Pdgfrb-Cre Mouse

Random Transgenic

Pdgfrb-Cre Random Transgenic Mouse Model
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • 13075-F
  • 13075-M
  • Tissue specific cre deleter
  • Expresses cre recombinase under the control of the Pdgfrb promoter
  • Permits cre recombination in pericytes and smooth vascular muscle cells
  • May be useful for angiogenesis studies


The Pdgfrb-Cre Mouse was developed in the laboratory of Ralf Adams at the London Research Institute. The model was generated by microinjecting a transgene containing a genomic Pdgfrb promoter fragment fused to cre recombinase and a polyA sequence, into 129/B6 zygotes. Founder lines were maintained on a mixed 129;B6 background. Taconic received embryos from CRT in 2013.


Sponsor: Cancer Research Technology


This model is available for immediate cryorecovery. 



Initial Publication:

Foo SS, Turner CJ, Adams S, Compagni A, Aubyn D, Kogata N, Lindblom P, Shani M, Zicha D, Adams RH. (2006) Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 124(1):161-73.  

Access to this model requires execution of a Limited Breeding Agreement and cryorecovery services to recover the line. Current Limited Breeding Agreement fees for this model are $2,500/year (€2000/year) for nonprofit users and $10,000/year (€8000) for for-profit users. Cryorecovery fees are additional.