Tlr7

Constitutive Knock Out

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF3387
    Inquire
    MGI:2176882
Gene Description: toll-like receptor 7

Gene Family:

Membrane

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_133211

Mutation Type:

Targeted

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/12466851
http://www.ncbi.nlm.nih.gov/pubmed/12819136
http://www.ncbi.nlm.nih.gov/pubmed/15034168
http://www.ncbi.nlm.nih.gov/pubmed/14976261
http://www.ncbi.nlm.nih.gov/pubmed/11812998
http://www.ncbi.nlm.nih.gov/pubmed/15210814
http://www.ncbi.nlm.nih.gov/pubmed/15561968
http://www.ncbi.nlm.nih.gov/pubmed/15630134
http://www.ncbi.nlm.nih.gov/pubmed/15634897
http://www.ncbi.nlm.nih.gov/pubmed/15654326
http://www.ncbi.nlm.nih.gov/pubmed/16039576
http://www.ncbi.nlm.nih.gov/pubmed/12730667
http://www.ncbi.nlm.nih.gov/pubmed/16105838
http://www.ncbi.nlm.nih.gov/pubmed/16973388
http://www.ncbi.nlm.nih.gov/pubmed/16973389
http://www.ncbi.nlm.nih.gov/pubmed/12032557
http://www.ncbi.nlm.nih.gov/pubmed/16810635
http://www.ncbi.nlm.nih.gov/pubmed/17135446
http://www.ncbi.nlm.nih.gov/pubmed/17111347
http://www.ncbi.nlm.nih.gov/pubmed/17040905
http://www.ncbi.nlm.nih.gov/pubmed/17008311
http://www.ncbi.nlm.nih.gov/pubmed/17289654
http://www.ncbi.nlm.nih.gov/pubmed/16260486
http://www.ncbi.nlm.nih.gov/pubmed/16461338
http://www.ncbi.nlm.nih.gov/pubmed/17572686
http://www.ncbi.nlm.nih.gov/pubmed/17981792
http://www.ncbi.nlm.nih.gov/pubmed/18097414
http://www.ncbi.nlm.nih.gov/pubmed/16368889
http://www.ncbi.nlm.nih.gov/pubmed/18368052
http://www.ncbi.nlm.nih.gov/pubmed/18424698
http://www.ncbi.nlm.nih.gov/pubmed/18337753
http://www.ncbi.nlm.nih.gov/pubmed/18492657
http://www.ncbi.nlm.nih.gov/pubmed/15723075
http://www.ncbi.nlm.nih.gov/pubmed/16141072
http://www.ncbi.nlm.nih.gov/pubmed/16230478
http://www.ncbi.nlm.nih.gov/pubmed/17456769
http://www.ncbi.nlm.nih.gov/pubmed/18250459
http://www.ncbi.nlm.nih.gov/pubmed/18250417
http://www.ncbi.nlm.nih.gov/pubmed/18521959
http://www.ncbi.nlm.nih.gov/pubmed/18581336
http://www.ncbi.nlm.nih.gov/pubmed/14976262
http://www.ncbi.nlm.nih.gov/pubmed/17950005
http://www.ncbi.nlm.nih.gov/pubmed/18490763
http://www.ncbi.nlm.nih.gov/pubmed/16886064

 


The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) Mutant Mice, heterozygous for the Selected Mutation, including at least one (1) breeding pair on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data

Commercial Pricing:

Number of Lines PurchasedPrice per Line ($)Price per Line for Comprehensive Phenotype Data ($)
Single Line 45,000 25,000
2 Lines 40,500 25,000
3 Lines 39,375 25,000
4+ Lines 38,250 25,000

Nonprofit Pricing:

Price per Line ($)Price per Line for Comprehensive Phenotype Data ($)
30,000 15,000
Basic Phenotype Package: $5,000
Multi-line discounts will be applied to lines ordered on a single purchase order (PO).

Commercial Pricing:

Number of Lines PurchasedPrice per Line (€)Price per Line for Comprehensive Phenotype Data (€)
Single Line 42,750 23,750
2 Lines 38,475 23,750
3 Lines 37,406 23,750
4+ Lines 36,338 23,750

Nonprofit Pricing:

Price per Line (€)Price per Line for Comprehensive Phenotype Data (€)
28,500 14,250
Basic Phenotype Package: €4,750
Multi-line discounts will be applied to lines ordered on a single purchase order (PO).