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Emerging Models

The Taconic Emerging Models Program offers access to developing models sponsored by various Principal Investigators. Animal models enrolled in the Taconic Emerging Models Program are listed below by sponsor, gene of interest, and Taconic model number. Some Emerging Models require execution of Material Transfer Agreements (MTAs) before orders may be placed. Please check the individual model pages for specific information. 

Deleter Strains

Model Name Nomenclature Model Number
Cd4-cre Transgenic B6.Cg-Tg(CD4-cre)1Cwi N9 4196
Lck-cre Transgenic B6.Cg-Tg(Lck-cre)1Cwi N9 4197
Cre-ERT2 C57BL/6NTac-Gt(ROSA)26Sortm9(Cre/ESR1)Arte 10471
Cre Deleter C57BL/6NTac-Gt(ROSA)26Sortm16(cre)Arte 12524
Flp Deleter C57BL/6-Tg(CAG-Flpe)2Arte 7089

Cancer Models

Model Name Nomenclature Model Number
Invasive Lobular Breast Cancer Model FVB.Cg-Cdh1tm1Jjon Trp53tm1Brn Tg(KRT14-cre)8Brn/A 11509
Brca1-Associated Breast Cancer Model FVB.Cg-Cdh1tm1Jjon Trp53tm1Brn Tg(KRT14-cre)8Brn/A 11510
Floxed Ink4a Mouse B6.129P2-Cdkn2atm2Brn/A 11511
Floxed p53 Mouse B6.129P2-Trp53tm2Brn/A 11512

Other Emerging Models

Model Name Nomenclature Model Number
B6 Albino A++ C57BL/6NTac-Atm1.1Arte Tyrtm1Arte 11227
B6 Albino C57BL/6NTac-Tyrtm1Arte 11971
HRN™ nude CrTac:NCr-Portm1Wolf Foxn1nu Tg(Alb-cre)21Mgn 9066
Rag2 Knockout/Transgenic DO11.10 T Cell Receptor B10.D2-Rag2tm1Fwa Tg(DO11.10)10Dlo/AiTac 4091
Rag2 Knockout/Transgenic Cyt5CC7 T Cell Receptor B10.A-Rag2tm1Fwa H2-T18a Tg (Tcra5CC7,Tcrb5CC7)lwep 4094
Tcrα Knockout/Transgenic LCMV P14 T Cell Receptor B6.Cg-Tcrαtm1Mom Tg(TcrLCMV)327Sdz 4138
CX3CR1 Knockout B6.129-Cx3cr1tm1Zm 4167
Fpr1 Knockout C57BL/6NTac-Fpr1tm1Gao N6 4169
Rag1 Knockout/Transgenic OT-I T Cell Receptor B6.129S7-Rag1tm1Mom Tg(TcraTcrb)1100Mjb N9+N1 4175
H2-Db B6.129P2-H2-Dbtm1 N12 4217
Rag1 Knockout/Transgenic OT-II T Cell Receptor B6.129S7-Rag1tm1Mom Tg(TcraTcrb)425Cbn 4234
Nos2 Knockout B6.129S2-Nos2tm1MrI N12 4236
IL15 Knockout C57BL/6NTac-IL15tm1Imx N5 4269
SAP/Sh2d1A Knockout B6.129-Sh2d1atm1Pls 8424

Learn more about the Taconic tADMET™ portfolio

Model Name Nomenclature Model Number
Pxr-Car Knockout Mouse C57BL/6-Nr1i2tm3Arte Nr1i3tm1.1Arte 8222
Humanized PXR-CAR Mouse C57BL/6-Nr1i2tm1(NR1I2)Arte Nr1i3tm1(NR1I3)Arte 8223
Cyp3a (7-gene) Knockout Mouse C57BL/6NTac-Del(5Cyp3a57-Cyp3a59)1Arte 8841
Humanized CYP3A4/3A7 Mouse C57BL/6-Del(5Cyp3a57-Cyp3a59)1Artetm1(CYP3A4-CYP3A7)Arte 8842
Humanized Gut CYP3A4 Mouse FVB.129P2-Cyp3a13tm1Ahs Del(5Cyp3a57-Cyp3a59)1Ahs Tg(Vil1-CYP3A4)1Ahs 9047
Humanized Liver CYP3A4 Mouse FVB.129P2-Cyp3a13tm1Ahs Del(5Cyp3a57-Cyp3a59)1Ahs Tg(APOE-CYP3A4)A1Ahs 9048
Humanized Liver & Gut CYP3A4 Mouse FVB.129P2-Cyp3a13tm1Ahs Del(5Cyp3a57-Cyp3a59)1Ahs Tg(Vil1-CYP3A4)1Ahs Tg(APOE-CYP3A4)A1Ahs 9049
Pxr Knockout Mouse C57BL/6-Nr1i2tm3Arte 9100
Humanized CAR Mouse C57BL/6-Nr1i3tm1(NR1I3)Arte 9101
Car Knockout Mouse C57BL/6-Nr1i3tm1.1Arte 9103
Humanized PXR Mouse C57BL/6-Nr1i2tm1(NR1I2)Arte 9104
Humanized AHR Mouse C57BL/6-Ahrtm1.1(AHR)Arte 9165
Ahr Knockout Mouse C57BL/6-Ahrtm1.2Arte 9166
Cyp2c Knockout Mouse B6-Cyp2ctm1104Arte 9177
Cyp2d Knockout Mouse C57BL/6-Del(15Cyp2d22-Cyp2d26)1Arte 9178
Humanized MRP2 Mouse C57BL/6-Abcc2tm1(ABCC2)Arte 9179
Pxr-Car-Ahr Knockout Mouse C57BL/6-Nr1i3tm1.1Arte Ahrtm1.2Arte Nr1i2tm3Arte 11583
Humanized CYP2D6 Mouse C57BL/6-Is(15CYP2D6;Del15Cyp2d22-Cyp2d26)3Arte 11584
Humanized PXR-CAR-CYP3A4/3A7 Mouse C57BL/6-Nr1i3tm1(NR1I3)Arte Is(5CYP3A4-CYP3A7;Del5Cyp3a57-Cyp3a59)2Arte Nr1i2tm1(NR1I2)Arte 11585
Humanized Liver CYP2C9 C57BL/6-Is(19Alb/CYP2C9;Del 19Cyp2c55-Cyp2c70)2Arte 11746
Humanized PXR-CAR-AHR Mouse C57BL/6-Nr1i3tm1(NR1I3)Arte Ahrtm1.1(AHR)Arte Nr1i2tm1(NR1I2)Arte 12657
Pxr-Car-Pparα Knockout Mouse C57BL/6-Nr1i3tm1.1Arte Pparatm3Arte Nr1i2tm3Arte 12658
Humanized PXR-CAR-CYP3A4/3A7-CYP2D6 Mouse C57BL/6-Nr1i3tm1(NR1I3)Arte Is(5CYP3A4-CYP3A7;Del5Cyp3a57-Cyp3a59)2Arte Cyp3a13tm1.1Arte Is(15CYP2D26;Del15Cyp2d22-Cyp2d26)3Arte Nr1i2tm1(NR1I2)Arte 12659
Humanized PXR-CAR PPARα Mouse C57BL/6-Nr1i3tm1(NR1I3)Arte Pparatm3.1(PPARa)Arte Nr1i2tm1(NR1I2)Arte 12660
Cyp1a1-Cyp1a2 Knockout Mouse C57BL/6-Cyp1a2/Cyp1a1tm1.2Arte 12661
Cyp3a (7-gene)-Cyp2c-Cyp2d Knockout Mouse C57BL/6-Del(5Cyp3a57-Cyp3a59)1Arte Del(15Cyp2d22-Cyp2d26)2Arte Del 19(Cyp2c55-Cyp2c70)1Arte 12662
Humanized CYP1A1-CYP1A2 Mouse C57BL/6-Cyp1a2/Cyp1a1tm1.1(CYP1A2/CYP1A1)Arte 12663
Model Name Nomenclature Model Number Field of Application Sponsoring Institution & Investigator
CIEA NOG mouse® NOD.Cg-Prkdcscid Il2rgtm1Sug/JicTac NOG Oncology, infectious Disease, immunology, humanization Central Institute of Experimental Animals and In-Vivo Science International
CIEA BRG mouse C.Cg-Rag2tm1Fwa Il2rgtm1Sug/JicTac 11503 Oncology, infectious disease, immunology, humanization Central Institute of Experimental Animals and In-Vivo Science International
hGM-CSF/hIL3-NOG NOD.Cg-B2mtm1Jae PrkdcscidIl2rgtm1Sug/JicTac 13395 Oncology, infectious disease, immunology, regenerative medicine, humanization Central Institute of Experimental Animals and In-Vivo Science International
TK-NOG NOD.Cg-Prkdcscid Il2rgtm1Sug Tg(Alb-TK)7-2/ShiJic 12907 Humanization of liver and/or immune system, safety assessment Central Institute of Experimental Animals and In-Vivo Science International
B2m-NOG NOD.Cg-B2mtm1Jae PrkdcscidIl2rgtm1Sug/JicTac 13439 Oncology, immunology, humanization Central Institute of Experimental Animals and In-Vivo Science International

Live LPTA® Models

  • β-Actin-luc (murine beta actin promoter) (FVB/N background) - Model #10498
  • NFκB-RE-luc (NFκB response elements) - Model #10499
  • β-Actin-luc (murine beta actin promoter) (B6;FVB (albino) background) - Model #10500
  • Gfap (glial fibrillary acidic protein) - Model #10501

Inflammation
Model Name Background Application(s) Availability
Gadd45b
(Growth Arrest & DNA Damage Inducible 45-Beta)
CD-1
Cancer - apoptosis; MAP kinase- and NF-κB-mediated signaling pathways; inflammation
Cryo
Epx* or Epo
(eosinophil peroxidase)
FVB/N
Eosinophila - parasitism or asthma; bone marrow transplantation
Cryo
Saa1
(serum amyloid A-1)
BALB/c
Arthritis, amyloidosis, sepsis
Cryo
IL-2
(interleukin-2)
CD-1
Inflammation, cancer
Cryo
Cox2 or Ptgs2
(cyclooxygenase-2)
BALB/c
Inflammation, pain
Cryo
(tumor necrosis factor-α)
BALB/c
Inflammation - arthritis or inflammatory bowel disease; cancer - apoptosis; sepsis
Cryo
NFκB-RE-luc
(NFκB response elements)
BALB/c
Inflammation - arthritis or inflammatory bowel disease; cancer - apoptosis
Live as model #10499
IκBα
([inhibitor of NFκB]α)
BALB/c
Inflammation - arthritis or inflammatory bowel disease; cancer - apoptosis; sepsis
Cryo

Oncology / Angiogenesis
(vascular endothelial growth factor receptor-2)
FVB/N
Inflammation; angiogenesis processes incl. embryonic or post-natal development, wound healing
Cryo
Vegfr2-KI (knock in)
(vascular endothelial growth factor receptor-2)
C57BL/6 Albino
Cancer, inflammation; angiogenesis processes incl. embryonic or post-natal development, wound healing
Cryo
Vegfr2-KI (knock in)
(vascular endothelial growth factor receptor-2)
STOCK nude (nu/nu)
Cancer, inflammation; angiogenesis processes incl. embryonic or post-natal development, wound healing
Cryo
Vegf
(vascular endothelial growth factor)
FVB/N
General angiogenesis reporter
Cryo
(Elastase 1)
FVB/N
Spontaneous and bioluminescent pancreatic tumor model
Cryo

Drug Metabolism / Toxicology
CYP3A4
(cytochrome p450 isoform 3A-human promoter)
FVB/N
Drug metabolism; CYP3A4 gene regulation studies; CYP3A4-mediated drug-drug interactions
Cryo
Cyp3a11*
(cytochrome p450 isoform 3a-mouse promoter)
FVB/N
Drug metabolism; Cyp3a11-mediated drug-drug interactions
Cryo
CYP3A4 RAT*
(cytochrome p450, isoform 3A-human promoter)
SD Rat
Drug metabolism; CYP3A4 gene regulation studies; CYP3A4-mediated drug-drug interactions
Cryo
Cyp1a1
(cytochrome p450, isoform 1a2-mouse promoter)
CD-1
Drug metabolism; Cyp1a1 mediated drug-drug interactions
Cryo
Cyp1a2
(cytochrome p450, isoform 1a2-mouse promoter)
CD-1
Cyp1a2-mediated drug-drug interactions; toxicity
Cryo
Cyp2c9
(cytochrome p450, isoform 1a2-mouse promoter)
CD-1
Drug metabolism; Cyp1c9 mediated drug-drug interactions
Cryo
Cyp19 or Aro
(aromatase)
CD-1
Estrogen synthesis; regulation of estrogen production
Cryo
γGcs-h or Gclc
(γ-glutamylcysteine synthetase)
CD-1
Heavy metal and chemical toxicity - CdCl2, chloroform, or MeHg; chemoprotection
Cryo
Sod1
(superoxide dismutase)
CD-1
Toxicity including heavy metal and chemical - CdCl2
Cryo
Mdr1 or Abcb1b
(multiple drug resistance-1)
Mdr1
Drug transport
Cryo
Gadd45α
(growth arrest & DNA damage inducible 45-alpha)
CD-1
Toxicity - heavy metal and chemical
Cryo
Gadd153
(growth arrest & DNA damage inducible 153)
CD-1
Toxicity - heavy metal and chemical
Cryo

Endrocrine Disruptor
Kap
(kidney androgen regulated promoter)
FVB/N
Kap gene regulation; androgen regulation; endocrine disruption
Cryo
pS2/TFF1
(trefoil peptide-1)
FVB/N
Inflammatory bowel disease; colitis; gastric ulcer
Cryo
Mup1
(major urinary protein-1, or alpha-2u globulin)
FVB/N
Mup gene regulation; androgen; endocrine disruption
Cryo
Esr1
(estrogen receptor-alpha)
CD-1
Esr1 gene regulation studies
Cryo

Metabolic Disease
(rat insulin gene promoter)
FVB/N
Insulin production applications; pancreatic islet transplantation
Cryo
Retn
(resistin)
C57BL/6
Obesity - fasting, high-fat feeding, insulin resistance; obesity - adipose tissue transplantation
Cryo
mIns2
(mouse insulin provider)
C57BL/6
Insulin production changes studies resulting from fasting, high-fat feeding, streptozotocin, or pancreatic islet transplantation
Cryo

Other Disease Areas and Adoptive Transfer Models
Bmp4
(bone morphogenetic protein-4)
FVB/N
Wound healing, estrogen modulation of gene expression
Cryo
Gfap
(glial fibrillary acidic protein)
FVB/N
Astrocyte regeneration (primarily CNS), including physical trauma, chemical insult, or meningitis
Live as model #10501
β-Actin-luc
(murine beta actin promoter)
FVB/N
Model may be used as donor animals for studying the tranplantation of various tissue types.
Live as model #10498
β-Actin-luc
(murine beta actin promoter)
B6;FVB (albino)
Model may be used as donor animals for studying the tranplantation of various tissue types.
Live as model #10500
Lines listed as live are available for immediate purchase in typical study quantities. Lines listed as cryo are available for immediate cryorecovery and contract production. Please contact Taconic for additional information about cryopreserved lines.

All of the transgenic models are in MICE except for the CYP3A4 which has been developed in both mouse and rat. The gene abbreviations presented are those most commonly used in NCBI locus link, GENBANK, the Mouse Genome Informatics database, and in the literature. In some cases two alternative abbreviations for the same gene are given. Most of the models consist of the mouse promoter driving the luciferase reporter. These are indicated with gene abbreviation in lower case other than the first letter that is capitalized. For a few of the transgenic models, the human promoter was used. A gene abbreviation in all upper case indicates the model uses a human promoter.

LPTA® animal models are made available from Taconic under a license from Caliper Life Sciences and Promega Corporation. Other third party rights may apply.

Sponsored by The Michael J. Fox Foundation and available from Taconic


Model # Model Name Nomenclature
10678 Human Alpha Synuclein A53T Rat NTac:SD-Tg(SNCA*A53T)268Cjli
10679 Human Alpha Synuclein E46K Rat NTac:SD-Tg(SNCA*E46K)70Cjli
10680 Human Alpha Synuclein Rat NTac:SD-Tg(SNCA)446Cjli
10681 Human LRRK2 G2019S Rat NTac:SD-Tg(LRRK2*G2019S)571Cjli
12141 hTH-GFP Rat NTac:SD-Tg(TH-EGFP)24Xen
10677** Human LRRK2 R1441G Rat NTac:SD-Tg(LRRK2*R1441G)358Cjli

Features:


Mutations in the LRRK2 and SNCA (alpha synuclein) genes are associated with familial Parkinson's disease. Each of these four rat models feature a transgene expressing one of these two human genes, either as wild type or with relevant mutations. Mutations in alpha-synuclein and LRRK2 cause familial PD (Park 1 and Park 8) in a dominant inheritance manner. For alpha synuclein, A53T, A30P, E46K mutations and gene duplication/triplication can lead to PD. For LRRK2, G2019S is the most prevalent mutation found in familial and sporadic PD. R1441G is another prominent mutation, which was identified during the process of genetic mapping and disease gene cloning. The rat as an experimental organism can offer some unique strengths compared to mice. For example, rats can perform more sophisticated behavioral tasks, and are better suited for electrophysiological multichannel recordings. The nigrostriatal circuit of the rat is also more sensitive to insults than that of mice. In these transgenic rats, transgenes are expressed to make full length proteins (please see Expression Analysis provided under Related Publications). These animals are being analyzed for their pathological, neurochemical, and behavioral phenotypes. Cannon et al., have shown Parkinsonian phenotype in the Human Alpha Synuclein E46K Rat (Model 10679).

Dopamine neurons are susceptible to damage/loss in Parkinson's disease and the hTH-GFP rat provides a research tool for studying this process. The hTH-GFP rat carries an EGFP transgene driven by the human Tyrosine Hydroxylase promoter. High-level specific EGFP expression is seen in dopaminergic neurons. The hTH-GFP rat is useful for in vivo and in vitro studies of dopamine neuron function and degeneration in Parkinson's disease.

** Note: Distribution of the Human LRRK2 R1441G Rat (Model 10677) has been discontinued. Expression analysis shows that the transgene expresses poorly.
  • A panel of luciferase reporter mice to assay GPCR ligand binding and pathway activation in various tissues.
  • CNS (brain and spinal cord) specific expression of CRE-Luc reporter.
  • Same reporter system supports in vitro (primary neuronal cultures), in vivo (whole animal), or ex vivo (brain slice) assays.
  • Platform can provide rapid in vivo PK/PD profiling of compounds with quantitative data to compare pharmacological action.
  • Assay can be used for two main GPCR classes, Gs and Gi
Learn more about the Cre-Luc GPCR Reporter Mouse Platform.
Model Name Nomenclature Model Number Field of Application Sponsoring Institution & Investigator
TNF-alpha; B6.129 - TNFtm1Ljo N7 1921   Ludwig Institute Ritter
Model Name Nomenclature Model Number Field of Application Sponsoring Institution & Investigator
SOD1 NTac:SD-Tg(SOD1G93A)L26H 2148 ALS research The ALS Association
Cancer Research Technology (CRT) is a specialist commercialization and development company, which aims to develop new discoveries in cancer research for the benefit of cancer patients.  CRT is a wholly owned subsidiary of Cancer Research UK, the world’s largest cancer charity, and has exclusive rights to intellectual property from Cancer Research UK funded research – more than £300M annually.  The CRT Repository represents valuable research tools arising from such research, which CRT now makes widely available to the worldwide research community through distribution by Taconic.

The CRT models are stored at Taconic as cryopreserved materials.  To access a line, researchers must sign a limited breeding agreement, and then the line is recovered via derivation.  There are fees for both the agreement and derivation.  Taconic can maintain live colonies of recovered lines on a contract basis, or researchers may breed them at their own facility.
Model Name Nomenclature Model Number Field of Application Sponsoring Institution & Investigator
Cdh5(PAC)-CreERT2 Mouse B6.CBA-Tg(Cdh5-cre/ERT2)1Rha 13073 Oncology Cancer Research Technology (CRT)
Floxed Dll1 Mouse B6;129-Dll1tm1Mjo 13074 Oncology Cancer Research Technology (CRT)
Pdgfrb-Cre Mouse B6;129-Tg(Pdgfrb-cre)9Rha 13075 Oncology Cancer Research Technology (CRT)
Trex1 Knockout Mouse B6;129P2-Trex1tm1Tld 13076 Oncology Cancer Research Technology (CRT)
Model Name Nomenclature Model Number Disposition Sponsoring Institution & Investigator
Rag2tm1 TgN(N15) B6;129S6 421 No longer available Dana Farber Reinherz
Rag2tm1 TgN(AND) STOCK 422 No longer available Dana Farber Reinherz
Igg3tm1 BALB/c 632 No longer available Case Western Schreiber
Pik3r1tm1 C57BL/6 N7 725 No longer available. N12 model available from RIKEN Keio University Koyasu
Pik3r1tm1 BALB/c N7 738 No longer available. N12 model available from RIKEN Keio University Koyasu
Chromosome of interest: 4 NOD.B10-Idd9.1 Idd9.2 Idd9.3 N12 905 Available at Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
Chromosome of Interest 4 Idd9r11 907 No longer available, replaced with Model 1566 University of Cambridge Todd
Chromosome of interest 1   974 Available from the Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge Todd
Pik3r1tm1 C57BL/6 1077-M No longer available. Now available from RIKEN Keio University Koyasu
Pik3r1tm1 BALB/C 1078-M No longer available. Now available from RIKEN Keio University Koyasu
Chromosome of interest 1 1092 Available from the Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
Idd54467 NOD.B6 1095 Now available as Model 2574 University of Cambridge Todd
Idd10 Idd18r2 NOD.B6 1101 No longer available; replaced with model 7754 University of Cambridge
Chromosome of Interest 4 Idd9r28 1104 Now available as Model 905 University of Cambridge Todd
Chromosome of Interest 4 Idd9r11> 1105 Now available as Model 1566 University of Cambridge Todd
NOD.B10-Idd9.3 Line 1106 NOD.B10-Idd9.3 N14 1106 Available from the Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
Chromosome of interest 17 H2g7 1107 Available from the Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
17 b 1108 Available from the Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
H2h4 NOD.B10 1109 Available from the Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge Todd
NOD.B6-Idd3 Idd17 Idd10 Idd18 B10-Idd9 Line 1112 NOD.B6-Idd3 Idd17 Idd10 Idd18 B10-Idd9 N6 1112 This line has been discontinued. If you have long-term needs for this model, please setup a breeding colony, either at Taconic or at your own facility. Contact us immediately to purchase the necessary breeding animals. To be available from the Type 1 Diabetes Resource at the Jackson Laboratory. Univeristy of Cambridge
Idd3 and Idd5 NOD.B6 1111
1591
No longer available University of Cambridge Todd
TgN(APPSWE) 2576 B6;SJL 1349 Available as Commercial Model 1349 Mayo Clinic Stoddard
TgN(HO-1-luc) FVB 1514-M No longer available Xenogen Campbell
Abbtm1 Tlr4 Sic11a1 STOCK 1517 No longer available Kansas State University Chapes
Chromosome of interest: 3 NOD.B6-Idd3 Idd10 Idd18 N12 1538 Available at Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
Chromosome of interest: 4 NOD.B10-Idd11 Idd9.1 N12 1565 Available at Type 1 Diabetes Resource at the Jackson Laboratory University of Cambridge
1 & 3 R450/467 1573 No longer available University of Cambridge
TgN(iNOS-Luc)X-xen FVB 1582 No longer available Caliper Life Sciences
Rag2tm1 TgN(OT-II.2) C57BL/6 1896 Available now as Taconic Transgenic Model Rag2/OT-II Keio University Koyasu
Rag2tm1 TgN(OT-I.1) C57BL/6 2334 Available now as Taconic Transgenic Model Rag2/OT-I. Keio University Koyasu
Chromosome of interest: 1 NOD.B10-Idd5.1 N16 2574 No longer available University of Cambridge
BALB/c-plgRtm1 BALB/c 3767 No Longer Available Albany Medical College
Metzger
C57BL/6-plgRtm1 C57BL/6 3768 No Longer Available Albany Medical College
Metzger
Rag2 Knockout/Transgenic LCMV-P14 T Cell Receptor B10;B6-Rag2tm1Fwa Tg(TcrLCMV)327Sdz 4113 No longer available NIAID Schwartz
TgN(Cd-4Cre) STOCK N2 4214 Now available as model 4196. NIAID Schwartz
p47 phox Knockout B6.129S2-Ncf1tm1Shl N14 4227 No longer available NIAID Schwartz
B10.Q/Ai B10.D1-H2q/SgAi 4059 No longer available NIAID Schwartz
CCR1 Knockout B6.129S4-Ccr1tm1Gao N10+N5 4087 No longer available NIAID Schwartz
II4ra Knockout BALB/cJ-Il4ratm1Sz 4177 No longer available NIAID Schwartz
Flt3l Knockout C57BL/6-flt3Ltm1Imx 4207 No longer available NIAID Schwartz
H2-Kb H2-Db Double Knockout B6.129P2-H2-Kbtm1 H2-Dbtm1 N12 4215 No longer available NIAID Schwartz
H2-Kb Knockout B6.129P2-H2-Kbtm1 N12 4216 No longer available NIAID Schwartz
Rag2 Knockout/Transgenic DO11.10 T Cell Receptor C.Cg-Rag2tm1Fwa Tg(DO11.10)10Dlo 4219 No longer available NIAID Schwartz
LTH-1 Transgenic B6.SJL-Tg(Lck-tTA)1Dim N10 4245 No longer available NIAID Schwartz
Transgenic D011.10 T Cell Receptor/Transgenic CAR BALB/cJ-Tg(DO11.10)10Dlo Tg(CARΔ-1)1Jdgr 4285 No longer available NIAID Schwartz
Rag2 Knockout/Transgenic LCMV-P14 T Cell Receptor B10.Cg-Rag2tm1Fwa Tg(TcrLCMV)327Sdz 4356 No longer available NIAID Schwartz
Ptgs-1tm1 B6;129P2 5001 Now available as Commercial Model 2180 NIEHS Langenbach
Ptgs-2tm1 B6;129P2 5002 Now available as commercial model 2181