetic rescue of chondrodysplasia and the perinatal lethal effect of cartilage link protein deficiency. J. Biol. Chem. 278(40):39214-23
Crocker SJ, et al.
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Crocker SJ, Liston P, Anisman H, Lee CJ, Smith PD, Earl N, Thompson CS, Park DS, Korneluk RG, Robertson GS
(2003) Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice. Neurobiol. Dis. 12(2):150-61
Zhang W, et al.
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Zhang W, Purchio AF, Coffee R, West DB
(2004) Differential regulation of the human CYP3A4 promoter in transgenic mice and rats. Drug Metab. Dispos. 32(2):163-7
Otani K, et al.
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Otani K, Han DH, Ford EL, Garcia-Roves PM, Ye H, Horikawa Y, Bell GI, Holloszy JO, Polonsky KS
(2004) Calpain system regulates muscle mass and glucose transporter GLUT4 turnover. J. Biol. Chem. 279(20):20915-20
Lee JH, et al.
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Lee JH, Lau KF, Perkinton MS, Standen CL, Rogelj B, Falinska A, McLoughlin DM, Miller CC
(2004) The neuronal adaptor protein X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice. J. Biol. Chem. 279(47):49099-104
Hess JF, et al.
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Hess JF, Ransom RW, Zeng Z, Chang RS, Hey PJ, Warren L, Harrell CM, Murphy KL, Chen TB, Miller PJ, Lis E, Reiss D, Gibson RE, Markowitz MK, DiPardo RM, Su DS, Bock MG, Gould RJ, Pettibone DJ
(2004) Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model. J. Pharmacol. Exp. Ther. 310(2):488-97
Griffin KJ, et al.
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Griffin KJ, Kirschner LS, Matyakhina L, Stergiopoulos S, Robinson-White A, Lenherr S, Weinberg FD, Claflin E, Meoli E, Cho-Chung YS, Stratakis CA
(2004) Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors. Cancer Res. 64(24):8811-5
Humanization
Oncology
García-Martínez LF, et al.
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García-Martínez LF, Appleby MW, Staehling-Hampton K, Andrews DM, Chen Y, McEuen M, Tang P, Rhinehart RL, Proll S, Paeper B, Brunkow ME, Grandea AG, Howard ED, Walker DE, Charmley P, Jonas M, Shaw S, Latham JA, Ramsdell F
(2004) A novel mutation in CD83 results in the development of a unique population of CD4+ T cells. J. Immunol. 173(5):2995-3001
Finkle D, et al.
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Finkle D, Quan ZR, Asghari V, Kloss J, Ghaboosi N, Mai E, Wong WL, Hollingshead P, Schwall R, Koeppen H, Erickson S
(2004) HER2-targeted therapy reduces incidence and progression of midlife mammary tumors in female murine mammary tumor virus huHER2-transgenic mice. Clin. Cancer Res. 10(7):2499-511
Butler AE, et al.
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Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC
(2004) Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes. Diabetes 53(6):1509-16
Autoimmune
Seibler J, et al.
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Seibler J, Küter-Luks B, Kern H, Streu S, Plum L, Mauer J, Kühn R, Brüning JC, Schwenk F
(2005) Single copy shRNA configuration for ubiquitous gene knockdown in mice. Nucleic Acids Res. 33(7):e67
Jonker JW, et al.
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Jonker JW, Freeman J, Bolscher E, Musters S, Alvi AJ, Titley I, Schinkel AH, Dale TC
(2005) Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice. Stem Cells 23(8):1059-65
Irvine RA, et al.
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Irvine RA, Adachi N, Shibata DK, Cassell GD, Yu K, Karanjawala ZE, Hsieh CL, Lieber MR
(2005) Generation and characterization of endonuclease G null mice. Mol. Cell. Biol. 25(1):294-302
Andrews ZB, et al.
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Andrews ZB, Horvath B, Barnstable CJ, Elsworth J, Elseworth J, Yang L, Beal MF, Roth RH, Matthews RT, Horvath TL
(2005) Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. J. Neurosci. 25(1):184-91
Parkinson's
Stanley LA, et al.
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Stanley LA, Horsburgh BC, Ross J, Scheer N, Wolf CR
(2006) PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity. Drug Metab. Rev. 38(3):515-97
Plum L, et al.
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Plum L, Ma X, Hampel B, Balthasar N, Coppari R, Münzberg H, Shanabrough M, Burdakov D, Rother E, Janoschek R, Alber J, Belgardt BF, Koch L, Seibler J, Schwenk F, Fekete C, Suzuki A, Mak TW, Krone W, Horvath TL, Ashcroft FM, Brüning JC
(2006) Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. J. Clin. Invest. 116(7):1886-901
Organisciak D, et al.
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Organisciak D, Darrow R, Gu X, Barsalou L, Crabb JW
(2006) Genetic, age and light mediated effects on crystallin protein expression in the retina. Photochem. Photobiol. 82(4):1088-96
Ma Y, et al.
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Ma Y, Hu H, Berrebi AS, Mathers PH, Agmon A
(2006) Distinct subtypes of somatostatin-containing neocortical interneurons revealed in transgenic mice. J. Neurosci. 26(19):5069-82
Lee G, et al.
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Lee G, Lo A, Short SA, Mankelow TJ, Spring F, Parsons SF, Yazdanbakhsh K, Mohandas N, Anstee DJ, Chasis JA
(2006) Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood 108(6):2064-71
Krimm RF
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Krimm RF
(2006) Mice lacking the p75 receptor fail to acquire a normal complement of taste buds and geniculate ganglion neurons by adulthood. Anat Rec A Discov Mol Cell Evol Biol 288(12):1294-302
Cheng S, et al.
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Cheng S, Pollock AS, Mahimkar R, Olson JL, Lovett DH
(2006) Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury. FASEB J. 20(11):1898-900
Yaradanakul A, et al.
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Yaradanakul A, Feng S, Shen C, Lariccia V, Lin MJ, Yang J, Kang T M , Dong P, Yin HL, Albanesi JP, Hilgemann DW
(2007) Dual control of cardiac Na+ Ca2+ exchange by PIP(2): electrophysiological analysis of direct and indirect mechanisms. J. Physiol. (Lond.) 582(Pt 3):991-1010
van Herwaarden AE, et al.
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van Herwaarden AE, Wagenaar E, Beijnen JH, Smit JW, van Tellingen O, van der Valk MA, Rosing H, van der Kruijssen CM, van Waterschoot RA, Song JY, van der Hoorn JW, Schinkel AH.
(2007) Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism J Clin Invest. 117(11):3583-92.
Woodruff ML, et al.
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Woodruff ML, Olshevskaya EV, Savchenko AB, Peshenko IV, Barrett R, Bush RA, Sieving PA, Fain GL, Dizhoor AM
(2007) Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark. J. Neurosci. 27(33):8805-15
Thomas BB, et al.
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Thomas BB, Samant DM, Seiler MJ, Aramant RB, Sheikholeslami S, Zhang K, Chen Z, Sadda SR
(2007) Behavioral evaluation of visual function of rats using a visual discrimination apparatus. J. Neurosci. Methods 162(1-2):84-90
Thomas BB, et al.
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Thomas BB, Seiler MJ, Aramant RB, Samant D, Qiu G, Vyas N, Arai S, Chen Z, Sadda SR
(2007) Visual functional effects of constant blue light in a retinal degenerate rat model. Photochem. Photobiol. 83(3):759-65
Seibler J, et al.
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Seibler J, Kleinridders A, Küter-Luks B, Niehaves S, Brüning JC, Schwenk F
(2007) Reversible gene knockdown in mice using a tight, inducible shRNA expression system. Nucleic Acids Res. 35(7):e54
Schmitt I, et al.
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Schmitt I, Linden M, Khazneh H, Evert BO, Breuer P, Klockgether T, Wuellner U
(2007) Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination. Biochem. Biophys. Res. Commun. 362(3):734-9
Qiu G, et al.
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Qiu G, Seiler MJ, Thomas BB, Wu K, Radosevich M, Sadda SR
(2007) Revisiting nestin expression in retinal progenitor cells in vitro and after transplantation in vivo. Exp. Eye Res. 84(6):1047-59
Peng Q, et al.
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Peng Q, Thomas BB, Aramant RB, Chen Z, Sadda SR, Seiler MJ
(2007) Structure and function of embryonic rat retinal sheet transplants. Curr. Eye Res. 32(9):781-9
Park JM, et al.
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Park JM, Kanaoka Y, Eguchi N, Aritake K, Grujic S, Materi AM, Buslon VS, Tippin BL, Kwong AM, Salido E, French SW, Urade Y, Lin HJ
(2007) Hematopoietic prostaglandin D synthase suppresses intestinal adenomas in ApcMin/+ mice. Cancer Res. 67(3):881-9
Li N, et al.
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Li N, Cui Z, Fang F, Lee JY, Ballatori N
(2007) Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter. Biochem. J. 407(3):363-72
Cheatham MA, et al.
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Cheatham MA, Zheng J, Huynh KH, Du GG, Edge RM, Anderson CT, Zuo J, Ryan AF, Dallos P
(2007) Evaluation of an independent prestin mouse model derived from the 129S1 strain. Audiol. Neurootol. 12(6):378-90
Bemis JC, et al.
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Bemis JC, Alejandro NF, Nazarenko DA, Brooks AI, Baggs RB, Gasiewicz TA
(2007) TCDD-induced alterations in gene expression profiles of the developing mouse paw do not influence morphological differentiation of this potential target tissue. Toxicol. Sci. 95(1):240-8
Xu D, et al.
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Xu D, Rowland SE, Clark P, Giroux A, Côté B, Guiral S, Salem M, Ducharme Y, Friesen RW, Méthot N, Mancini J, Audoly L, Riendeau D
(2008) MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation. J. Pharmacol. Exp. Ther. 326(3):754-63
Seiler MJ, et al.
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Seiler MJ, Thomas BB, Chen Z, Arai S, Chadalavada S, Mahoney MJ, Sadda SR, Aramant RB
(2008) BDNF-treated retinal progenitor sheets transplanted to degenerate rats: improved restoration of visual function. Exp. Eye Res. 86(1):92-104
Scheer N, et al.
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Scheer N, Ross J, Rode A, Zevnik B, Niehaves S, Faust N, Wolf CR
(2008) A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. J. Clin. Invest. 118(9):3228-39
Pettigrew LC, et al.
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Pettigrew LC, Kindy MS, Scheff S, Springer JE, Kryscio RJ, Li Y, Grass DS
(2008) Focal cerebral ischemia in the TNFalpha-transgenic rat. J Neuroinflammation 5:47
Pennesi ME, et al.
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Pennesi ME, Nishikawa S, Matthes MT, Yasumura D, LaVail MM
(2008) The relationship of photoreceptor degeneration to retinal vascular development and loss in mutant rhodopsin transgenic and RCS rats. Exp. Eye Res. 87(6):561-70
Menke DB, et al.
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Menke DB, Guenther C, Kingsley DM
(2008) Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs. Development 135(15):2543-53
Lu H, et al.
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Lu H, Choudhuri S, Ogura K, Csanaky IL, Lei X, Cheng X, Song PZ, Klaassen CD
(2008) Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR. Toxicol. Sci. 103(1):35-45
Koch L, et al.
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Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant G, Kahn CR, Schwenk F, Brüning JC
(2008) Central insulin action regulates peripheral glucose and fat metabolism in mice. J. Clin. Invest. 118(6):2132-47
Herold MJ, et al.
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Herold MJ, van den Brandt J, Seibler J, Reichardt HM
(2008) Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats. Proc. Natl. Acad. Sci. U.S.A. 105(47):18507-12
Gwack Y, et al.
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Gwack Y, Srikanth S, Oh-Hora M, Hogan PG, Lamperti ED, Yamashita M, Gelinas C, Neems DS, Sasaki Y, Feske S, Prakriya M, Rajewsky K, Rao A
(2008) Hair loss and defective T- and B-cell function in mice lacking ORAI1. Mol. Cell. Biol. 28(17):5209-22
T And/Or B Cell Function
Gutierrez JA, et al.
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Gutierrez JA, Solenberg PJ, Perkins DR, Willency JA, Knierman MD, Jin Z, Witcher DR, Luo S, Onyia JE, Hale JE
(2008) Ghrelin octanoylation mediated by an orphan lipid transferase. Proc. Natl. Acad. Sci. U.S.A. 105(17):6320-5
Guenther C, et al.
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Guenther C, Pantalena-Filho L, Kingsley DM
(2008) Shaping skeletal growth by modular regulatory elements in the Bmp5 gene. PLoS Genet. 4(12):e1000308
Christoph T, et al.
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Christoph T, Bahrenberg G, De Vry J, Englberger W, Erdmann VA, Frech M, Kögel B, Röhl T, Schiene K, Schröder W, Seibler J, Kurreck J
(2008) Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice. Mol. Cell. Neurosci. 37(3):579-89
Chi LY, et al.
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Chi LY, Yu J, Zhu H, Li XG, Zhu SG, Kindy MS
(2008) The dual role of tumor necrosis factor-alpha in the pathophysiology of spinal cord injury. Neurosci. Lett. 438(2):174-9
Ballatori N, et al.
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Ballatori N, Fang F, Christian WV, Li N, Hammond CL
(2008) Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Am. J. Physiol. Gastrointest. Liver Physiol. 295(1):G179-G186
Willuweit A, et al.
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Willuweit A, Velden J, Godemann R, Manook A, Jetzek F, Tintrup H, Kauselmann G, Zevnik B, Henriksen G, Drzezga A, Pohlner J, Schoor M, Kemp JA, von der Kammer H
(2009) Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease. PLoS ONE 4(11):e7931
Alzheimer's
van de Steeg E, et al.
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van de Steeg E, van der Kruijssen CM, Wagenaar E, Burggraaff JE, Mesman E, Kenworthy KE, Schinkel AH
(2009) Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1). Drug Metab. Dispos. 37(2):277-81
van Waterschoot RA, et al.
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van Waterschoot RA, Rooswinkel RW, Wagenaar E, van der Kruijssen CM, van Herwaarden AE, Schinkel AH
(2009) Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J. 23(1):224-31
van Herwaarden AE, et al.
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van Herwaarden AE, Beijnen JH, Sparidans RW, Rooswinkel RW, van Waterschoot RAB, Schinkel AH.
(2009) Inhibition and Stimulation of Intestinal and Hepatic CYP3A Activity: Studies in Humanized CYP3A4 Transgenic Mice Using Triazolam Drug Metab Dispos. 37:2305-2313.
Stanley LA, et al.
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Stanley LA, Horsburgh BC, Ross J, Scheer N, Wolf CR
(2009) Drug transporters: gatekeepers controlling access of xenobiotics to the cellular interior. Drug Metab. Rev. 41(1):27-65
Roebuck BD, et al.
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Roebuck BD, Johnson DN, Sutter CH, Egner PA, Scholl PF, Friesen MD, Baumgartner KJ, Ware NM, Bodreddigari S, Groopman JD, Kensler TW, Sutter TR
(2009) Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat. Toxicol. Sci. 109(1):41-9
Preitner F, et al.
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Preitner F, Bonny O, Laverrière A, Rotman S, Firsov D, Da Costa A, Metref S, Thorens B
(2009) Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc. Natl. Acad. Sci. U.S.A. 106(36):15501-6
Ooe N, et al.
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Ooe N, Motonaga K, Kobayashi K, Saito K, Kaneko H
(2009) Functional characterization of basic helix-loop-helix-PAS type transcription factor NXF in vivo: putative involvement in an "on demand" neuroprotection system. J. Biol. Chem. 284(2):1057-63
Otto C, et al.
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Otto C, Fuchs I, Kauselmann G, Kern H, Zevnik B, Andreasen P, Schwarz G, Altmann H, Klewer M, Schoor M, Vonk R, Fritzemeier KH
(2009) GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol. Reprod. 80(1):34-41
Niel L, et al.
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Niel L, Shah AH, Lewis GA, Mo K, Chatterjee D, Fernando SM, Hong MH, Chang WY, Vollmayr P, Rosen J, Miner JN, Monks DA
(2009) Sexual differentiation of the spinal nucleus of the bulbocavernosus is not mediated solely by androgen receptors in muscle fibers. Endocrinology 150(7):3207-13
Lee HW, et al.
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Lee HW, Verlander JW, Bishop JM, Igarashi P, Handlogten ME, Weiner ID
(2009) Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion. Am. J. Physiol. Renal Physiol. 296(6):F1364-75
Kotnik K, et al.
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