Klrk1

Constitutive Knock Out

Cryopreserved Model
This line is cryopreserved and requires cryorecovery.

  • Model #
  • Genotype
  • Nomenclature
  • TF3357
    Inquire
    MGI:1196250
Gene Description: killer cell lectin-like receptor subfamily K, member 1

Synonyms: D6H12S2489E, Nkg2d, NKG2-D

Gene Family:

Membrane

Genetic Background:

129/SvEv-C57BL/6

Gene Accession Number:

NM_033078

Mutation Type:

Targeted

Species:

Mouse

Initial Publication:

http://www.ncbi.nlm.nih.gov/pubmed/9464811
http://www.ncbi.nlm.nih.gov/pubmed/9600963
http://www.ncbi.nlm.nih.gov/pubmed/10438936
http://www.ncbi.nlm.nih.gov/pubmed/10464175
http://www.ncbi.nlm.nih.gov/pubmed/10860661
http://www.ncbi.nlm.nih.gov/pubmed/10601355
http://www.ncbi.nlm.nih.gov/pubmed/12150888
http://www.ncbi.nlm.nih.gov/pubmed/12426564
http://www.ncbi.nlm.nih.gov/pubmed/12645935
http://www.ncbi.nlm.nih.gov/pubmed/14523385
http://www.ncbi.nlm.nih.gov/pubmed/14764662
http://www.ncbi.nlm.nih.gov/pubmed/15238421
http://www.ncbi.nlm.nih.gov/pubmed/15328154
http://www.ncbi.nlm.nih.gov/pubmed/15746162
http://www.ncbi.nlm.nih.gov/pubmed/16116470
http://www.ncbi.nlm.nih.gov/pubmed/16002667
http://www.ncbi.nlm.nih.gov/pubmed/16470377
http://www.ncbi.nlm.nih.gov/pubmed/16973387
http://www.ncbi.nlm.nih.gov/pubmed/16914326
http://www.ncbi.nlm.nih.gov/pubmed/16619285
http://www.ncbi.nlm.nih.gov/pubmed/17548517
http://www.ncbi.nlm.nih.gov/pubmed/18209064
http://www.ncbi.nlm.nih.gov/pubmed/18198346
http://www.ncbi.nlm.nih.gov/pubmed/14707119
http://www.ncbi.nlm.nih.gov/pubmed/16141072
http://www.ncbi.nlm.nih.gov/pubmed/15878887
http://www.ncbi.nlm.nih.gov/pubmed/16116168
http://www.ncbi.nlm.nih.gov/pubmed/16323246
http://www.ncbi.nlm.nih.gov/pubmed/17463084
http://www.ncbi.nlm.nih.gov/pubmed/16086018
http://www.ncbi.nlm.nih.gov/pubmed/17952078
http://www.ncbi.nlm.nih.gov/pubmed/18394936
http://www.ncbi.nlm.nih.gov/pubmed/16623599

 


The KO Repository lines exist as cryopreserved materials. Cohorts can typically be produced and delivered to the customer within 14-16 weeks of order receipt. For most lines, the mouse ES cells used in generating the model are of the 129S5 strain. Lines are stored primarily as cryopreserved sperm on a mixed 129S5 x C57BL/6J-Tyrc-Brd background. Lines are recovered using cryopreserved sperm and C57BL/6NTac oocyte donors. Some lines are stored as cryopreserved embryos and when revitalized will result in a 129/S5 x C57BL/6J-Tyrc-Brd background.

For standard orders clients will receive:

  • A minimum of four (4) Mutant Mice, heterozygous for the Selected Mutation, including at least one (1) breeding pair on a mixed 129S5;B6 background.
  • Validated genotyping protocols
  • Animal health data

Commercial Pricing:

Number of Lines PurchasedPrice per Line ($)Price per Line for Comprehensive Phenotype Data ($)
Single Line 45,000 25,000
2 Lines 40,500 25,000
3 Lines 39,375 25,000
4+ Lines 38,250 25,000

Nonprofit Pricing:

Price per Line ($)Price per Line for Comprehensive Phenotype Data ($)
30,000 15,000
Basic Phenotype Package: $5,000
Multi-line discounts will be applied to lines ordered on a single purchase order (PO).

Commercial Pricing:

Number of Lines PurchasedPrice per Line (€)Price per Line for Comprehensive Phenotype Data (€)
Single Line 42,750 23,750
2 Lines 38,475 23,750
3 Lines 37,406 23,750
4+ Lines 36,338 23,750

Nonprofit Pricing:

Price per Line (€)Price per Line for Comprehensive Phenotype Data (€)
28,500 14,250
Basic Phenotype Package: €4,750
Multi-line discounts will be applied to lines ordered on a single purchase order (PO).