With increasing use of and dependency on GEMs, many researchers are considering a GEMs risk management program. Such programs can safeguard a researcher's unique and valuable model from health, genetic and natural disasters.

A model can be lost if the mutation of interest disappears, if the model faces genetic contamination or if the line becomes infected by a pathogen incompatible with standards of the animal facility, leading to an immediate termination of the colony. Also, natural disasters can lead to total loss of unique GEMs. Often, however, losing a model doesn't happen in extreme situations but rather during normal operating conditions. Basic equipment failure, such as flooding of cages or technician error through incorrect breeding, can lead to a total loss of a GEM.

The nightmare scenario of GEM-based research is a total loss of the underlying model. Consequences, including a delay in research time, can possibly render any accomplished research unusable, with implications such as an extended study timeline.

Off-site cryostorage

Storage of cryopreserved sperm and embryos at an off-site location, offers a realistic solution for risk mitigation. Taconic provides dual site storage for any cryopreserved sperm or embryos held at Taconic. Not only are your stocks held in 2 different freezers, those freezers are in physically separated buildings in different geographic locations. Additionally, the freezers are alarmed with 24 hr monitoring.

Taconic accepts materials regardless of where the cryopreservation was completed. You can consider Taconic as part of your institution's dual site storage program by depositing up to half of cryopreserved material with Taconic.